Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Lenka Vecerova"'
Autor:
Martina Slanarova, Zbynek Strasky, Lenka Vecerova, Eva Brcakova, Stanislav Micuda, Jana Rathouska, Petr Nachtigal
Publikováno v:
Journal of Atherosclerosis and Thrombosis. 19:115-126
Aim: Transforming growth factor-beta (TGF-β) plays important role in atherogenesis via TGF-β receptors and Smad proteins, which determine its signaling activity. In this study, we hypothesized, whether non-lipid related effects of atorvastatin, aff
Autor:
Eva Brcakova, Lenka Vecerova, Zbynek Strasky, Martina Slanarova, Zdenka Kudlackova, Jana Rathouska, Petr Nachtigal, Stanislav Micuda, Ctirad Andrys
Publikováno v:
Circulation Journal. 75:1747-1755
Background: The aim of the study was to evaluate whether cholesterol-rich diet affects transforming growth factor-β-RIII (endoglin) levels in blood and 2 endoglin-related pathways in the aorta of ApoE/LDLR double knockout mice. Methods and Results:
Autor:
Stanislav Micuda, Martina Slanarova, Ctirad Andrys, Lenka Vecerova, Zuzana Mullerova, Eva Brcakova, Zbynek Strasky, Jana Rathouska, Petr Nachtigal
Publikováno v:
Pharmacological research. 64(1)
Endoglin (a type III TGF-β receptor) is able to modulate ligand binding and signaling by association with the TGF-β type I receptors (ALK-1 and ALK-5). In this study, we hypothesized whether atorvastatin treatment affects endoglin/ALK-1/p-Smad1/VEG
Publikováno v:
Toxicology Letters. 205:S300
Autor:
Katerina Pospechova, Vladimir Semecky, Nada Pospisilova, Eva Brcakova, Lenka Vecerova, Stanislav Micuda, Petr Nachtigal
Publikováno v:
ResearcherID
Scopus-Elsevier
Scopus-Elsevier
Aim: Endoglin is a homodimeric transmembrane glycoprotein that has been demonstrated to affect transforming growth factor β (TGF-β) signaling and endothelial nitric oxide synthase (eNOS) expression by affecting SMAD proteins in vitro. Thus, in this
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