Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Lene Meldgaard Knudsen"'
Autor:
Nicolai Grønne Jørgensen, Uffe Klausen, Jacob Handlos Grauslund, Carsten Helleberg, Thomas Granum Aagaard, Trung Hieu Do, Shamaila Munir Ahmad, Lars Rønn Olsen, Tobias Wirenfeldt Klausen, Marie Fredslund Breinholt, Morten Hansen, Evelina Martinenaite, Özcan Met, Inge Marie Svane, Lene Meldgaard Knudsen, Mads Hald Andersen
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
BackgroundImmune checkpoint blockade with monoclonal antibodies targeting programmed death 1 (PD-1) and its ligand PD-L1 has played a major role in the rise of cancer immune therapy. We have identified naturally occurring self-reactive T cells specif
Externí odkaz:
https://doaj.org/article/7f7ed53b337b4e298785329ef55f4ebd
Autor:
Morten Orebo, Holmström, Uffe, Klausen, Nicolai Grønne, Jørgensen, Staffan, Holmberg, Jacob, Grauslund, Özcan, Met, Inde Marie, Svane, Lars Møller, Pedersen, Lene Meldgaard, Knudsen, Hans Carl, Hasselbalch, Mads Hald, Andersen
Publikováno v:
Ugeskrift for laeger. 181(10)
Cancer immune therapy is now used routinely for the treatment of several solid malignancies, albeit just recently having entered the clinic for treatment of haematological malignancies. Several studies demonstrate that cancer immune therapy is a prom
Autor:
Maja Bech Juul, Pernille Hammershoej Jensen, Lars Munksgaard, Michael Roost Clausen, Lene Meldgaard Knudsen, Thomas Stauffer Larsen, Henrik Frederiksen, Tarec Christoffer El-Galaly, Joachim Baech, Helene Bjoerg Kristensen, Donika Haziri, Rebecca Valentin, Lene Schurmann, Sonja Wehberg, Andriette Dessau-Arp, Henriette Engberg
Publikováno v:
Juul, M B, Jensen, P H, Engberg, H, Wehberg, S, Dessau-Arp, A, Haziri, D, Kristensen, H B, Baech, J, Schurmann, L, Clausen, M R, Valentin, R, Knudsen, L M, Munksgaard, L, El-Galaly, T C, Frederiksen, H & Larsen, T S 2018, ' Treatment strategies and outcomes in diffuse large B-cell lymphoma among 1011 patients aged 75 years or older : A Danish population-based cohort study ', European Journal of Cancer, vol. 99, pp. 86-96 . https://doi.org/10.1016/j.ejca.2018.05.006
BACKGROUND: Optimal treatment strategy for the oldest patients with diffuse large B-cell lymphoma (DLBCL) remains controversial, as this group often is precluded from clinical trials, and population-based studies are limited.METHODS: All Danish DLBCL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78d3703f738aa55dd6da4b67b9076b33
https://pure.au.dk/portal/da/publications/treatment-strategies-and-outcomes-in-diffuse-large-bcell-lymphoma-among-1011-patients-aged-75-years-or-older(0ce58589-61ae-4448-974d-07103d539027).html
https://pure.au.dk/portal/da/publications/treatment-strategies-and-outcomes-in-diffuse-large-bcell-lymphoma-among-1011-patients-aged-75-years-or-older(0ce58589-61ae-4448-974d-07103d539027).html
Autor:
Eva Kannik Hastrup, Simon Husby, Anne Fischer-Nielsen, Erik Segel, Michael Thorsgaard, Christian Nielsen, Bente Arboe, Kathrine Grell, Jakob Werner Hansen, Tarec Christoffer El-Galaly, Lene Hyldahl Ebbesen, Kirsten Grønbæk, German G. R. Gonzalez, Lisbeth Pernille Andersen, Lene Meldgaard Knudsen, Joachim Weisenfeldt, Favero Francesco, Ilse Christiansen, Per Boye Hansen, Erik Clasen-Linde, John Bæch, Thomas Stauffer Larsen, Betina Samuelsen Sørensen, Susanne G. Saekmose, Peter de Nully Brown, Pär Josefsson
Publikováno v:
Husby, S, Favero, F, Nielsen, C, Sørensen, B, Bæch, J, Hansen, J W, Gonzalez, G G R, Arboe, B, Andersen, L P, Hastrup, E K, Fischer-Nielsen, A, Saekmose, S G, Hansen, P B, Christiansen, I, Clasen-Linde, E, Knudsen, L M, Grell, K, Segel, E K, Ebbesen, L H, Thorsgaard, M, Josefsson, P L, El-Galaly, T, de Nully Brown, P, Weisenfeldt, J, Larsen, T S & Grønbæk, K 2018, ' Clinical Impact of Clonal Hematopoiesis after Autologous Stem Cell Transplantation for Lymphoma : A National Population-Based Cohort Study ', 60th ASH Annual Meeting & Exposition, San Diego, United States, 01/12/2018-04/12/2018 . < http://ash.confex.com/ash/2018/webprogram/Paper109893.html >
