Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Lene Øygarden"'
Autor:
Kit M. Kovacs, Anders Goksøyr, Lene Øygarden, Heli Routti, Roger Lille-Langøy, Katharina Lühmann, Christian Lydersen
Publikováno v:
Environmental sciencetechnology. 54(9)
This study reports the transcriptional activity of fin (Balaenoptera physalus) and blue whale (Balaenoptera musculus) peroxisome proliferator-activated receptor γ (PPARG), glucocorticoid receptor (GR), and thyroid hormone receptor β (THRB), when ex
Autor:
Rune Dietz, Lene Øygarden, Mikael Harju, Anders Goksøyr, Roger Lille-Langøy, Mari Katrine Berg, Heli Routti, Christian Sonne
Publikováno v:
Scientific Reports
Routti, H, K. Berg, M, Lille-Langøy, R, Øygarden, L, Harju, M, Dietz, R, Sonne, C & Goksøyr, A 2019, ' Environmental contaminants modulate the transcriptional activity of polar bear (Ursus maritimus) and human peroxisome proliferator-activated receptor alpha (PPARA) ', Scientific Reports, vol. 9, no. 1, 6918 . https://doi.org/10.1038/s41598-019-43337-w
Scientific Reports, Vol 9, Iss 1, Pp 1-14 (2019)
Routti, H, K. Berg, M, Lille-Langøy, R, Øygarden, L, Harju, M, Dietz, R, Sonne, C & Goksøyr, A 2019, ' Environmental contaminants modulate the transcriptional activity of polar bear (Ursus maritimus) and human peroxisome proliferator-activated receptor alpha (PPARA) ', Scientific Reports, vol. 9, no. 1, 6918 . https://doi.org/10.1038/s41598-019-43337-w
Scientific Reports, Vol 9, Iss 1, Pp 1-14 (2019)
Peroxisome proliferator-activated receptor alfa (PPARA/NR1C1) is a ligand activated nuclear receptor that is a key regulator of lipid metabolism in tissues with high fatty acid catabolism such as the liver. Here, we cloned PPARA from polar bear liver
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da9439be0899b84d3637bebfdfec0f11
http://hdl.handle.net/11250/2606603
http://hdl.handle.net/11250/2606603
Autor:
Ingebrigt Sylte, Roger Lille-Langøy, Marte Rusten, Mari Katrine Berg, Lene Øygarden, Pawel Rostkowski, Mikael Harju, Kurt Kristiansen, Trine Fink, Heli Routti, Anders Goksøyr
Publikováno v:
Routti, H, Lille-Langøy, R, Berg, M K, Fink, T, Harju, M, Kristiansen, K, Rostkowski, P, Rusten, M, Sylte, I, Øygarden, L & Goksøyr, A 2016, ' Environmental chemicals modulate polar bear (Ursus maritimus) peroxisome proliferator-activated receptor gamma (PPARG) and adipogenesis in vitro ', Environmental Science & Technology, vol. 50, no. 19, pp. 10708-10720 . https://doi.org/10.1021/acs.est.6b03020
We studied interactions between polar bear peroxisome proliferator-activated receptor gamma (pbPPARG) and selected compounds using a luciferase reporter assay and predictions through molecular docking. Furthermore, we studied adipogenesis by liver an