Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Lenka Šmerdová"'
Autor:
Anna Šimonová, Veronika Romanská, Barbora Benoni, Karel Škubník, Lenka Šmerdová, Michaela Procházková, Kristina Spustová, Ondřej Moravčík, Lenka Gahurova, Jan Pačes, Pavel Plevka, Hana Cahová
Publikováno v:
Chembiochem : a European journal of chemical biology. 23(17)
The Picornavirales include viruses that infect vertebrates, insects, and plants. It was believed that they pack only their genomic mRNA in the particles; thus, we envisaged these viruses as excellent model systems for studies of mRNA modifications. W
Autor:
Mária Gondová, T. Fuzik, Lenka Šmerdová, D. Hrebik, Pavel Plevka, Ondrej Šedo, Zbyněk Zdráhal, Athanassios Adamopoulos
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Medical visits and missed days of school and work caused by rhinoviruses cost tens of billions of US dollars annually. Currently, there are no antivirals against rhinoviruses, and the available treatments only treat the symptoms. Here, w
Autor:
Helena Libalova, Lenka Šmerdová, Jana Svobodová, Alois Kozubík, Jiřina Procházková, Martin Krkoška, Markéta Kabátková, Miroslav Machala, Jiří Kléma, Jan Vondráček, Jan Topinka
Publikováno v:
Toxicological Sciences. 172:368-384
The aryl hydrocarbon receptor (AhR) activation has been shown to alter proliferation, apoptosis, or differentiation of adult rat liver progenitors. Here, we investigated the impact of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-mediated AhR activation
Autor:
Jana Moravcová, Lenka Šmerdová, T. Fuzik, Michaela Procházková, Lukáš Sukeník, Antonín Přidal, Robert Vácha, Pavel Plevka, K. Skubnik, David Buchta
Publikováno v:
Science Advances
To enable genome release, capsids of iflaviruses crack into pieces or open like flowers.
The family Iflaviridae includes economically important viruses of the western honeybee such as deformed wing virus, slow bee paralysis virus, and sacbrood v
The family Iflaviridae includes economically important viruses of the western honeybee such as deformed wing virus, slow bee paralysis virus, and sacbrood v
Autor:
Dominik Hrebík, Tibor Füzik, Mária Gondová, Lenka Šmerdová, Athanassios Adamopoulos, Ondrej Šedo, Zbyněk Zdráhal, Pavel Plevka
Publikováno v:
Acta Crystallographica Section A Foundations and Advances. 77:C244-C244
Autor:
Jan Vondráček, Jana Schmuczerova, Jiří Neča, Jana Svobodová, Jan Topinka, Miroslav Machala, Alois Kozubík, Lenka Šmerdová
Publikováno v:
Toxicology. 314:30-38
Long-term deregulated inflammation represents one of the key factors contributing to lung cancer etiology. Previously, we have observed that tumor necrosis factor-α (TNF-α), a major pro-inflammatory cytokine, enhances genotoxicity of benzo[a]pyrene
Autor:
Jiří Kohoutek, Jiří Pacherník, Miroslav Machala, Dominika Sýkorová, Jiřina Procházková, Markéta Kabátková, Alois Kozubík, Eva Hrubá, Pavlína Šimečková, Lenka Šmerdová, Jan Vondráček
Publikováno v:
Toxicological Sciences. 134:258-270
Plakoglobin is an important component of intercellular junctions, including both desmosomes and adherens junctions, which is known as a tumor suppressor. Although mutations in the plakoglobin gene (Jup) and/or changes in its protein levels have been
Autor:
Miroslav Machala, Eva Hrubá, Dagmar Faust, Jiřina Procházková, Lenka Šmerdová, Pavel Krčmář, Petra Hulinková, Bernd Kaina, Cornelia Dietrich, Jan Vondráček
Publikováno v:
Archives of Toxicology
Although the tumor-promoting effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), coplanar polychlorinated biphenyls (PCBs), and related compounds in liver tissue are primarily attributed to the activation of the aryl hydrocarbon receptor (AhR), th
Autor:
Jiřina Procházková, Jan Topinka, Jana Svobodová, Miroslav Machala, Helena Libalova, Jan Vondráček, Lenka Šmerdová
Publikováno v:
Toxicology Letters. 280:S132-S133
Autor:
Zdeněk Dvořák, Markéta Kabátková, Petra Brenerová, Jana Svobodová, Lenka Šmerdová, Miroslav Machala, Jan Vondráček
Publikováno v:
Toxicology. 333
Inhibition of apoptosis by the ligands of the aryl hydrocarbon receptor (AhR) has been proposed to play a role in their tumor promoting effects on liver parenchymal cells. However, little is presently known about the impact of toxic AhR ligands, such