Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Lene Buhl Riis"'
Autor:
Jaslin Pallikkunnath James, Boye Schnack Nielsen, Ib Jarle Christensen, Ebbe Langholz, Mikkel Malham, Tim Svenstrup Poulsen, Kim Holmstrøm, Lene Buhl Riis, Estrid Høgdall
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Differential diagnosis of inflammatory bowel disease (IBD) to Crohn’s disease (CD) or ulcerative colitis (UC) is crucial for treatment decision making. With the aim of generating a clinically applicable molecular-based tool to classify IBD
Externí odkaz:
https://doaj.org/article/d978c2381668411fa9631bc9104e9339
Autor:
Jaslin P James, Lene Buhl Riis, Rolf Søkilde, Mikkel Malham, Estrid Høgdall, Ebbe Langholz, Boye Schnack Nielsen
Publikováno v:
PLoS ONE, Vol 19, Iss 2, p e0297353 (2024)
Numerous pathogenic processes are mediated by short noncoding RNAs (sncRNA). Twenty percent of inflammatory bowel disease (IBD) patients are labelled as IBD unclassified (IBDU) at disease onset. Most IBDU patients are reclassified as Crohn's disease
Externí odkaz:
https://doaj.org/article/27ca41d1db3243afacb9008a0e69d617
Autor:
Ole Haagen Nielsen, Søren Jacobsen, Inge Marie Svane, Julia Sidenius Johansen, Dorte Lisbet Nielsen, Peter Vilmann, Lene Buhl Riis, Rikke Boedker Holmstroem, Susann Theile, Jacob Tveiten Bjerrum, Mogens Karsbøl Boisen, Rikke Helene Løvendahl Eefsen, Inna Markovna Chen
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 9 (2022)
Background Immune-related adverse events due to immune checkpoint inhibitors (ICIs) are not always effectively treated using glucocorticoids and it may negatively affect the antitumor efficacy of ICIs. Interventional studies of alternatives to glucoc
Externí odkaz:
https://doaj.org/article/da6a783c8a484ee48ff0fad18bb11269
Autor:
Jakob Benedict Seidelin, Martin Iain Bahl, Tine Rask Licht, Benjamin E. Mead, Jeffrey M. Karp, Jens Vilstrup Johansen, Lene Buhl Riis, Marina Ramírez Galera, Anders Woetmann, Jacob Tveiten Bjerrum
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 4, Pp 1281-1296 (2021)
Background and aims: The trigger hypothesis opens the possibility of anti-flare initiation therapies by stating that ulcerative colitis (UC) flares originate from inadequate responses to acute mucosal injuries. However, experimental evidence is restr
Externí odkaz:
https://doaj.org/article/4c66f520e857498a82ad966486d1bdad
Autor:
Marco Donia, Troels Holz Borch, Özcan Met, Julie Westerlin Kjeldsen, Morten Nielsen, Inge Marie Svane, Anders Handrup Kverneland, Christopher Aled Chamberlain, Sofie Kirial Mørk, Cathrine Lund Lorentzen, Lise Pyndt Jørgensen, Lene Buhl Riis, Christina Westmose Yde
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 10 (2021)
Externí odkaz:
https://doaj.org/article/f0af08021a4a4bf1a713d50b686b096c
Publikováno v:
Translational Oncology, Vol 14, Iss 1, Pp 100892- (2021)
Cancer metastases accounts for most cancer deaths. The secreting glycoprotein Wnt5a impairs tumor cell migration and reduces invasiveness and metastasis. High Wnt5a expression in tumor cells is correlated to better outcomes in patients with breast, p
Externí odkaz:
https://doaj.org/article/142b694bfd4047ac8e36cd06ff375cce
Autor:
Christian Børde Arkteg, Sveinung Wergeland Sørbye, Lene Buhl Riis, Stig Manfred Dalen, Jon Florholmen, Rasmus Goll
Publikováno v:
PLoS ONE, Vol 16, Iss 3, p e0248224 (2021)
BackgroundHistological evaluation of ulcerative colitis (UC) patients has been debated ever since the first description of the disease and its role in follow-up has never been fully established. Recent evidence suggests an added benefit in accuracy w
Externí odkaz:
https://doaj.org/article/635b28cbe9664210befe3d58eea59dc9
Autor:
Yuan Li, Christoffer Soendergaard, Fredrik Holmberg Bergenheim, David M. Aronoff, Ginger Milne, Lene Buhl Riis, Jakob Benedict Seidelin, Kim B. Jensen, Ole Haagen Nielsen
Publikováno v:
EBioMedicine, Vol 36, Iss , Pp 497-507 (2018)
Background: Inhibition of tumor necrosis factor-α (TNF) signaling is beneficial in the management of ulcerative colitis (UC), but up to one-third of patients do not have a clinical response of relevance to TNF inhibitors during induction therapy (i.
Externí odkaz:
https://doaj.org/article/0719026df3bf4c609818e01bac61ab68
Autor:
Pia Klausen, John Gásdal Karstensen, Mehmet Coskun, Adrian Săftoiu, Peter Vilmann, Jack Bernard Cowland, Lene Buhl Riis
Publikováno v:
Gastroenterology Research and Practice, Vol 2018 (2018)
Background. Small mothers against decapentaplegic (SMAD)4 and SMAD7 are key regulatory components in the immunosuppressive transforming growth factor- (TGF-) β signaling pathway, which is defective in inflammatory bowel disease (IBD). SMAD4 may play
Externí odkaz:
https://doaj.org/article/aee83195736b4eb9b457c7d29e99e001
Autor:
Jacob Tveiten Bjerrum, Yulan Wang, Jingtao Zhang, Lene Buhl Riis, Ole Haagen Nielsen, Jakob Benedict Seidelin
Publikováno v:
Bjerrum, J T, Wang, Y, Zhang, J, Riis, L B, Nielsen, O H & Seidelin, J B 2022, ' Lipidomic Trajectories Characterize Delayed Mucosal Wound Healing in Quiescent Ulcerative Colitis and Identify Potential Novel Therapeutic Targets ', International Journal of Biological Sciences, vol. 18, no. 5, pp. 1813-1828 . https://doi.org/10.7150/ijbs.67112
Improving the long-term prognosis of ulcerative colitis (UC) requires sustained deep mucosal colonic healing with histologic remission, making the study of colonic tissue regeneration essential. In experimental colitis models, lipid metabolites are r