Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Lenka Valášková"'
Autor:
Alexandr Hrabálek, Petr Pavek, Pavel Sychra, Oto Pavliš, Lenka Valášková, Kateřina Vávrová, Galina Karabanovich, Hana Vlčková, Jaroslav Roh, Alejandro Carazo, Jiřina Stolaříková, Věra Klimešová, Jan Němeček
Publikováno v:
Bioorganic & Medicinal Chemistry. 25:5468-5476
In this work, four series of tertiary amine-containing derivatives of 3,5-dinitrophenyl tetrazole and oxadiazole antitubercular agents were prepared, and their in vitro antimycobacterial effects were evaluated. We found that the studied compounds sho
Autor:
Jan Němeček, Věra Klimešová, Galina Karabanovich, Jiřina Stolaříková, Alexandr Hrabálek, Jaroslav Roh, Petr Pavek, Klára Konečná, Alejandro Carazo, Kateřina Vávrová, Lenka Valášková, Oto Pavliš
Publikováno v:
European Journal of Medicinal Chemistry. 126:369-383
Two new classes of antitubercular agents, namely 5-alkylsulfanyl-1-(3,5-dinitrophenyl)-1H-tetrazoles and 2-alkylsulfanyl-5-(3,5-dinitrophenyl)-1,3,4-oxadiazoles, and their structure-activity relationships are described. These compounds possessed exce