Zobrazeno 1 - 10
of 250
pro vyhledávání: '"Lenhard, Rudolph"'
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-2 (2024)
Externí odkaz:
https://doaj.org/article/9a909fff3228488aa7304f9893e31407
Autor:
Omid Omrani, Anna Krepelova, Seyed Mohammad Mahdi Rasa, Dovydas Sirvinskas, Jing Lu, Francesco Annunziata, George Garside, Seerat Bajwa, Susanne Reinhardt, Lisa Adam, Sandra Käppel, Nadia Ducano, Daniela Donna, Alessandro Ori, Salvatore Oliviero, Karl Lenhard Rudolph, Francesco Neri
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract The influence of aging on intestinal stem cells and their niche can explain underlying causes for perturbation in their function observed during aging. Molecular mechanisms for such a decrease in the functionality of intestinal stem cells du
Externí odkaz:
https://doaj.org/article/8d8b248d97c8482fa9a842f1ea32364e
Publikováno v:
BMC Biology, Vol 21, Iss 1, Pp 1-12 (2023)
Abstract Background Methods for the long-term in situ transduction of the unperturbed murine intestinal epithelium have not been developed in past research. Such a method could speed up functional studies and screens to identify genetic factors influ
Externí odkaz:
https://doaj.org/article/33b2e89d547c4e1a91b000ef317c7a21
Publikováno v:
Redox Biology, Vol 63, Iss , Pp 102725- (2023)
Dietary restriction (DR) is the most powerful intervention to enhance health and lifespan across species. However, recent findings indicate that DR started in late life has limited capacity to induce health benefits. Age-dependent changes that impair
Externí odkaz:
https://doaj.org/article/ba00ada19cd340e9883c02ad0cb53e7d
Autor:
Jana I. Solomun, Liam Martin, Prosper Mapfumo, Elisabeth Moek, Elias Amro, Friedrich Becker, Stefan Tuempel, Stephanie Hoeppener, K. Lenhard Rudolph, Anja Traeger
Publikováno v:
Journal of Nanobiotechnology, Vol 20, Iss 1, Pp 1-17 (2022)
Abstract Cationic non-viral vectors show great potential to introduce genetic material into cells, due to their ability to transport large amounts of genetic material and their high synthetic versatility. However, designing materials that are effecti
Externí odkaz:
https://doaj.org/article/ac8763d1ebac4c56bbc35c6a64eaf456
Autor:
Maria Thürmer, André Gollowitzer, Helmut Pein, Konstantin Neukirch, Elif Gelmez, Lorenz Waltl, Natalie Wielsch, René Winkler, Konstantin Löser, Julia Grander, Madlen Hotze, Sönke Harder, Annika Döding, Martina Meßner, Fabiana Troisi, Maximilian Ardelt, Hartmut Schlüter, Johanna Pachmayr, Óscar Gutiérrez-Gutiérrez, Karl Lenhard Rudolph, Kathrin Thedieck, Ulrike Schulze-Späte, Cristina González-Estévez, Christian Kosan, Aleš Svatoš, Marcel Kwiatkowski, Andreas Koeberle
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-21 (2022)
Fatty acid unsaturation by stearoyl-CoA desaturase 1 (SCD1) protects against cellular stress through unclear mechanisms. Here the authors show 1,2-dioleoyl-sn-glycero-3-phospho-(1’-myo-inositol) is an SCD1-derived signaling lipid that regulates str
Externí odkaz:
https://doaj.org/article/8fff1ccb32314909871bbf27bc179a32
Autor:
Omid Omrani, Anna Krepelova, Seyed Mohammad Mahdi Rasa, Dovydas Sirvinskas, Jing Lu, Francesco Annunziata, George Garside, Seerat Bajwa, Susanne Reinhardt, Lisa Adam, Sandra Käppel, Nadia Ducano, Daniela Donna, Alessandro Ori, Salvatore Oliviero, Karl Lenhard Rudolph, Francesco Neri
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/e06ca408d7a64681aa20ea29601b042a
Autor:
Silke D. Werle, Nensi Ikonomi, Julian D. Schwab, Johann M. Kraus, Felix M. Weidner, K. Lenhard Rudolph, Astrid S. Pfister, Rainer Schuler, Michael Kühl, Hans A. Kestler
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 1603-1617 (2022)
Controlling phenotypical landscapes is of vital interest to modern biology. This task becomes highly demanding because cellular decisions involve complex networks engaging in crosstalk interactions. Previous work on control theory indicates that smal
Externí odkaz:
https://doaj.org/article/d0b5b7f5c42942bfa222393dd1bb697b
Autor:
Yulin Chen, K. Lenhard Rudolph
Publikováno v:
Haematologica, Vol 106, Iss 6 (2020)
Externí odkaz:
https://doaj.org/article/d2c7b97529db414888f9e51ccb951967
Autor:
Nadja Gebert, Chia-Wei Cheng, Joanna M. Kirkpatrick, Domenico Di Fraia, Jina Yun, Patrick Schädel, Simona Pace, George B. Garside, Oliver Werz, K. Lenhard Rudolph, Henri Jasper, Ömer H. Yilmaz, Alessandro Ori
Publikováno v:
Cell Reports, Vol 31, Iss 4, Pp - (2020)
Summary: The small intestine is responsible for nutrient absorption and one of the most important interfaces between the environment and the body. During aging, changes of the epithelium lead to food malabsorption and reduced barrier function, thus i
Externí odkaz:
https://doaj.org/article/6ec250b7c1924a2c8eabf6e16788b454