Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Lenka, Novakova"'
Autor:
Igal Rosenstein, Lenka Novakova, Hlin Kvartsberg, Anna Nordin, Sofia Rasch, Elzbieta Rembeza, Sofia Sandgren, Clas Malmeström, Stefanie Fruhwürth, Markus Axelsson, Kaj Blennow, Henrik Zetterberg, Jan Lycke
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-12 (2024)
Abstract Background The Gas6/TAM (Tyro3, Axl, and Mer) receptor system has been implicated in demyelination and delayed remyelination in experimental animal models, but data in humans are scarce. We aimed to investigate the role of Gas6/TAM in neurod
Externí odkaz:
https://doaj.org/article/03a9f4ad029b4835b686b9955f7699c1
Autor:
Lenka Novakova, Anna Karin Hedström, Markus Axelsson, Anne Frandsen Brandt, Lars Alfredsson, Tomas Olsson, Jan Lycke
Publikováno v:
Brain and Behavior, Vol 14, Iss 3, Pp n/a-n/a (2024)
Abstract Background A significant proportion of individuals with suspicious onset of multiple sclerosis (MS) does not fulfill the diagnostic criteria. Although some receive other diagnoses, many remain undiagnosed and lack healthcare follow‐up. Thi
Externí odkaz:
https://doaj.org/article/fc59ed666d324f91830d1944a59b9bee
Autor:
Sofia Sandgren, Lenka Novakova, Anna Nordin, Markus Axelsson, Clas Malmeström, Henrik Zetterberg, Jan Lycke
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
BackgroundAlemtuzumab (ALZ) is a pulsed immune reconstitution therapy for multiple sclerosis (MS).ObjectiveTo assess basic characteristics, therapeutic effects, and prognostic biomarkers on clinical and imaging parameters of disease activity for rela
Externí odkaz:
https://doaj.org/article/1a51aa49d87b4da59edc2051d2fd6490
Autor:
Sofia Sandgren, Lenka Novakova, Markus Axelsson, Firoozeh Amirbeagi, Ingrid Kockum, Tomas Olsson, Clas Malmestrom, Jan Lycke
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
BackgroundAlemtuzumab (ALZ) is an immune reconstitution therapy for treating relapsing-remitting multiple sclerosis (RRMS). However, ALZ increases the risk of secondary autoimmune diseases (SADs).ObjectiveWe explored whether the detection of autoimmu
Externí odkaz:
https://doaj.org/article/57d02a89c1f745458ba0c6a29dfd6ed3
Autor:
Igal Rosenstein, Markus Axelsson, Lenka Novakova, Sofia Rasch, Kaj Blennow, Henrik Zetterberg, Jan Lycke
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundEvolving evidence suggests that measurement of cerebrospinal fluid (CSF) kappa free light chain (KFLC) synthesis has high diagnostic sensitivity and specificity for multiple sclerosis (MS), but its prognostic ability is less investigated. T
Externí odkaz:
https://doaj.org/article/22580cb307b44a869eff8346adbec0e9
Autor:
Igal Rosenstein, Sofia Rasch, Markus Axelsson, Lenka Novakova, Kaj Blennow, Henrik Zetterberg, Jan Lycke
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundEmerging evidence supports that determination of intrathecal immunoglobulin M (IgM) synthesis (ITMS) and neurofilament light (NfL) concentration in cerebrospinal fluid (CSF) may be clinically useful as disease severity biomarkers in relapsi
Externí odkaz:
https://doaj.org/article/b3805a9ddeac443699809381360d79eb
Autor:
Nicholas J. Ashton, Shorena Janelidze, Ahmad Al Khleifat, Antoine Leuzy, Emma L. van der Ende, Thomas K. Karikari, Andrea L. Benedet, Tharick A. Pascoal, Alberto Lleó, Lucilla Parnetti, Daniela Galimberti, Laura Bonanni, Andrea Pilotto, Alessandro Padovani, Jan Lycke, Lenka Novakova, Markus Axelsson, Latha Velayudhan, Gil D. Rabinovici, Bruce Miller, Carmine Pariante, Naghmeh Nikkheslat, Susan M. Resnick, Madhav Thambisetty, Michael Schöll, Gorka Fernández-Eulate, Francisco J. Gil-Bea, Adolfo López de Munain, Ammar Al-Chalabi, Pedro Rosa-Neto, Andre Strydom, Per Svenningsson, Erik Stomrud, Alexander Santillo, Dag Aarsland, John C. van Swieten, Sebastian Palmqvist, Henrik Zetterberg, Kaj Blennow, Abdul Hye, Oskar Hansson
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Cerebrospinal fluid neurofilament light (NfL) is a biomarker for neurodegeneration that can also be assessed in blood. Here the authors show in a validation study the potential for plasma NfL as a biomarker for several neurodegenerative diseases.
Externí odkaz:
https://doaj.org/article/5a53b0a732414b4ca05246e46c25baa3
Autor:
Pavla Vasicova, Mark Rinnerthaler, Danusa Haskova, Lenka Novakova, Ivana Malcova, Michael Breitenbach, Jiri Hasek
Publikováno v:
Microbial Cell, Vol 3, Iss 5, Pp 206-214 (2016)
Actin filaments form cortical patches and emanating cables in fermenting cells of Saccharomyces cerevisiae. This pattern has been shown to be depolarized in glucose-depleted cells after formaldehyde fixation and staining with rhodamine-tagged phalloi
Externí odkaz:
https://doaj.org/article/debee9fd75584d55a0bb7ecdcc1c4c51
Autor:
Lenka Novakova, Markus Axelsson, Clas Malmeström, Henrik Imberg, Olle Elias, Henrik Zetterberg, Olle Nerman, Jan Lycke
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0194828 (2018)
Neurodegeneration occurs during the early stages of multiple sclerosis. It is an essential, devastating part of the pathophysiology. Tools for measuring the degree of neurodegeneration could improve diagnostics and patient characterization.This study
Externí odkaz:
https://doaj.org/article/0b948e9eff2041baba3127d71258438e
Publikováno v:
SWS International Scientific Conferences on SOCIAL SCIENCES - ISCSS.
The purpose of the research was to find out whether social service workers perceive close clients as dependent on the care provided. The so-called phenomenon of power and powerlessness can arise from this. We found out whether they are aware that the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c506801a0722e47fa2cd583d47027609
https://doi.org/10.35603/sws.iscss.2022/s07.071
https://doi.org/10.35603/sws.iscss.2022/s07.071