Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Lenke Tari"'
Autor:
Yasaman Ataei, Larry Park, D. James Surmeier, B. Joseph Vu, Seung Kwak, Richard T. Surosky, Anand Narayanan, David A. Shivak, Josee Laganiere, Christer Halldin, Andrea Varrone, Matthew C. Mendel, Karsten Tillack, Lei Zhang, Bryan Zeitler, Dmitry Guschin, Lexi Kopan, Sarah J. Hinkley, Kimberly Marlen, Jocelynn R. Pearl, Qi Yu, Taneli Heikkinen, Annette Gärtner, Yalda Sedaghat, Christina Thiede, Miklós Tóth, Jennifer M. Cherone, David Paschon, Jyothisri Kondapalli, Andrea E. Kudwa, Ladislav Mrzljak, Rainier Amora, Kimmo Lehtimäki, Edward J. Rebar, Lenke Tari, Ignacio Munoz-Sanjuan, Jeffrey C. Miller, Sylvie Ramboz, Marie Svedberg, Steven Froelich, Irina Ankoudinova, Philip D. Gregory, Stephen Lam, Michelle Day, Jonathan Bard, Hoang Oanh B. Nguyen, Fyodor D. Urnov, Davis Li, Jenny Haggkvist, H. Steve Zhang, Guijuan Qiao
Publikováno v:
Nature Medicine. 25:1131-1142
Huntington’s disease (HD) is a dominantly inherited neurodegenerative disorder caused by a CAG trinucleotide expansion in the huntingtin gene (HTT), which codes for the pathologic mutant HTT (mHTT) protein. Since normal HTT is thought to be importa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d19307c1ae395108f0cf1b74fb590fb6
https://doi.org/10.1038/s41591-019-0478-3
https://doi.org/10.1038/s41591-019-0478-3
Autor:
Raisa, Krasikova, Mikhail, Kondrashov, Camilla, Avagliano, Mikhail, Petukhov, Ana, Vazquez-Romero, Evgeny, Revunov, Peter, Johnström, Lenke, Tari, Miklós, Tóth, Jenny, Häggkvist, Sophie, Erhardt, Simon, Cervenka, Magnus, Schou
Publikováno v:
ACS chemical neuroscience. 11(12)
The positron emission tomography (PET) radioligand α-[
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6559298df015c405fcd3616c575b723a
https://pubmed.ncbi.nlm.nih.gov/32343551
https://pubmed.ncbi.nlm.nih.gov/32343551
Autor:
Mohammad Mahdi, Moein, Miklós, Tóth, Lenke, Tari, Andrea, Varrone, Mohamed, Abdel-Rehim, Christer, Halldin
Publikováno v:
Talanta. 208
The blood plasma radiometabolite analysis (RMA) is crucial procedure for quantitative analysis of positron emission tomography (PET) radioligands with no original reference region in the brain. Blood sampling and separating plasma for RMA has been a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b26e3ac9dfbaac4a1ebe3a706cf2a2f3
https://pubmed.ncbi.nlm.nih.gov/31816716
https://pubmed.ncbi.nlm.nih.gov/31816716
Autor:
Andrea Varrone, Lenke Tari, Mohammad Mahdi Moein, Miklós Tóth, Christer Halldin, Mohamed Abdel-Rehim
Publikováno v:
Talanta. 208:120449
The blood plasma radiometabolite analysis (RMA) is crucial procedure for quantitative analysis of positron emission tomography (PET) radioligands with no original reference region in the brain. Blood sampling and separating plasma for RMA has been a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a18ea88b415d106dd35190a319985f8
https://doi.org/10.1016/j.talanta.2019.120449
https://doi.org/10.1016/j.talanta.2019.120449
Autor:
Akihiro Takano, Lars Farde, Peter Johnström, Dean G. Brown, Maria Nilsson, Anders Juréus, Sjoerd J. Finnema, Jonas Malmquist, Nahid Amini, Lenke Tari, Jenny Häggkvist, Steven Wesolowski, Scott Throner, Magnus Schou, Ryuji Nakao, Katarina Varnäs, Charlotte Ahlgren