Husby, S, Francesco, F, Nielsen, C, Sorensen, B, Baech, J, Hansen, J W, Gonzalez, G G R, Arboe, B, Andersen, L P, Hastrup, E K, Fischer-Nielsen, A, Saekmose, S G, Hansen, P B, Christiansen, I, Clasen-Linde, E, Knudsen, L M, Grell, K, Segel, E K, Ebbesen, L H, Thorsgaard, M, Josefsson, P L, El-Galaly, T C, Brown, P D N, Weisenfeldt, J, Larsen, T S & Gronbaek, K 2018, ' Clinical Impact of Clonal Hematopoiesis after Autologous Stem Cell Transplantation for Lymphoma: A National Population-Based Cohort Study ', Blood, bind 132, nr. Suppl. 1 . https://doi.org/10.1182/blood-2018-99-109893
Husby, S, Francesco, F, Nielsen, C, Sorensen, B, Baech, J, Hansen, J W, Gonzalez, G G R, Arboe, B, Andersen, L P, Hastrup, E K, Fischer-Nielsen, A, Saekmose, S G, Hansen, P B, Christiansen, I, Clasen-Linde, E, Knudsen, L M, Grell, K, Segel, E K, Ebbesen, L H, Thorsgaard, M, Josefsson, P L, El-Galaly, T C, Brown, P D N, Weisenfeldt, J, Larsen, T S & Gronbaek, K 2018, ' Clinical Impact of Clonal Hematopoiesis after Autologous Stem Cell Transplantation for Lymphoma: A National Population-Based Cohort Study ', Blood, bind 132, nr. Suppl. 1 . https://doi.org/10.1182/blood-2018-99-109893
Background: Somatic driver mutations in hematopoietic cells may lead to clonal hematopoiesis of indeterminate potential (CHIP). In patients with lymphoma CHIP has been associated with increased risk of therapy-related myeloid neoplasms (tMN) and infe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f495ab64e4a567d014790b7c70527275
https://vbn.aau.dk/da/publications/f05c7670-0dd1-47d0-892a-6346ca86c77e
https://vbn.aau.dk/da/publications/f05c7670-0dd1-47d0-892a-6346ca86c77e
Autor:
Lene Hyldahl Ebbesen, Joachim Weischenfeldt, T.C. El-Galaly, Francesco Favero, Christian Nielsen, Pernille Andersen, Peter de Nully Brown, Anne Fischer-Nielsen, Simon Husby, Pär Josefsson, Per Boye Hansen, Michael Thorsgaard, Erik Segel, Kirsten Grønbæk, Eva Haastrup, Lene Meldgaard Knudsen, Bente Arboe, F.G. Rodriguez‐Gonzalez, Susanne G. Saekmose, Betina Samuelsen Sørensen, Erik Clasen-Linde, John Bæch, Thomas Stauffer Larsen, Kathrine Grell, Ilse Christiansen, Jakob Werner Hansen
Publikováno v:
Husby, S, Favero, F, Nielsen, C, Sørensen, B, Bæch, J, Hansen, J W, Rodriguez-Gonzalez, F G, Arboe, B, Andersen, P L, Haastrup, E K, Fischer-Nielsen, A, Sækmose, S G, Hansen, P B, Christiansen, I, Clasen-Linde, E, Knudsen, L M, Grell, K, Segel, E K, Ebbesen, L H, Thorsgaard, M, Josefsson, P L, El-Galaly, T C, Brown, P D, Weischenfeldt, J, Larsen, T S & Grønbæk, K 2019, ' High risk of adverse events after autologous stem-cell transplantation in lymphoma patients with dna repair pathway mutations : a nation-wide cohort study ', Hematological Oncology, vol. 37, no. S2, pp. 190-191 . https://doi.org/10.1002/hon.5_2630
Autor:
Max Rohde, Janne Buck Christensen, Christian Godballe, Paw Christian Holdgaard, Poul Flemming Høilund-Carlsen, Jens Karstoft, Jørgen Johansen, Dorte Gad, Poul Henning Madsen, Lene Meldgaard Knudsen, Dorte Teilmann-Jørgensen, Ole Mogensen, Karsten Bech, Anders Eggert Gravergaard, Henrik Petersen, Bodil Elisabeth Engelmann, Allan Johansen
Publikováno v:
Petersen, H, Holdgaard, P C, Madsen, P H, Meldgaard Knudsen, L, Gad, D, Gravergaard, A E, Rohde, M, Godballe, C, Engelmann, B E, Bech, K, Teilmann-Jørgensen, D, Mogensen, O, Karstoft, J, Johansen, J, Buck Christensen, J, Johansen, A, Høilund-Carlsen, P F & PET/CT Task Force of the Region of Southern Denmark 2016, ' FDG PET/CT in cancer : comparison of actual use with literature-based recommendations ', European Journal of Nuclear Medicine and Molecular Imaging, vol. 43, no. 4, pp. 695–706 . https://doi.org/10.1007/s00259-015-3217-0
