Výsledky vyhledávání - "Lenisa Geron"

Dissertation/ Thesis

Estudo da modulação da via Wnt pelo inibidor de Aurora-quinases AMG900 em linhagens celulares de meduloblastoma pediátrico

Autor: Lenisa Geron

Publikováno v: Biblioteca Digital de Teses e Dissertações da USPUniversidade de São PauloUSP.

O meduloblastoma (MB) é o tumor cerebral maligno mais comum na infância. A formação/progressão desta neoplasia foi associada a alterações moleculares, que inclui a desregulação da via de sinalização Wingless (Wnt), responsável pelo desenv

Externí odkaz: http://www.teses.usp.br/teses/disponiveis/17/17135/tde-04012017-095955/

Zobrazit plný text záznamu

Clinical Prognostic Implications of Wnt Hub Genes Expression in Medulloblastoma

Autor: Andrea Martins-da-Silva, Mirella Baroni, Karina Bezerra Salomão, Pablo Ferreira das Chagas, Ricardo Bonfim-Silva, Lenisa Geron, Gustavo Alencastro Veiga Cruzeiro, Wilson Araújo da Silva, Carolina Alves Pereira Corrêa, Carlos Gilberto Carlotti, Rosane Gomes de Paula Queiroz, Suely Kazue Nagahashi Marie, Silvia Regina Brandalise, José Andrés Yunes, Carlos Alberto Scrideli, Elvis Terci Valera, Luiz Gonzaga Tone

Publikováno v: Cellular and Molecular Neurobiology. 43:813-826

Medulloblastoma is the most common type of pediatric malignant primary brain tumor, and about one-third of patients die due to disease recurrence and most survivors suffer from long-term side effects. MB is clinically, genetically, and epigenetically

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce78ef262243f15ae371e38e4799b959
https://doi.org/10.1007/s10571-022-01217-4

Zobrazit plný text záznamu

Aberrantly expressed microRNAs and their implications in childhood central nervous system tumors

Autor: María Sol Brassesco, Mirella Baroni, Carolina Alves Pereira, Lenisa Geron, Julia Alejandra Pezuk, Karina Bezerra Salomão

Publikováno v: Cancer and Metastasis Reviews. 38:813-828

Even though the treatment of childhood cancer has evolved significantly in recent decades, aggressive central nervous system (CNS) tumors are still a leading cause of morbidity and mortality in this population. Consequently, the identification of mol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90a7c24f063810928f9a80061592e4e3
https://doi.org/10.1007/s10555-019-09820-6

Zobrazit plný text záznamu

The DNA methyltransferase inhibitor zebularine exerts antitumor effects and reveals BATF2 as a poor prognostic marker for childhood medulloblastoma

Autor: Angel Mauricio Castro-Gamero, Luciano Neder, Augusto Faria Andrade, Lenisa Geron, Veridiana Kiill Suazo, Carolina Alves Pereira Corrêa, Simone dos Santos Aguiar, Kleiton Silva Borges, Elton J R Vasconcelos, José Andrés Yunes, Carlos Alberto Scrideli, Ricardo Santos de Oliveira, Luiz Gonzaga Tone

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Medulloblastoma (MB) is the most common solid tumor among pediatric patients and corresponds to 20 % of all pediatric intracranial tumors in this age group. Its treatment currently involves significant side effects. Epigenetic changes such as DNA met

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1132be83b0dddb529ad4cfc972301a40
https://doi.org/10.1007/s10637-016-0401-4

Zobrazit plný text záznamu

Estudo da modulação da via Wnt pelo inibidor de Aurora-quinases AMG900 em linhagens celulares de meduloblastoma pediátrico

Autor: Lenisa Geron

Publikováno v: Biblioteca Digital de Teses e Dissertações da USP
Universidade de São Paulo (USP)
instacron:USP

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0508587ef0fa4c2fd5d76e24c28dc8db
https://doi.org/10.11606/d.17.2017.tde-04012017-095955

Zobrazit plný text záznamu

Molecular characterization of Wnt pathway and function of β-catenin overexpression in medulloblastoma cell lines

Autor: Augusto Faria Andrade, Carolina Alves Pereira Corrêa, Lenisa Geron, Karina Bezerra Salomão, Kleiton Silva Borges, Luiz Gonzaga Tone, Carlos Alberto Scrideli

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Medulloblastoma (MB) is the most common malignant childhood brain tumor. MB is currently classified into four molecular subgroups (Wnt, Shh, Group 3, and Group 4). The wingless (Wnt) pathway is responsible for embryonic development and is deregulated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8b36cf8b8eb74b1093ff7c8cdc3e658

Zobrazit plný text záznamu

Reduced hydroxymethylation characterizes medulloblastoma while TET and IDH genes are differentially expressed within molecular subgroups

Autor: Daniel Antunes Moreno, Silvia Regina Brandalise, Karina Bezerra Salomão, Fernando Silva Ramalho, Luiz Gonzaga Tone, Rosane Gomes de Paula Queiroz, José Andrés Yunes, Ricardo Bonfim-Silva, Luciano Neder Serafini, Carlos Alberto Scrideli, Fabiano Pinto Saggioro, Izilda Aparecida Cardinalli, Lenisa Geron, Simone dos Santos Aguiar, Gustavo Alencastro Veiga Cruzeiro, María Sol Brassesco

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Medulloblastoma (MB) is an embryonal tumour that originates from genetic deregulation of cerebellar developmental pathways and is classified into 4 molecular subgroups: SHH, WNT, group 3, and group 4. Hydroxymethylation levels progressively increases

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3031020a6d449cee6f91ed2503bc20d2
https://pubmed.ncbi.nlm.nih.gov/29582271

Zobrazit plný text záznamu

Erratum to: The DNA methyltransferase inhibitor zebularine exerts antitumor effects and reveals BATF2 as a poor prognostic marker for childhood medulloblastoma

Autor: Simone dos Santos Aguiar, Kleiton Silva Borges, Augusto Faria Andrade, Luciano Neder, Lenisa Geron, Carolina Alves Pereira Corrêa, Veridiana Kiill Suazo, Luiz Gonzaga Tone, Angel Mauricio Castro-Gamero, Ricardo Santos de Oliveira, Elton J R Vasconcelos, José Andrés Yunes, Carlos Alberto Scrideli

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bd2ed29d04a559a24d035ce08b3c94d

Zobrazit plný text záznamu

Antitumour activity of AMG 900 alone or in combination with histone deacetylase inhibitor SaHa on medulloblastoma cell lines

Autor: Augusto Faria Andrade, Luiz Gonzaga Tone, Kleiton Silva Borges, Veridiana K. Suazo, Lenisa Geron, Carlos Alberto Scrideli

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Medulloblastoma (MB) is the most common malignant childhood brain tumour. Aurora kinases are essential for cell division and are primarily active during mitosis. Recently, the combination of aurora kinases inhibitors (iAURK) and histone deacetylase i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8938374c5dc2d96267d5f089a8b8c244
https://pubmed.ncbi.nlm.nih.gov/26000978

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání