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Temperature is one of the main parameters influencing CO2 properties during storage in saline aquifers, since it controls along with pressure the phase behavior of the CO2/brine mixture. When CO2 replaces brine as a free gas it is known to affect the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::418d8ff2ca39b8fea096be47063b9d05
http://gfzpublic.gfz-potsdam.de/pubman/item/escidoc:838936

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IDH 1/2 mutations in astrocytomas WHO grade II: association with localization and seizure as initial symptom

Autor: Stockhammer, F., Misch, M., Helms, H.J., Lengler, U., Prall, F., Deimling, A.V., Hartmann, C.

Publikováno v: 63. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), Joint Meeting mit der Japanischen Gesellschaft für Neurochirurgie (JNS); 20120613-20120616; Leipzig; DOCFR.01.01 /20120604/

Objective: Seizures are the most common initial symptom in patients with low-grade gliomas and strongly depend on the site of the tumour. The majority of low-grade gliomas reveal mutations in the genes encoding isocitrate-dehydrogenase 1 (IDH1) or 2

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12be9ae2bfdcc212c49bd3801fcb88f9

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Cerebral Nicotinic Acetylcholine Receptors (nAChRs) In Early Alzheimer’s Disease (AD) Assessed With The New Radioligand [18F]Flubatine and PET

Autor: Sabri, O., Wilke, S., Graef, S., Lengler, U., Schoenknecht, P., Gertz, H., Becker, G., Luthardt, J., Patt, M., Hesse, S., Barthel, H., Wagenknecht, G., Hoepping, A., Hegerl, U., Brust, P.

Publikováno v: EANM'12-Annual Congress of the European Association of Nuclear Medicine, 27.-31.10.2012, Milan, Italy
European Journal of Nuclear Medicine and Molecular Imaging 39(2012), S221

Objectives: There is evidence from post-mortem studies that the loss of nAChRs, in particular of the alpha4beta2-nAChR, which is obviously most severely reduced at the onset of AD, is a major contributor to the cognitive deterioration in AD. Accordin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::4cb939b3e7c66451335fca56dc82abd7
https://www.hzdr.de/publications/Publ-18022-1

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First in man study with the new radioligand F-18-Flubatine to image alpha4beta2 cerebral nicotinic acetylcholine receptors (nAChRs) in early Alzheimer's disease (AD) with PET

Autor: Sabri, O., Wilke, S., Gräf, S., Lengler, U., Gertz, H. J., Schönknecht, P., Habermann, B., Becker, G., Luthardt, J., Patt, M., Kendziorra, K., Meyer, P., Hesse, S., Barthel, H., Steinbach, J., Wagenknecht, G., Höpping, A., Hegerl, U., Brust, P.

Publikováno v: Nuklearmedizin 51(2012), V77
NuklearMedizin 2012, 25.-28.04.2012, Bremen, Deutschland

Ziel/Aim: Using F-18-A85380 (2FA) PET we recently demonstrated significant cerebral nAChR declines in early AD which correlated significantly with the loss of cognitive function (1-2). However, 2FA is not well suited in clinical routine use because o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::06a099655bea091a9ca449e712b13b8a
https://www.hzdr.de/publications/Publ-16915-2

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