Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Lenka Daumová"'
Autor:
Lubomír Minařík, Kristýna Pimková, Juraj Kokavec, Adéla Schaffartziková, Fréderic Vellieux, Vojtěch Kulvait, Lenka Daumová, Nina Dusilková, Anna Jonášová, Karina Savvulidi Vargová, Petra Králová Viziová, Radislav Sedláček, Zuzana Zemanová, Tomáš Stopka
Publikováno v:
Cells, Vol 11, Iss 2, p 223 (2022)
The mechanisms by which myelodysplastic syndrome (MDS) cells resist the effects of hypomethylating agents (HMA) are currently the subject of intensive research. A better understanding of mechanisms by which the MDS cell becomes to tolerate HMA and pr
Externí odkaz:
https://doaj.org/article/39a2027bf15f48a4a4b8d8a3b9e6ba32
Autor:
Elena Golovina, Tomas Heizer, Lenka Daumova, Martin Bajecny, Simona Fontana, Valentina Griggio, Rebecca Jones, Marta Coscia, Chiara Riganti, Karina Savvulidi Vargova
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Hypoxia represents one of the key factors that stimulates the growth of leukemic cells in their niche. Leukemic cells in hypoxic conditions are forced to reprogram their original transcriptome, miRNome, and metabolome. How the coupling of mi
Externí odkaz:
https://doaj.org/article/7a94bdf3a2954ff5803329b72cdc9387
Autor:
Věra Kolářová, Jan Pankrác, Pavel Klener, Petr Chytil, Ondřej Lidický, Luděk Šefc, Diana Tuskova, Tomáš Etrych, Lenka Daumová, Eva Pokorná
Publikováno v:
Journal of Controlled Release. 289:44-55
In this study, we report the in vivo anti-lymphoma efficacy and diagnostic potential of newly designed near-infrared fluorescent dye containing polymer-doxorubicin conjugates using murine models of malignant lymphomas including one cell line-derived
Autor:
Lubor Urbánek, Mahmudul Alam, Vladimír Kryštof, Libor Havlíček, Pavel Klener, Miroslav Strnad, Michaela Nekardova, Antonín Šturc, Petr Pachl, Jitka Široká, Pavlína Řezáčová, Jana Škerlová, Miroslav Peřina, Radek Jorda, Tomáš Pospíšil, Lenka Daumová, Diana Tuskova
Publikováno v:
Journal of medicinal chemistry. 62(9)
Cyclin-dependent kinases are therapeutic targets frequently deregulated in various cancers. By convenient alkylation of the 5-sulfanyl group, we synthesized 3-isopropyl-7-[4-(2-pyridyl)benzyl]amino-1(2) H-pyrazolo[4,3- d]pyrimidines with various subs