Výsledky vyhledávání

Growth hormone (GH) replacement therapy in GH-deficient women during pregnancy

Autor: Cesar Luiz Boguszewski, Gudmundur Johannsson, Lena Wirén

Publikováno v: Clinical Endocrinology. 57:235-239

Summary objective The present recommendation is to discontinue GH replacement therapy in hypopituitary women, as they become pregnant. We report our experience of managing GH deficiency with GH replacement therapy in pregnant hypopituitary women. pat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::af0e019f4a7439fc3902018a4de1836c
https://doi.org/10.1046/j.1365-2265.2002.01572.x

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Currently used growth-promoting treatment of children results in normal bone mass and density. A prospective trial of discontinuing growth hormone treatment in adolescents‡

Autor: Hans Fors, Ingvar Bosaeus, Bengt-Åke Bengtsson, Gudmundur Johannsson, Lena Wirén, Ragnar Bjarnason, Kerstin Albertsson-Wikland

Publikováno v: Clinical Endocrinology. 55:617-624

BACKGROUND AND AIMS The need for continued GH replacement in patients with childhood-onset GH deficiency (GHD) into adulthood has been recognized. The consequences of discontinuing GH treatment on bone mineralization in adolescent patients with GHD a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::77d9fa70de167191ab6e9a66e2dff265
https://doi.org/10.1046/j.1365-2265.2001.01386.x

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A Prospective Investigation of Quality of Life and Psychological Well-Being after the Discontinuation of GH Treatment in Adolescent Patients Who Had GH Deficiency during Childhood

Autor: Bengt-Åke Bengtsson, Lena Wirén, Gudmundur Johannsson

Publikováno v: The Journal of Clinical Endocrinology & Metabolism. 86:3494-3498

Some patients given growth-promoting therapy for GH deficiency in childhood will remain GH deficient in their adult lives and hence could benefit from continued GH replacement therapy. This longitudinal study sought to assess whether quality of life

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f139ff66e88d71014003c8c959a9d4e1
https://doi.org/10.1210/jcem.86.8.7709

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Application of a disease-specific, quality-of-life measure (QoL-AGHDA) in growth hormone-deficient adults and a random population sample in Sweden: validation of the measure by Rasch analysis

Autor: Lars Wilhelmsen, Lena Wirén, Whalley D, Stephen P. McKenna

Publikováno v: Clinical Endocrinology. 52:143-152

OBJECTIVE Growth hormone deficiency (GHD) in adults has been associated with impaired health status and quality of life (QoL) in several studies using generic measures, and in a few studies using recently developed disease-specific measures. Theoreti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3e66c6275127452c112b7b4b288e0289
https://doi.org/10.1046/j.1365-2265.2000.00899.x

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[Untitled]

Autor: Mauro Niero, Luis Prieto, Stephen P. McKenna, Jordi Alonso, Lena Wirén, Thomas Kohlmann, Lynda C. Doward

Publikováno v: Quality of Life Research. 8:373-383

Several studies have shown that growth hormone deficiency in adults leads to poor well-being and other clinical consequences, and that these improve when the hormone is replaced. However, the studies employed generic measures of health status that mi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::338ba3b041d46f790b6120948cee719e
https://doi.org/10.1023/a:1008987922774

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Beneficial effects of long-term GH replacement therapy on quality of life in adults with GH deficiency

Autor: Lena Wirén, Gudmundur Johannsson, Bengt-Åke Bengtsson

Publikováno v: Clinical Endocrinology. 48:613-620

OBJECTIVE Quality of life tends to be adversely affected in adults with GH deficiency. The aim of this study was to examine changes in quality of life in a large group of GH-deficient adults receiving long-term GH replacement therapy. DESIGN The stud

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::57feecf9b568bd840abc1e9f229d4897
https://doi.org/10.1046/j.1365-2265.1998.00462.x

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Compromised quality of life in adult patients who have received a radiation dose towards the basal part of the brain. A case-control study in long-term survivors from cancer in the head and neck region

Autor: Claes Mercke, Helge Malmgren, Gudmundur Johannsson, Karl-Axel Johansson, Erik Olsson, Maria Leonsson Zachrisson, Lena Wirén, Elisabet Löfdahl, Gertrud Berg

Publikováno v: Radiation Oncology (London, England)
Radiation Oncology, Vol 7, Iss 1, p 179 (2012)

Background Adult patients with hypothalamic-pituitary disorders have compromised quality of life (QoL). Whether this is due to their endocrine consequences (hypopituitarism), their underlying hypothalamic-pituitary disorder or both is still under deb

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::922870d52ff41d066955093eb1aee2c4
https://pubmed.ncbi.nlm.nih.gov/23101561

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A new self-assessment questionnaire to measure well-being in children, particularly those of short stature

Autor: Lena Wirén, Johan Karlberg, A. Erling, Kerstin Albertsson-Wikland, Ingela Wiklund

Publikováno v: Quality of Life Research. 3:449-455

The impact of short stature on children is commonly assessed in terms of psychosocial consequences. Proxy respondents and formal behavioural performance tests constitute standard methods in the evaluation of growth hormone therapy in children of shor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2051fb392335e8626a36ec124a22c495
https://doi.org/10.1007/bf00435397

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