Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Lennart Florvall"'
Publikováno v:
Scopus-Elsevier
The antidopaminergic potencies of some new substituted benzamides related to remoxipride have been studied in the rat using in vitro (3H-spiperone binding) and in vivo techniques (antagonism of apomorphine induced stereotypies). The lipophilicities o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4a05b9d9b556e5d6e0c703c49d571f6
https://doi.org/10.1111/j.1600-0773.1984.tb02039.x
https://doi.org/10.1111/j.1600-0773.1984.tb02039.x
Autor:
Viveka Hillegaart, Agneta Wijkström, Sven Ahlenius, Evalena Ericson, Lennart Florvall, Patricia Jimenez
Publikováno v:
European Journal of Pharmacology. 394:247-253
Behavioral and biochemical techniques were used to compare the in vivo intrinsic efficacy of two new 2-(4-aminophenyl)-N, N-dipropylethylamine dopamine D(2) receptor agonists, 2-(4-amino-3-trifluoromethylphenyl)-N-N-dipropyl-ethylamine (NBF-203) and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af3fb0cce727dac1c4493650ac70aa4a
https://doi.org/10.1016/s0014-2999(00)00158-8
https://doi.org/10.1016/s0014-2999(00)00158-8
Publikováno v:
European Journal of Medicinal Chemistry. 34:137-151
Six amino acid derivatives of 1-(4-aminophenyl)-2-aminopropanes and their parent amines were synthezised and tested for their potency and selectivity in inhibiting monoamine oxidase (MAO) in vitro and in vivo. The amino acid derivatives were 300–10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b0f82afea54b9b38cbe157aef33eaeaf
https://doi.org/10.1016/s0223-5234(99)80047-6
https://doi.org/10.1016/s0223-5234(99)80047-6
Publikováno v:
European Journal of Medicinal Chemistry. 31:133-142
Summary A series of 2-(4-aminophenyl)- N,N -dipropylethylamine derivatives were synthesized and tested for in vivo intrinsic activity at brain dopamine receptors in the rat. Differences in the sensitivity of dopamine receptors pre- and post-synaptica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::61e45bb3e6152ba81936ba5aefc1d573
https://doi.org/10.1016/0223-5234(96)80446-6
https://doi.org/10.1016/0223-5234(96)80446-6
Publikováno v:
European Journal of Medicinal Chemistry. 29:191-195
The PLS method is used to derive improved quantitative structure-activity relationships for some monoamine oxidase (MAO) inhibitors of the phenyl alkylamine type. The established models for in vivo responses in NA, DA and 5-HT neurons indicate that s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e4453b2777230b75c43dcb4617a90b9a
https://doi.org/10.1016/0223-5234(94)90037-x
https://doi.org/10.1016/0223-5234(94)90037-x
Publikováno v:
ChemInform. 30
Six amino acid derivatives of 1-(4-aminophenyl)-2-aminopropanes and their parent amines were synthezised and tested for their potency and selectivity in inhibiting monoamine oxidase (MAO) in vitro and in vivo. The amino acid derivatives were 300–10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f921e937a6f124cb40f09d7ba35b44b
https://doi.org/10.1002/chin.199929187
https://doi.org/10.1002/chin.199929187
Autor:
Lennart Florvall, Toshiaki Nishida, Sven-Olov Lawesson, Maj-Liz Persson, Jan-Eric Berg, Curt R. Enzell
Publikováno v:
Acta Chemica Scandinavica. :141-146
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7da3f6719e68822cb2bc3ff23ee4920a
https://doi.org/10.3891/acta.chem.scand.36b-0141
https://doi.org/10.3891/acta.chem.scand.36b-0141
Publikováno v:
Scopus-Elsevier
A series of derivatives of 4-aminophenethylamine was synthesized and their effect on monoamine oxidase (MAO) activity in the brain was evaluated. Several of the new compounds were potent and selective inhibitors of the A form of MAO but were poor inh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86d84aeb27ad80c2686ca7299cffe270
https://doi.org/10.1021/jm00199a010
https://doi.org/10.1021/jm00199a010
Autor:
Olle Magnusson, Lars-Olof Lindbom, Christer Köhler, Lennart Florvall, K. Ängeby, H. Hall, Sven-Ove Ögren
Publikováno v:
European Journal of Pharmacology. 102:459-474
The novel substituted benzamide, remoxipride, preferentially blocked apomorphine-induced hyperactivity with weak effects on stereotypies. The potency of remoxipride was about 50 times higher than that of sulpiride. Remoxipride caused a weak, atypical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4a5061ab86ea45d668dc43c56ec7ff9
https://doi.org/10.1016/0014-2999(84)90567-3
https://doi.org/10.1016/0014-2999(84)90567-3
Autor:
de Paulis T, Sven Ove Ögren, K. Angeby-Moller, Lennart Florvall, Lars Johansson, Haakan Olof Hall, Y. Kumar, Rämsby S
Publikováno v:
Scopus-Elsevier
A series of substituted 6-methoxysalicylamides were synthesized from their corresponding 2,6-dimethoxybenzamides by demethylation of one methoxy group with boron tribromide. Substituted 6-methoxysalicylamides having a lipophilic aromatic substituent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e29cb546b09efa705b251dda396d4296
https://pubmed.ncbi.nlm.nih.gov/4040977
https://pubmed.ncbi.nlm.nih.gov/4040977