The Manufacture of Xeno- and Feeder-Free Clinical-Grade Human Embryonic Stem Cell Lines: First Step for Cell Therapy

Autor: Tereza Souralova, Daniela Rehakova, Michal Jeseta, Lenka Tesarova, Jindrich Beranek, Pavel Ventruba, Ales Hampl, Irena Koutna

Publikováno v: International Journal of Molecular Sciences; Volume 23; Issue 20; Pages: 12500

Human embryonic stem cells (hESCs) are increasingly used in clinical trials as they can change the outcome of treatment for many human diseases. They are used as a starting material for further differentiation into specific cell types and to achieve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf9800f7d1e2c298e90b0edd1cd79c24

Characterization of Clinical-Grade Stem Cells: Microscopic, Cellular, Molecular, and Functional Characterization of Stem Cells and Their Products According to Regulatory Requirements for FDA Approval

Autor: Tereza Souralova, Daniela Rehakova, Lenka Tesarova, Ales Hampl, Irena Koutna

Publikováno v: Stem Cell Production ISBN: 9789811675881

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d128e49127836363aa8962c79adac458
https://doi.org/10.1007/978-981-16-7589-8_8

FiloGen: A Model-Based Generator of Synthetic 3-D Time-Lapse Sequences of Single Motile Cells With Growing and Branching Filopodia

Autor: Katsiarina Morgaenko, Vladimír Ulman, Martin Maška, Lívia Eiselleová, David Svoboda, Igor Peterlik, Lenka Tesarova, Tereza Nečasová, Dmitry V. Sorokin

Publikováno v: IEEE Transactions on Medical Imaging
IEEE Transactions on Medical Imaging, Institute of Electrical and Electronics Engineers, 2018, pp.1-12. ⟨10.1109/TMI.2018.2845884⟩
IEEE Transactions on Medical Imaging, 2018, pp.1-12. ⟨10.1109/TMI.2018.2845884⟩

International audience; The existence of diverse image datasets accompanied by reference annotations is a crucial prerequisite for an objective benchmarking of bioimage analysis methods. Nevertheless, such a prerequisite is arduous to satisfy for tim

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ee00412bccdd938ab506130eacf2982
https://doi.org/10.1109/tmi.2018.2845884

Reprogramming of Adult Peripheral Blood Cells into Human Induced Pluripotent Stem Cells as a Safe and Accessible Source of Endothelial Cells

Autor: Daniela Rehakova, Petr Matula, Lenka Tesarova, Irena Koutná, Simon Farkas, Pavel Matula, Katerina Kutalkova, Barbara Šalingová, Eva Vavreckova, Pavel Šimara, Lenka Veverková

Publikováno v: Stem Cells and Development

New approaches in regenerative medicine and vasculogenesis have generated a demand for sufficient numbers of human endothelial cells (ECs). ECs and their progenitors reside on the interior surface of blood and lymphatic vessels or circulate in periph

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f0f57848785d7e88b4838eb63a162c1
https://pubmed.ncbi.nlm.nih.gov/29117787

Differential effects of insulin and dexamethasone on pulmonary surfactant-associated genes and proteins in A549 and H441 cells and lung tissue

Autor: Oldrich Coufal, Pavel Šimara, Lenka Tesarova, Zdenek Rucka, Petr Vanhara, Ivan Čapov, Václav Zvoníček, Stanislav Stejskal, Jan Dolezel, Irena Koutná, Michaela Potesilova

Publikováno v: International Journal of Molecular Medicine. 32:211-218

In this study, the effects of insulin and dexamethasone on the expression and mRNA transcription of 4 pulmonary surfactant-associated proteins [surfactant protein (SFTP)A, SFTPB, SFTPC and SFTPD] were examined. The commercially available cell lines,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74fdec4eff1595a4c07a3680519ac91f
https://doi.org/10.3892/ijmm.2013.1363