Zobrazeno 1 - 10
of 435
pro vyhledávání: '"Lenhof Hans-Peter"'
Autor:
Küntzer Jan, Blum Torsten, Gerasch Andreas, Backes Christina, Hildebrandt Andreas, Kaufmann Michael, Kohlbacher Oliver, Lenhof Hans-Peter
Publikováno v:
Journal of Integrative Bioinformatics, Vol 3, Iss 2, Pp 148-161 (2006)
Recent years have seen an explosive growth in the amount of biochemical data available. Numerous databases have been established and are being used as an essential resource by biologists around the world. The sheer amount and heterogeneity of these d
Externí odkaz:
https://doaj.org/article/650ee2bcfa024d988d9451093bbe08c6
Autor:
Schmitt Jana, Backes Christina, Nourkami-Tutdibi Nasenien, Leidinger Petra, Deutscher Stephanie, Beier Markus, Gessler Manfred, Graf Norbert, Lenhof Hans-Peter, Keller Andreas, Meese Eckart
Publikováno v:
BMC Genomics, Vol 13, Iss 1, p 379 (2012)
Abstract Background Blood-born miRNA signatures have recently been reported for various tumor diseases. Here, we compared the miRNA signature in Wilms tumor patients prior and after preoperative chemotherapy according to SIOP protocol 2001. Results W
Externí odkaz:
https://doaj.org/article/a6d9f04f620e4f42a40eba8051296268
Autor:
Laczny Cedric, Leidinger Petra, Haas Jan, Ludwig Nicole, Backes Christina, Gerasch Andreas, Kaufmann Michael, Vogel Britta, Katus Hugo A, Meder Benjamin, Stähler Cord, Meese Eckart, Lenhof Hans-Peter, Keller Andreas
Publikováno v:
BMC Bioinformatics, Vol 13, Iss 1, p 36 (2012)
Abstract Background Expression profiling provides new insights into regulatory and metabolic processes and in particular into pathogenic mechanisms associated with diseases. Besides genes, non-coding transcripts as microRNAs (miRNAs) gained increasin
Externí odkaz:
https://doaj.org/article/7f682b3a5ec74304896b40187314e0bc
Autor:
Keller Andreas, Hoffmann Jana, Harz Christian, Leidinger Petra, Ludwig Nicole, Backes Christina, Meese Eckart, Lenhof Hans-Peter
Publikováno v:
BMC Genomics, Vol 12, Iss 1, p 340 (2011)
Abstract Background Autoantibodies against self-antigens have been associated not only with autoimmune diseases, but also with cancer and are even found in healthy individuals. The mechanism causing the autoantibody response remains elusive for the m
Externí odkaz:
https://doaj.org/article/1e27eb9c739144fbaf96e844a942491e
Publikováno v:
BMC Medical Genomics, Vol 4, Iss 1, p 43 (2011)
Abstract Background Cancer is a disease of genome alterations that arise through the acquisition of multiple somatic DNA sequence mutations. Some of these mutations can be critical for the development of a tumor and can be useful to characterize tumo
Externí odkaz:
https://doaj.org/article/6065a48f81184fd8896dd7bb0830573d
Autor:
Lenhof Hans-Peter, Philippar Katrin, Backes Christina, Keller Andreas, Schuler Mara, Bauer Petra
Publikováno v:
BMC Plant Biology, Vol 11, Iss 1, p 87 (2011)
Abstract Background High-throughput technologies have opened new avenues to study biological processes and pathways. The interpretation of the immense amount of data sets generated nowadays needs to be facilitated in order to enable biologists to ide
Externí odkaz:
https://doaj.org/article/60cb70c475214133bb739689ab259e0a
Autor:
Stöckel Daniel, Moll Andreas, Toussaint Nora C, Schumann Marcel, Bertsch Andreas, Rurainski Alexander, Dehof Anna, Hildebrandt Andreas, Nickels Stefan, Mueller Sabine C, Lenhof Hans-Peter, Kohlbacher Oliver
Publikováno v:
BMC Bioinformatics, Vol 11, Iss 1, p 531 (2010)
Abstract Background The Biochemical Algorithms Library (BALL) is a comprehensive rapid application development framework for structural bioinformatics. It provides an extensive C++ class library of data structures and algorithms for molecular modelin
Externí odkaz:
https://doaj.org/article/2aaa700e93fc423d933b3bc2925b9539
Autor:
Rass Knuth, Reichrath Jörg, Borries Anne, Keller Andreas, Leidinger Petra, Jager Sven U, Lenhof Hans-Peter, Meese Eckart
Publikováno v:
BMC Cancer, Vol 10, Iss 1, p 262 (2010)
Abstract Background MicroRNA (miRNA) signatures are not only found in cancer tissue but also in blood of cancer patients. Specifically, miRNA detection in blood offers the prospect of a non-invasive analysis tool. Methods Using a microarray based app
Externí odkaz:
https://doaj.org/article/594d8a15925240468c8a8ba825c78114
Autor:
Stephan Bernhard, Stoelben Erich, Wolf Jürgen, Staratschek-Jox Andrea, Andres Claudia, Klein Veronika, Rheinheimer Stefanie, Ludwig Nicole, Heisel Sabrina, Keller Andreas, Leidinger Petra, Stehle Ingo, Hamacher Jürg, Huwer Hanno, Lenhof Hans-Peter, Meese Eckart
Publikováno v:
Respiratory Research, Vol 11, Iss 1, p 18 (2010)
Abstract Background Lung cancer is a very frequent and lethal tumor with an identifiable risk population. Cytological analysis and chest X-ray failed to reduce mortality, and CT screenings are still controversially discussed. Recent studies provided
Externí odkaz:
https://doaj.org/article/160a059e1e2145ed942d135caa6e78b6
Autor:
Huwer Hanno, Scheffler Matthias, Wucherpfennig Frank, Wendschlag Anke, Borries Anne, Leidinger Petra, Keller Andreas, Lenhof Hans-Peter, Meese Eckart
Publikováno v:
BMC Cancer, Vol 9, Iss 1, p 353 (2009)
Abstract Background Deregulated miRNAs are found in cancer cells and recently in blood cells of cancer patients. Due to their inherent stability miRNAs may offer themselves for blood based tumor diagnosis. Here we addressed the question whether there
Externí odkaz:
https://doaj.org/article/9611015a9e5742afbb3371dabf1f5b5c