Generation, characterization and genetic engineering of myogenic cells to restore dystrophin expression in a mouse model of Duchenne muscular dystrophy

Autor: Lenardič, Ajda

Duchenne muscular dystrophy is the most severe form of muscular dystrophy. It is caused by frameshift mutations in dystrophin gene, which lead to the production of truncated, non-functional dystrophin protein. Treatment options for Duchenne muscular

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3505::fbd631dbcc43fc91a194297e109fadc3
https://hdl.handle.net/20.500.12556/RUL-135055

Iron Syrup Corrects Iron Status in a Mouse Model of Diet-Induced Iron Deficiency

Autor: Pirman, Tatjana, Lenardič, Ajda, Svete, Alenka Nemec, Horvat, Simon

Publikováno v: Biology
Volume 10
Issue 5

The objective of this study was to compare the effects of >
Your<
Iron Syrup, a novel oral liquid iron-containing food supplement, with the commonly prescribed iron sulphate (Fe-sulphate) in a mouse model of diet-induced iron deficiency

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=multidiscipl::7b6f51d3e550d15586eaeedb992fc2e9

Aktivacija izražanja gena Tst z metodo CRISPR/dCas9-VPR v mišji celični liniji

Autor: Lenardič, Ajda

Debelost in z njo povezana sladkorna bolezen tipa 2 (SBT2)sta med najbolj razširjenimi boleznimi sodobnega časa. Na svetu je 13% odraslih debelih in 39 % prekomerno težkih, za SBT2pa trpi okrog 8 % svetovne populacije. Zaenkrat še ne poznamo uči

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3505::7344734f0b03ea714fa82d78a06ae482
https://repozitorij.uni-lj.si/Dokument.php?id=125539&dn=

CRISPR/Cas9 editing of directly reprogrammed myogenic progenitors restores dystrophin expression in a mouse model of muscular dystrophy.

Autor: Domenig SA; Laboratory of Regenerative and Movement Biology, Institute of Human Movement Sciences and Sport, Department of Health Sciences and Technology, Swiss Federal Institute of Technology (ETH) Zurich, Schwerzenbach, Switzerland., Bundschuh N; Laboratory of Regenerative and Movement Biology, Institute of Human Movement Sciences and Sport, Department of Health Sciences and Technology, Swiss Federal Institute of Technology (ETH) Zurich, Schwerzenbach, Switzerland., Lenardič A; Laboratory of Regenerative and Movement Biology, Institute of Human Movement Sciences and Sport, Department of Health Sciences and Technology, Swiss Federal Institute of Technology (ETH) Zurich, Schwerzenbach, Switzerland., Ghosh A; Laboratory of Regenerative and Movement Biology, Institute of Human Movement Sciences and Sport, Department of Health Sciences and Technology, Swiss Federal Institute of Technology (ETH) Zurich, Schwerzenbach, Switzerland; Functional Genomics Center Zurich, Swiss Federal Institute of Technology (ETH) Zurich and University of Zurich, Zurich, Switzerland., Kim I; Laboratory of Regenerative and Movement Biology, Institute of Human Movement Sciences and Sport, Department of Health Sciences and Technology, Swiss Federal Institute of Technology (ETH) Zurich, Schwerzenbach, Switzerland., Qabrati X; Laboratory of Regenerative and Movement Biology, Institute of Human Movement Sciences and Sport, Department of Health Sciences and Technology, Swiss Federal Institute of Technology (ETH) Zurich, Schwerzenbach, Switzerland., D'Hulst G; Laboratory of Regenerative and Movement Biology, Institute of Human Movement Sciences and Sport, Department of Health Sciences and Technology, Swiss Federal Institute of Technology (ETH) Zurich, Schwerzenbach, Switzerland., Bar-Nur O; Laboratory of Regenerative and Movement Biology, Institute of Human Movement Sciences and Sport, Department of Health Sciences and Technology, Swiss Federal Institute of Technology (ETH) Zurich, Schwerzenbach, Switzerland. Electronic address: Ori.bar-nur@hest.ethz.ch.

Publikováno v: Stem cell reports [Stem Cell Reports] 2022 Feb 08; Vol. 17 (2), pp. 321-336. Date of Electronic Publication: 2022 Jan 06.