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Autor:
Kirsten Anderson, My My Trinh, Suzanne F. Jones, David Porubek, Serina Warner, Jean-Francois Marier, Leng Pheng, Howard A. Burris
Publikováno v:
Journal of Pharmaceutical Sciences. 100:4536-4545
SN2310 is an injectable emulsion composed of vitamin E, a succinate derivative, as well as 7-ethyl-10-hydroxycamptothecin (SN-38), the active metabolite of irinotecan. Single intravenous doses of 15, 20, 25, and 30 mg/m2 of SN2310 emulsion were admin