Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Lenka Kovarova"'
The effect of aminooxy-linkers’ structure on the mechanical properties of hyaluronan-oxime hydrogels
Autor:
Petra Sedova, Radovan Buffa, Tereza Koci, Lenka Kovarova, Jiri Bednarik, Hana Vagnerova, Vladimir Velebny
Publikováno v:
eXPRESS Polymer Letters, Vol 16, Iss 3, Pp 265-278 (2022)
The wide range of hydrogel applications is a result of the optimization of gelation. Herein, the various aminooxylinkers were synthesized to study the kinetics of gelation and mechanical properties of hydrogels prepared by crosslinking of aldehyde-mo
Externí odkaz:
https://doaj.org/article/8ca2861474514385ba9781c1c67727d2
Autor:
Joanne O’Dwyer, Robert Murphy, Arlyng González-Vázquez, Lenka Kovarova, Martin Pravda, Vladimir Velebny, Andreas Heise, Garry P. Duffy, Sally Ann Cryan
Publikováno v:
Pharmaceutics, Vol 13, Iss 6, p 779 (2021)
Heart failure has a five-year mortality rate approaching 50%. Inducing angiogenesis following a myocardial infarction is hypothesized to reduce cardiomyocyte death and tissue damage, thereby preventing heart failure. Herein, a novel nano-in-gel deliv
Externí odkaz:
https://doaj.org/article/a21fcaf49fcc4a58836dddb2d22007ed
Autor:
Joanne O’Dwyer, Megan Cullen, Sarinj Fattah, Robert Murphy, Smiljana Stefanovic, Lenka Kovarova, Martin Pravda, Vladimir Velebny, Andreas Heise, Garry P. Duffy, Sally Ann Cryan
Publikováno v:
Pharmaceutics, Vol 12, Iss 6, p 513 (2020)
Stromal-Derived Factor 1α (SDF) is an angiogenic, chemotactic protein with significant potential for applications in a range of clinical areas, including wound healing, myocardial infarction and orthopaedic regenerative approaches. The 26-min in viv
Externí odkaz:
https://doaj.org/article/d4b1b26ac1bf4e6eb4145cd5301eb376
Autor:
Martin Pravda, Vladimir Velebny, Lenka Kovarova, Sally-Ann Cryan, Joanne O’Dwyer, Arlyng González-Vázquez, Andreas Heise, Robert Murphy, Garry P. Duffy
Publikováno v:
Pharmaceutics
Volume 13
Issue 6
Pharmaceutics. 2021, vol. 13, issue 6, p. 1-19.
Pharmaceutics, Vol 13, Iss 779, p 779 (2021)
Volume 13
Issue 6
Pharmaceutics. 2021, vol. 13, issue 6, p. 1-19.
