Development, Manufacturing and Characterization of a Highly Purified, Liquid Immunoglobulin G Preparation from Human Plasma

Autor: Flemming Balstrup, John S. Sullivan, Inga Laursen, Peter Bang, Gunnar Houen, Lene Blou

Publikováno v: Transfusion Medicine and Hemotherapy. 41:205-212

Background: The use of plasma-derived immunoglobulin G (IgG) is increasing, and the number of diseases, including immunodeficiencies, neurological diseases and autoimmune conditions, treated with intravenous IgG (IVIG) is expanding. Consequently, the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e79c5f41741d813b47f9a5f1df80c75
https://doi.org/10.1159/000357982

Large-scale purification and characterization of non-glycosylated Gc globulin (vitamin D-binding protein) from plasma fraction IV

Autor: Gunnar Houen, Lene Blou, Charlotte Sværke Jørgensen, Peter Højrup, Inga Laursen, Maja Christiansen, Lisbeth B. Krogsøe

Publikováno v: Biotechnology and applied biochemistry. 44(Pt 1)

Gc globulin, also called vitamin D-binding protein, is a plasma protein involved in the extracellular actin-scavenger system. Low levels of Gc globulin have been found to correlate with multiple organ failure and nonsurvival of patients with fulminan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3cc1d809434c12a911eb1eb8ae25cae
https://pubmed.ncbi.nlm.nih.gov/16402919

Human plasma-derived mannose-binding lectin: a phase I safety and pharmacokinetic study

Autor: Lene Blou, T. Vikingsdottir, Helgi Valdimarsson, Saedis Saevarsdottir, Michael Christiansen, Claus Koch, O. Oskarsson, Inga Laursen, Johann E. Gudjonsson, Peter Bang

Publikováno v: Valdimarsson, H, Vikingsdottir, T, Bang, P, Saevarsdottir, S, Gudjonsson, J E, Oskarsson, O, Christensen, M, Blou, L, Laursen, I & Koch, C 2004, ' Human plasma-derived mannose-binding lectin: a phase I safety and pharmacokinetic study. ', Scandinavian Journal of Immunology, vol. 59, pp. 97-102 .

Mannose-binding lectin (MBL) is an important component of innate immunity that can bind to certain sugar residues on the surface of many types of pathogenic micro-organisms. On binding, MBL generates opsonic activity mainly through activation of the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32b4145db99fabe50a3ce37b7a064ae0
https://pubmed.ncbi.nlm.nih.gov/14723627

Large-scale purification and characterization of non-glycosylated Gc globulin (vitamin D-binding protein) from plasma fraction IV.

Autor: Charlotte S. Jørgensen, Maja Christiansen, Inga Laursen, Lisbeth B. Krogsøe, Peter Højrup, Lene Blou, Gunnar Houen

Publikováno v: Biotechnology & Applied Biochemistry; 2006, Vol. 044 Issue 1, p35-44, 10p