European Journal of Nuclear Medicine and Molecular Imaging
European Journal of Nuclear Medicine and Molecular Imaging
Purpose The Region of Southern Denmark (RSD), covering 1.2 of Denmark’s 5.6 million inhabitants, established a task force to (1) retrieve literature evidence for the clinical use of positron emission tomography (PET)/CT and provide consequent recom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::544e5f417e5ba2e37eb14d4f5a3e280a
https://portal.findresearcher.sdu.dk/da/publications/56411379-576d-4fa8-b342-cfa4f64544c2
https://portal.findresearcher.sdu.dk/da/publications/56411379-576d-4fa8-b342-cfa4f64544c2
Autor:
Marie Klinge Brimnes, Peter Gimsing, Lene Meldgaard Knudsen, Inge Marie Svane, Hans Erik Johnsen, Annette Juul Vangsted, Anne Ortved Gang
Publikováno v:
Scandinavian Journal of Immunology. 72:540-547
Patients with multiple myeloma (MM) suffer from a general impaired immunity comprising deficiencies in humoral responses, T-cell responses as well as dendritic cell (DC) function. Thus, to achieve control of tumour growth through immune therapy const
Autor:
Thomas Rasmussen, Michael Kuehl, Inger Marie S. Dahl, Gitte Kerndrup, Hans Erik Johnsen, Lene Meldgaard Knudsen, Jacob Haaber, Marianne Lodahl
Publikováno v:
Rasmussen, T, Christensen, J H, Bahn, I M D, Meldgaard Knudsen, L, Kerndrup, G B, Lodahl, M, Johnsen, H E & Kuehl, M 2010, ' Identification of translocation products but not K-RAS mutations in memory B cells from patients with multiple myeloma ', Haematologica, vol. 95, no. 10, pp. 1730-7 . https://doi.org/10.3324/haematol.2010.024778
Rasmussen, T, Haaber, J, Dahl, I M, Knudsen, L M, Kerndrup, G B, Lodahl, M, Johnsen, H E & Kuehl, M 2010, ' Identification of translocation products but not K-RAS mutations in memory B cells from patients with multiple myeloma ', Haematologica, vol. 95, no. 10, pp. 1730-7 . https://doi.org/10.3324/haematol.2010.024778
Rasmussen, T, Haaber, J, Dahl, I M, Knudsen, L M, Kerndrup, G B, Lodahl, M, Johnsen, H E & Kuehl, M 2010, ' Identification of translocation products but not K-RAS mutations in memory B cells from patients with multiple myeloma ', Haematologica, vol. 95, no. 10, pp. 1730-7 . https://doi.org/10.3324/haematol.2010.024778
Udgivelsesdato: 2010-Oct BACKGROUND: Several laboratories have shown that cells with a memory B-cell phenotype can have the same clonotype as multiple myeloma tumor cells. DESIGN AND METHODS: The aim of this study was to determine whether some memory
Publikováno v:
European Journal of Haematology. 53:207-212
This study describes the occurrence of renal failure among 1353 newly diagnosed cases of multiple myeloma. Renal function was evaluated by serum creatinine concentration in 1353 cases, 31% of whom had renal failure at the time of diagnosis. In 1206 c
Autor:
Inger Marie S. Dahl, Marianne Lodahl, Thomas Rasmussen, Lene Meldgaard Knudsen, Peter Gimsing, Tina Damgaard
Publikováno v:
Damgaard, T, Knudsen, L M, Dahl, I M S, Gimsing, P, Lodahl, M & Rasmussen, T 2009, ' Regulation of the CD56 promoter and its association with proliferation, anti-apoptosis and clinical factors in multiple myeloma ', Leukemia and Lymphoma, vol. 50, no. 2, pp. 236-46 . https://doi.org/10.1080/10428190802699332
Udgivelsesdato: 2009-Feb Multiple myeloma (MM) is an incurable B-cell malignancy characterised by uncontrolled growth and accumulation of malignant plasma cells in the bone marrow. Aberrant expression of CD56 in patients with MM is thought to contrib