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Autor:
Zhi-Qiang Ling, Peishi Chen, Lian-Lian Hong, Xuan-Yu Hu, Celestial T. Yap, Qi Hao, Han-Ming Shen, Yi Ren, Mingzhu Tang, Boon-Huat Bay, Jiaqing Chen, Leng-Kuan Cheong
Publikováno v:
Free Radical Biology and Medicine. 166:128-139
The liver kinase B1 (LKB1) is an important tumor suppressor and its loss-of-function mutations are observed in around 16% of non-small cell lung cancer (NSCLC) cases. One of the main functions of LKB1 is to activate AMP-activated protein kinase (AMPK