Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Lenka Zahradová"'
Autor:
Ludek Pour, Sabina Sevcikova, Henrieta Greslikova, Renata Kupska, Petra Majkova, Lenka Zahradova, Viera Sandecka, Zdenek Adam, Marta Krejci, Petr Kuglik, Roman Hajek
Publikováno v:
Haematologica, Vol 99, Iss 2 (2014)
Even in the era of new drugs, multiple myeloma patients with extramedullary relapse have a poor prognosis. Our goal was to analyze the frequency and outcome of extramedullary relapse occurring in relapsed multiple myeloma patients. In total, we analy
Externí odkaz:
https://doaj.org/article/0766d57b3426413996d8c3f579902bc9
Autor:
Karthick Raja Muthu Raja, Lucie Rihova, Lenka Zahradova, Maria Klincova, Miroslav Penka, Roman Hajek
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e47077 (2012)
BACKGROUND: Regulatory T (Treg) cells play an important role in the maintenance of immune system homeostasis. Multiple myeloma (MM) is a plasma cell disorder frequently associated with impaired immune cell numbers and functions. METHODS: We analyzed
Externí odkaz:
https://doaj.org/article/8cf8adbe7bbc4b2991ac3f9babec0bc9
Autor:
Sabina Ševčíková, Zdeněk Adam, I. Vonke, Aneta Mikulasova, Jiří Jarkovský, Marta Krejčí, Vladimir Maisnar, Jarmila Obernauerova, Ivan Spicka, Lenka Zahradová, Petr Kessler, Luděk Pour, Viera Sandecká, Lucie Říhová, Vlastimil Scudla, Zdeněk Král, Dagmar Adamova, L. Walterová, Lucie Brožová, Jiří Minařík, Roman Hájek, Kamila Valentova, Jan Straub, Evžen Gregora, David Starostka, Jakub Radocha, Marek Wrobel
Publikováno v:
European journal of haematology. 99(1)
IntroductionMonoclonal gammopathy of undetermined significance (MGUS) is a premalignant condition with a risk of malignant conversion. Patients and methodsWith the aim to estimate the cumulative risk MGUS progression to hematologic malignancies, we a
Similar efficacy of thalidomide- and bortezomib-based regimens for first relapse of multiple myeloma
Autor:
Lenka Zahradová, Jan Straub, Zdenek Adam, Jiri Minarik, Tomas Buchler, Krivanová A, Marta Krejčí, Roman Hájek, Ludek Pour, Evzen Gregora, Vlastimil Scudla, Jiri Mayer
Publikováno v:
Annals of Hematology. 90:1441-1447
Many regimens containing novel drugs have been developed for multiple myeloma (MM). It is not yet clear whether some of the novel agents are better than others. In a retrospective study, we have analyzed the outcomes of patients with first relapse of
Autor:
Petr Kuglík, Evzen Gregora, Ivan Spicka, Zdenek Adam, Henrieta Grešliková, Jana Tajtlova, Pavel Nemec, Zuzana Zemanova, Dana Králová, Hana Filková, Ludek Pour, Renata Kupská, Viera Sandecká, Kyra Michalova, Lenka Zahradová, Roman Hájek, Marta Krejčí, Jan Smetana, Tomas Buchler
Publikováno v:
Biology of Blood and Marrow Transplantation. 16(4):548-554
The prognostic significance of 1q21 gain, del(13)(q14), del(17)(p13), t(4;14)(p16.3;q32), and t(11;14)(q13;q32) detected by interphase fluorescein in situ hybridization (FISH) was studied in a cohort of 91 patients with newly diagnosed multiple myelo
Autor:
Olga Stehlíková, Renata Koukalová, Z Rehák, Lenka Zahradová, Marta Krejčí, Roman Hájek, Luděk Pour, Jiří Mayer, Jana Chovancová, Martin Klabusay, Zdeněk Adam, Petr Szturz
Publikováno v:
Leukemia & Lymphoma. 53:2089-2091
A male born in 1961, aged 46, was referred to our department for evaluation of splenomegaly and generalized lymphadenopathy aff ecting the cervical, axillary, mediastinal, retroperitoneal and inguinal regions. Laboratory data revealed an increased er
Autor:
Martina Almáši, Pavel Nemec, Jan Smetana, Zdenek Adam, Romana Zaoralová, Jan Frohlich, Lenka Zahradová, Henrieta Grešliková, Petr Kuglík, Ludek Pour, Aneta Mikulasova, Vladimíra Vallová, Viera Sandecká, Renata Kupská, Roman Hájek
Publikováno v:
BioMed Research International, Vol 2014 (2014)
BioMed Research International
BioMed Research International
Characteristic recurrent copy number aberrations (CNAs) play a key role in multiple myeloma (MM) pathogenesis and have important prognostic significance for MM patients. Array-based comparative genomic hybridization (aCGH) provides a powerful tool fo
Autor:
Jiri Jarkovsky, Fedor Kryukov, Katerina Gracova, Lenka Besse, Roman Hájek, Tomas Jelinek, Lenka Zahradová, Hana Šváchová, Lucie Rihova
Publikováno v:
Blood. 128:5608-5608
Background:Neural stem cell marker nestin is a suitable diagnostic and prognostic indicator of malignancy and potential cancer stem cells marker in solid tumors. Currently, nestin has been demonstrated as an epithelial-to-mesenchymal transition relat
Autor:
Lucie Burešová, Krivanová A, Tomas Buchler, Zdenek Adam, Lenka Zahradová, Jiri Vorlicek, Roman Hájek, Ludek Pour, Viera Sandecká, Marta Krejčí
Publikováno v:
Clinical Lymphoma and Myeloma. 9:151-153
Varicella-zoster virus (VZV) reactivation is a common complication in patients with multiple myeloma (MM) treated with bortezomib, with an incidence rate of 10%-60%. The aim of our study was to analyze the effect of acyclovir prophylaxis in this pati
Autor:
Sabina Ševčíková, Lenka Zahradová, Ludek Pour, Petra Májková, Renata Kupská, Zdenek Adam, Marta Krejčí, Petr Kuglík, Henrieta Grešliková, Viera Sandecká, Roman Hájek
Publikováno v:
Haematologica. 99(2)
Even in the era of new drugs, multiple myeloma patients with extramedullary relapse have a poor prognosis. Our goal was to analyze the frequency and outcome of extramedullary relapse occurring in relapsed multiple myeloma patients. In total, we analy