Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Lenka Borská"'
Autor:
Martin Beranek, Pavel Borsky, Zdenek Fiala, Ctirad Andrys, Kvetoslava Hamakova, Marcela Chmelarova, Helena Kovarikova, Adam Karas, Jan Kremlacek, Vladimir Palicka, Lenka Borska
Publikováno v:
Anais Brasileiros de Dermatologia, Vol 98, Iss 1, Pp 68-74 (2023)
Abstract Background The pathogenesis of psoriasis vulgaris involves changes in DNA molecules, genomic instability, telomere attrition, and epigenetic alterations among them. These changes are also considered important mechanisms of aging in cells and
Externí odkaz:
https://doaj.org/article/b97c035914a84297b0a15489066e404f
Autor:
Drahomira Holmannova, Pavel Borsky, Ctirad Andrys, Jan Kremlacek, Zdenek Fiala, Helena Parova, Vit Rehacek, Monika Esterkova, Gabriela Poctova, Tereza Maresova, Lenka Borska
Publikováno v:
Biomedicines, Vol 12, Iss 1, p 242 (2024)
Background: Biological aging is a physiological process that can be altered by various factors. The presence of a chronic metabolic disease can accelerate aging and increase the risk of further chronic diseases. The aim of the study was to determine
Externí odkaz:
https://doaj.org/article/8df5a6c675484401bf9df4a7631b11dd
Autor:
Drahomira Holmannova, Pavel Borsky, Helena Parova, Tereza Stverakova, Milan Vosmik, Libor Hruska, Zdenek Fiala, Lenka Borska
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 20, p 15468 (2023)
Aging is a natural, gradual, and inevitable process associated with a series of changes at the molecular, cellular, and tissue levels that can lead to an increased risk of many diseases, including cancer. The most significant changes at the genomic l
Externí odkaz:
https://doaj.org/article/39808b2978de452881d37a36df064b12
Autor:
Drahomira Holmannova, Pavel Borsky, Ctirad Andrys, Jan Krejsek, Eva Cermakova, Zdenek Fiala, Kvetoslava Hamakova, Tereza Svadlakova, Helena Parova, Vit Rehacek, Gabriela Poctova, Lenka Borska
Publikováno v:
Journal of Personalized Medicine, Vol 12, Iss 12, p 1965 (2022)
Psoriasis and metabolic syndrome (MetS) are chronic inflammatory conditions associated with the dysregulation of immune system reactivity. The inflammatory processes of both diseases have not yet been fully characterized, and the evaluation of protei
Externí odkaz:
https://doaj.org/article/6cac2bfe279441cabcdb235503c61dca
Autor:
Adam Karas, Drahomira Holmannova, Pavel Borsky, Zdenek Fiala, Ctirad Andrys, Kvetoslava Hamakova, Tereza Svadlakova, Vladimir Palicka, Jan Krejsek, Vit Rehacek, Monika Esterkova, Helena Kovarikova, Lenka Borska
Publikováno v:
Biomedicines, Vol 10, Iss 5, p 1133 (2022)
Background: This study aims to investigate potential markers of psoriasis and aging, and to elucidate possible connections between these two processes. Methods: The serum samples of 60 psoriatic patients and 100 controls were analysed, and the levels
Externí odkaz:
https://doaj.org/article/7ae87b8b782441d6b45147f720c94349
Autor:
Drahomira Holmannova, Lenka Borska, Ctirad Andrys, Pavel Borsky, Jan Kremlacek, Kvetoslava Hamakova, Vit Rehacek, Andrea Malkova, Tereza Svadlakova, Vladimir Palicka, Jan Krejsek, Zdenek Fiala
Publikováno v:
Journal of Immunology Research, Vol 2020 (2020)
Background. Psoriasis is a chronic systemic inflammatory disease associated with a wide range of comorbidities, including metabolic syndrome (MetS). Serum calprotectin, ANGPTL8, and oxidative damage to nucleic acids might be associated with both dise
Externí odkaz:
https://doaj.org/article/eb9a966c21b64696b3575619d1a15c10
Autor:
Pavel Borsky, Zdenek Fiala, Ctirad Andrys, Martin Beranek, Kvetoslava Hamakova, Andrea Malkova, Tereza Svadlakova, Jan Krejsek, Vladimir Palicka, Lenka Borska, Vit Rehacek
Publikováno v:
Mediators of Inflammation, Vol 2020 (2020)
Background. Psoriasis vulgaris is a chronic autoimmune disease associated with systemic inflammation. Increased levels of numerous cytokines, chemokines, growth factors, and other molecules were found in the skin and in the circulation of psoriatic p
Externí odkaz:
https://doaj.org/article/4472ece160a54b45a93fc286a8b34df2
Autor:
Simona Vachatova, Ctirad Andrys, Jan Krejsek, Miloslav Salavec, Karel Ettler, Vit Rehacek, Eva Cermakova, Andrea Malkova, Zdenek Fiala, Lenka Borska
Publikováno v:
Journal of Immunology Research, Vol 2016 (2016)
The presented article studies the role of selected inflammatory and anti-inflammatory serum markers of psoriatic patients in the pathogenesis of metabolic syndrome (MS) and psoriasis. The study is based on the comparison between the group of psoriati
Externí odkaz:
https://doaj.org/article/b76e8ec6a29c4b8fa4777f52b0bd14b2
Autor:
Katerina Kondelkova, Lenka Borska, Ctirad Andrys, Jan Krejsek, Kvetoslava Hamakova, Simona Rendarova, Vit Rehacek, Jan Kremlacek, Zdenek Fiala
Publikováno v:
Mediators of Inflammation, Vol 2015 (2015)
Psoriasis is associated with metabolic activity of adipose tissue which produces pro- and anti-inflammatory adipokines. Goeckerman therapy (GT) represents an effective treatment of psoriasis. This study evaluated variation of selected inflammatory an
Externí odkaz:
https://doaj.org/article/8420e9595dc04fd3b5e4d192e8574bf4
Autor:
Lenka Borska, Ctirad Andrys, Jan Krejsek, Vladimir Palicka, Marcela Chmelarova, Kvetoslava Hamakova, Jan Kremlacek, Pavel Borsky, Zdenek Fiala
Publikováno v:
Journal of Immunology Research, Vol 2014 (2014)
Some specific antibodies indicate the presence of antigenic structures on DNA (DNA adducts) that can play an important role in the process of mutagenesis and/or carcinogenesis. They indicate the presence of increased genotoxic potential (hazard) prio
Externí odkaz:
https://doaj.org/article/011c74f412b944ceab163e30dbedec4b