Pharmaceutics, Vol 13, Iss 779, p 779 (2021)
Heart failure has a five-year mortality rate approaching 50%. Inducing angiogenesis following a myocardial infarction is hypothesized to reduce cardiomyocyte death and tissue damage, thereby preventing heart failure. Herein, a novel nano-in-gel deliv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7c79993c720ce2bea0e0daa690c0af5
Autor:
Robert Murphy, Garry P. Duffy, Sally-Ann Cryan, Joanne O’Dwyer, Sarinj Fattah, Megan Cullen, Lenka Kovarova, Vladimir Velebny, Smiljana Stefanovic, Martin Pravda, Andreas Heise
Publikováno v:
Pharmaceutics
Pharmaceutics, Vol 12, Iss 513, p 513 (2020)
Volume 12
Issue 6
Pharmaceutics, Vol 12, Iss 513, p 513 (2020)
Volume 12
Issue 6
Stromal-Derived Factor 1&alpha
(SDF) is an angiogenic, chemotactic protein with significant potential for applications in a range of clinical areas, including wound healing, myocardial infarction and orthopaedic regenerative approaches. The 26-m
(SDF) is an angiogenic, chemotactic protein with significant potential for applications in a range of clinical areas, including wound healing, myocardial infarction and orthopaedic regenerative approaches. The 26-m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b862a0f20c0700012d16e601f6693fd
https://pubmed.ncbi.nlm.nih.gov/32512712
https://pubmed.ncbi.nlm.nih.gov/32512712
Autor:
Martin Pravda, Ruth E. Levey, Janice O'Sullivan, Fergal J. O'Brien, Garry P. Duffy, Brenton Cavanagh, Thomas Farrell, Vladimir Velebny, Laura Gallagher, Eimear B. Dolan, Lenka Kovarova
The incorporation of the RGD peptide (arginine-glycine-aspartate) into biomaterials has been proposed to promote cell adhesion to the matrix, which can influence and control cell behaviour and function. While many studies have utilised RGD modified b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f58105183fd2b4916f90fe4bbdfbfb8
http://hdl.handle.net/10379/15847
http://hdl.handle.net/10379/15847
Autor:
Eimear B. Dolan, Andreas Heise, Vladimir Velebny, Sally-Ann Cryan, Joanne O’Dwyer, Lenka Kovarova, Garry P. Duffy, Martin Pravda, Robert Murphy
Publikováno v:
Drug delivery and translational research. 10(2)
The 5-year mortality rate for heart failure borders on 50%. The main cause is an ischaemic cardiac event where blood supply to the tissue is lost and cell death occurs. Over time, this damage spreads and the heart is no longer able to pump efficientl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1304bbe14b470795b1524901d81aa9da
https://pubmed.ncbi.nlm.nih.gov/31691161
https://pubmed.ncbi.nlm.nih.gov/31691161
Autor:
Aiden Flanagan, Gabriella Bellavia, Vladimir Velebny, Martin Pravda, Gerard M. Cooney, Stefania Straino, Romana Sulakova, Eimear B. Dolan, Ivana Ščigalková, Dorothee Daro, Garry P. Duffy, Nathalie Braun, Hugh O'Neill, Helena M. Kelly, Bruce P. Murphy, Lenka Kovarova, Brenton Cavanagh
Injectable hydrogels that aim to mechanically stabilise the weakened left ventricle wall to restore cardiac function or to deliver stem cells in cardiac regenerative therapy have shown promising data. However, the clinical translation of hydrogel-bas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eab450e24319bc4267ae9d10213f0e87
http://hdl.handle.net/10379/15190
http://hdl.handle.net/10379/15190
Autor:
Svenja Hinderer, Lenka Kovarova, Nathalie Braun, Peter Dockery, Bruce P. Murphy, M. Hamman de Vaal, Garry P. Duffy, Vladimir Velebny, Gabriella Bellavia, Hugh O'Neill, Martin Pravda, Michael G. Monaghan, Helena M. Kelly, Katja Schenke-Layland, Robert Greensmith, Dorothee Daro, Stefania Straino, Stephen Wildhirt, Ruth E. Levey, Björn Hofmann, Eimear B. Dolan, David S. Monahan
Publikováno v:
Materials scienceengineering. C, Materials for biological applications. 103
The limited regenerative capacity of the heart after a myocardial infarct results in remodeling processes that can progress to congestive heart failure (CHF). Several strategies including mechanical stabilization of the weakened myocardium and regene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d39405c68a980f6df58199dee7a2bdb6
https://pubmed.ncbi.nlm.nih.gov/31349422
https://pubmed.ncbi.nlm.nih.gov/31349422
Autor:
O'Dwyer, Joanne, Murphy, Robert, Dolan, Eimear B., Kovarova, Lenka, Pravda, Martin, Velebny, Vladimir, Heise, Andreas, Duffy, Garry P., Cryan, Sally Ann
Publikováno v:
Drug Delivery & Translational Research; Apr2020, Vol. 10 Issue 2, p440-454, 15p