Publikováno v:
ACS Chemical Neuroscience. 7:177-184
The histamine type 3 receptor (H3) is a G protein-coupled receptor implicated in several disorders of the central nervous system. Herein, we describe the radiolabeling and preclinical evaluation of a candidate radioligand for the H3 receptor, 4-(1S,2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::397297fd2c137bae554b23e7b6a2ef10
https://doi.org/10.1021/acschemneuro.5b00268
https://doi.org/10.1021/acschemneuro.5b00268
Autor:
Bryan, Zeitler, Steven, Froelich, Kimberly, Marlen, David A, Shivak, Qi, Yu, Davis, Li, Jocelynn R, Pearl, Jeffrey C, Miller, Lei, Zhang, David E, Paschon, Sarah J, Hinkley, Irina, Ankoudinova, Stephen, Lam, Dmitry, Guschin, Lexi, Kopan, Jennifer M, Cherone, Hoang-Oanh B, Nguyen, Guijuan, Qiao, Yasaman, Ataei, Matthew C, Mendel, Rainier, Amora, Richard, Surosky, Josee, Laganiere, B Joseph, Vu, Anand, Narayanan, Yalda, Sedaghat, Karsten, Tillack, Christina, Thiede, Annette, Gärtner, Seung, Kwak, Jonathan, Bard, Ladislav, Mrzljak, Larry, Park, Taneli, Heikkinen, Kimmo K, Lehtimäki, Marie M, Svedberg, Jenny, Häggkvist, Lenke, Tari, Miklós, Tóth, Andrea, Varrone, Christer, Halldin, Andrea E, Kudwa, Sylvie, Ramboz, Michelle, Day, Jyothisri, Kondapalli, D James, Surmeier, Fyodor D, Urnov, Philip D, Gregory, Edward J, Rebar, Ignacio, Muñoz-Sanjuán, H Steve, Zhang
Publikováno v:
Nature medicine. 25(7)
Huntington's disease (HD) is a dominantly inherited neurodegenerative disorder caused by a CAG trinucleotide expansion in the huntingtin gene (HTT), which codes for the pathologic mutant HTT (mHTT) protein. Since normal HTT is thought to be important
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4d3620bad8fe21aa64bd37ef53578561
https://pubmed.ncbi.nlm.nih.gov/31263285
https://pubmed.ncbi.nlm.nih.gov/31263285
Autor:
Lenke Tari, Hideyuki Igawa, Akihiro Takano, Miklós Tóth, Jenny Häggkvist, Christer Halldin, Shoki Okuda, Shizuo Kasai, Vladimir Stepanov, Syunsuke Yamamoto, Yasutaka Nagisa, Marie Svedberg
Publikováno v:
Current radiopharmaceuticals. 10(1)
Background and Objective: Melanin-concentrating hormone (MCH) is an attractive target for antiobesity agents and many drug discovery programs have been dedicated to identify smallmolecule antagonists of melanin-concentrating hormone receptor 1 (MCHR1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c4f34b407f0f521903640bb9f79d980
https://pubmed.ncbi.nlm.nih.gov/28034352
https://pubmed.ncbi.nlm.nih.gov/28034352
Autor:
Celia Dominguez, Ignacio Munoz-Sanjuan, Christer Halldin, Katarina Varnäs, Lenke Tari, Andrea Varrone, Jonathan Bard, Anton Forsberg, John Wityak, Ladislav Mrzljak, Jenny Häggkvist, Sangram Nag, Miklós Tóth, Marie Svedberg
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 58(4)
Since the discovery of the HTT gene in 1993, numerous animal models have been developed to study the progression of Huntington disease (HD) and to evaluate potential new therapeutics. In the present study, we used small-animal PET to characterize the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a74a01afba2ae9c150b9963211ee3fa0
https://pubmed.ncbi.nlm.nih.gov/27856625
https://pubmed.ncbi.nlm.nih.gov/27856625