Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Lenka Valesova"'
Autor:
Mahmoud Al-Obeidallah, Dagmar Jarkovská, Lenka Valešová, Jan Horák, Jan Jedlička, Lukáš Nalos, Jiří Chvojka, Jitka Švíglerová, Jitka Kuncová, Jan Beneš, Martin Matějovič, Milan Štengl
Publikováno v:
Journal of Personalized Medicine, Vol 11, Iss 3, p 164 (2021)
Porcine model of peritonitis-induced sepsis is a well-established clinically relevant model of human disease. Interindividual variability of the response often complicates the interpretation of findings. To better understand the biological basis of t
Externí odkaz:
https://doaj.org/article/89baf77b1e3d459a81b7ff1d9687bdb6
Autor:
Jiri Müller, Jaroslav Radej, Jan Horak, Thomas Karvunidis, Lenka Valesova, Miroslav Kriz, Martin Matejovic
Publikováno v:
Biomedicines, Vol 11, Iss 12, p 3192 (2023)
Almost a quarter of a millennium after the discovery of an acidic substance in sour milk by Swedish chemist Carl Wilhelm Scheele and more than 100 years after the demonstration of a tight connection between this lactic acid and tissue hypoxia in shoc
Externí odkaz:
https://doaj.org/article/49fe5bd1c3014788a6a41ad4b80204dd
Publikováno v:
BMC Nephrology, Vol 18, Iss 1, Pp 1-8 (2017)
Abstract Background Septic acute kidney injury affects 40–50% of all septic patients. Molecular differences between septic patients with and without acute kidney injury (AKI) are only poorly understood. Here, we investigated gene expression changes
Externí odkaz:
https://doaj.org/article/25e98992402d4f549595950fbd906751
Autor:
Jan Benes, Zdenek Tuma, Jiri Moravec, Roman Sykora, Jiri Chvojka, Martin Matejovic, Jan Mares, Lenka Valesova
Publikováno v:
Shock. 46:453-464
Although the burden of septic acute kidney injury continues to increase, the molecular pathogenesis remains largely obscure. The aim of this exploratory study was a discovery-driven analysis of dynamic kidney tissue protein expression changes applied
Autor:
Lukas Nalos, Jan Benes, Vojech Danihel, Vendula Martinkova, Lenka Valesova, Jiri Chvojka, Martin Matejovic
Publikováno v:
Shock (Augusta, Ga.). 53(1)
As controversy persists regarding the benefits of mechanical circulatory support in septic shock with a predominantly vasoplegic phenotype, preclinical studies may provide a useful alternative to fill the actual knowledge gap. Here, we investigated t
Autor:
Lukas Nalos, Jiri Chvojka, Dagmar Jarkovska, Lenka Valesova, Martin Matejovic, Jan Benes, Jitka Sviglerova, Milan Stengl, Vojtech Danihel
Depression of heart-rate variability (HRV) in conditions of systemic inflammation has been shown in both patients and experimental animal models and HRV has been suggested as an early indicator of sepsis. The sensitivity of HRV-derived parameters to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47a00b38ac868dd092ff36030e91d4a4
https://europepmc.org/articles/PMC5407591/
https://europepmc.org/articles/PMC5407591/
Autor:
Zdenek Tuma, Jitka Kuncova, Martina Grundmanova, Michaela Markova, Lenka Valesova, Jiri Chvojka, Martin Matejovic, Jan Benes
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1859:e89-e90
Autor:
Pavel Vintrych, Mahmoud Al-Obeidallah, Jan Horák, Jiří Chvojka, Lenka Valešová, Lukáš Nalos, Dagmar Jarkovská, Martin Matějovič, Milan Štengl
Publikováno v:
Frontiers in Physiology, Vol 13 (2023)
Infectious diseases, which often result in deadly sepsis or septic shock, represent a major global health problem. For understanding the pathophysiology of sepsis and developing new treatment strategies, reliable and clinically relevant animal models
Externí odkaz:
https://doaj.org/article/3068e7baecca4e37a990f4764f68e4c2