Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Lenka Bourova"'
Autor:
Petr L. Jedelsky, Zdenka Drastichova, Lenka Bourova, Lucie Hejnova, Petr Svoboda, Jiri Novotny
Publikováno v:
Journal of Cellular Biochemistry. 109:255-264
This study aimed to determine whether sustained stimulation with thyrotropin-releasing hormone (TRH), a peptide with important physiological functions, can possibly affect expression of plasma membrane proteins in HEK293 cells expressing high levels
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7fca83ee5a8144d725dfadd696296953
https://doi.org/10.1002/jcb.22409
https://doi.org/10.1002/jcb.22409
Publikováno v:
Journal of Receptors and Signal Transduction. 27:335-352
We monitored the radioligand-binding characteristics of thyrotropin-releasing hormone (TRH) receptors, functional activity of G(q/11)alpha proteins, and functional status of the whole signaling cascade in HEK293 expressing high levels of TRH receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e369d2b3b7ea2502bc6fa6810562b5e
https://doi.org/10.1080/10799890701684142
https://doi.org/10.1080/10799890701684142
Publikováno v:
Developmental Brain Research. 151:67-73
The number and affinity of GABA(B) receptors (assayed by the specific antagonist [(3)H]CGP54626A) was unchanged when compared in carefully washed cerebrocortical membranes from young (12-day-old) and adult (90-day-old) rats. In contrast, high-affinit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe2a8f9fac0d3ed2dfb4ed49ef78bda9
https://doi.org/10.1016/j.devbrainres.2004.03.014
https://doi.org/10.1016/j.devbrainres.2004.03.014
Autor:
Graeme Milligan, Lenka Bourova, Jiri Novotny, Zuzana Moravcova, Alexandra Kostrnova, Petr Svoboda, Lucie Hejnova, Hyo-Eun Moon
Publikováno v:
Journal of Neurochemistry. 85:34-49
Low-density membrane fragments (domains) were separated from the bulk of plasma membranes of human embryonic kidney (HEK)293 cells expressing a δ-opioid (DOP) receptor-Gi1α fusion protein by drastic homogenization and flotation on equilibrium sucro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b1b8110acd202c287dd285c7287c576
https://doi.org/10.1046/j.1471-4159.2003.01667.x
https://doi.org/10.1046/j.1471-4159.2003.01667.x
Autor:
Kristina Bardova, Filip Baumruk, Jan Kopecký, Petr Svoboda, Jirí Novotný, Pavel Flachs, Ivan Mikšík, Jana Sponarova, Lenka Bourova
Publikováno v:
Biochemical Journal. 364:369-376
In vitro experiments suggest that stimulation of lipolysis by catecholamines in adipocytes depends on the energy status of these cells. We tested whether mitochondrial uncoupling proteins (UCPs) that control the efficiency of ATP production could aff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::590a0359c2accbb14542877c2d8b4ba9
https://doi.org/10.1042/bj20011438
https://doi.org/10.1042/bj20011438
Autor:
Erik A. Johannessen, Peter H. Cobbold, Petr Svoboda, John M. R. Weaver, Jonathan M. Cooper, Lenka Bourova
Publikováno v:
Analytical Chemistry. 74:2190-2197
Current strategies for cell-based screening generally focus on the development of highly specific assays, which require an understanding of the nature of the signaling molecules and cellular pathways involved. In contrast, changes in temperature of c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65e802129396c9846f9ca1fb0c658d81
https://doi.org/10.1021/ac011028b
https://doi.org/10.1021/ac011028b
Publikováno v:
Developmental Brain Research. 133:69-75
Maturation of the brain adenylyl cyclase (AC) signalling system was investigated in the developing rat cortex, thalamus and hippocampus. Expression of AC type II, IV and VI measured by Western blot dramatically increased in all tested brain regions d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2669f6f1e21f66f19e2482e74610afe8
https://doi.org/10.1016/s0165-3806(01)00323-6
https://doi.org/10.1016/s0165-3806(01)00323-6
Publikováno v:
Journal of Molecular Endocrinology. 23:223-229
Levels of guanine nucleotide-binding proteins G(q)alpha and G(11)alpha, which produce receptor regulation of phospholipase C, were measured immunologically in purified plasma membrane fractions of hamster brown adipose tissue (BAT). This was achieved
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f10b42a748c49cdde565b388a849fc7
https://doi.org/10.1677/jme.0.0230223
https://doi.org/10.1677/jme.0.0230223
Autor:
Lenka, Bourova, Miroslava, Vosahlikova, Dmytro, Kagan, Katerina, Dlouha, Jiri, Novotny, Petr, Svoboda
Publikováno v:
Medical science monitor : international medical journal of experimental and clinical research. 16(8)
The functional activity of trimeric guanine-nucleotide-binding proteins (G-proteins) represents an essential step in linking and regulation of the opioid receptor (mu-, delta- and kappa-OR)-initiated signaling pathways. Theoretical basis and/or molec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8bfb34fcf5d22866bda47d479a1b4ef9
https://pubmed.ncbi.nlm.nih.gov/20671607
https://pubmed.ncbi.nlm.nih.gov/20671607
Autor:
Lenka Rezabkova, Tomas Obsil, Veronika Obsilova, Lenka Bourova, Miroslav Šulc, Jaroslav Vecer, Petr Svoboda, Evzen Boura, Petr Herman
Publikováno v:
Journal of structural biology. 170(3)
Regulator of G protein signaling (RGS) proteins function as GTPase-activating proteins (GAPs) for the alpha-subunit of heterotrimeric G proteins. Several RGS proteins have been found to interact with 14-3-3 proteins. The 14-3-3 protein binding inhibi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e7ac9d8f2154b1c62f428cae548b154
https://pubmed.ncbi.nlm.nih.gov/20347994
https://pubmed.ncbi.nlm.nih.gov/20347994