Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Lena-Sophie Dreher"'
Autor:
Lena-Sophie Dreher, Thorsten Hoppe
Upregulation of Endoplasmic Reticulum‐Associated Degradation (ERAD) in the liver upon feeding and organismal growth aggravates proteasomal turnover of the transcription factor CREBH and decreases the expression of its target gene, the hepatokine FG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3b6bdab29be60beaa58ca770847d145
https://europepmc.org/articles/PMC6236333/
https://europepmc.org/articles/PMC6236333/
Autor:
John C. Christianson, Lena-Sophie Dreher, Jasmin Schulz, Emma J. Fenech, Dönem Avci, Thorsten Hoppe, Yuki Hayashi, Norbert Volkmar, Markus A. Queisser, Aljona Gutschmidt
The mammalian ubiquitin ligase Hrd1 is the central component of a complex facilitating degradation of misfolded proteins during the ubiquitin–proteasome-dependent process of ER-associated degradation (ERAD). Hrd1 associates with cofactors to execut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8cea0ffb7b2f0c330ba2e82f080440a
https://doi.org/10.1242/jcs.206847
https://doi.org/10.1242/jcs.206847
Autor:
Lena-Sophie Dreher, Thorsten Hoppe
Publikováno v:
Molecular Cell. 71:481-482
Endoplasmic reticulum-associated degradation (ERAD) plays a crucial role in turnover of defective secretory proteins to maintain protein homeostasis. Cha et al. (2018) revealed that the anti-diabetic drug metformin induces ERAD of programmed death li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1cb35822cb3ceefdf77ed533da43730b
https://doi.org/10.1016/j.molcel.2018.08.001
https://doi.org/10.1016/j.molcel.2018.08.001
