Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Lena Wiedmann"'
Autor:
Lena Wiedmann, Francesca De Angelis Rigotti, Nuria Vaquero-Siguero, Elisa Donato, Elisa Espinet, Iris Moll, Elisenda Alsina-Sanchis, Hanibal Bohnenberger, Elena Fernandez-Florido, Ronja Mülfarth, Margherita Vacca, Jennifer Gerwing, Lena-Christin Conradi, Philipp Ströbel, Andreas Trumpp, Carolin Mogler, Andreas Fischer, Juan Rodriguez-Vita
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Pancreatic ductal adenocarcinoma (PDAC) frequently metastasizes into the peritoneum, which contributes to poor prognosis. Metastatic spreading is promoted by cancer cell plasticity, yet its regulation by the microenvironment is incompletely
Externí odkaz:
https://doaj.org/article/2e93fce2b3b54b13883ba9d597b21173
Autor:
Gretchen Wolff, Minako Sakurai, Amit Mhamane, Maria Troullinaki, Adriano Maida, Ioannis K. Deligiannis, Kelvin Yin, Peter Weber, Jakob Morgenstern, Annika Wieder, Yun Kwon, Revathi Sekar, Anja Zeigerer, Michael Roden, Matthias Blüher, Nadine Volk, Tanja Poth, Thilo Hackert, Lena Wiedmann, Francesca De Angelis Rigotti, Juan Rodriguez-Vita, Andreas Fischer, Rajesh Mukthavaram, Pattraranee Limphong, Kiyoshi Tachikawa, Priya Karmali, Joseph Payne, Padmanabh Chivukula, Bilgen Ekim-Üstünel, Celia P. Martinez-Jimenez, Julia Szendrödi, Peter Nawroth, Stephan Herzig
Publikováno v:
Molecular Metabolism, Vol 60, Iss , Pp 101487- (2022)
Objective: Fibrotic organ responses have recently been identified as long-term complications in diabetes. Indeed, insulin resistance and aberrant hepatic lipid accumulation represent driving features of progressive non-alcoholic fatty liver disease (
Externí odkaz:
https://doaj.org/article/7ffd9988b903457a8a6a90287967ed13
Autor:
Maren Pein, Jacob Insua-Rodríguez, Tsunaki Hongu, Angela Riedel, Jasmin Meier, Lena Wiedmann, Kristin Decker, Marieke A. G. Essers, Hans-Peter Sinn, Saskia Spaich, Marc Sütterlin, Andreas Schneeweiss, Andreas Trumpp, Thordur Oskarsson
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
How cancer cells engage the microenvironment to establish metastasis is poorly understood. Here, the authors show that CXCR3-expressing breast cancer cells secrete IL-1 to induce a paracrine crosstalk with fibroblasts in the lung, which involves CXCL
Externí odkaz:
https://doaj.org/article/17acb7c31f7941f0959b5034c6bfd4bc
Publikováno v:
Bio-Protocol, Vol 11, Iss 3 (2021)
Vascular smooth muscle cells (VSMCs) have been cultured for decades to study the role of these cells in cardiovascular disorders. The most common source of VSMCs is the rat aorta. Here we show the adaptation of this method to isolate and culture mous
Externí odkaz:
https://doaj.org/article/6208d2c5322a41b898f5a51e851f878f
Autor:
Sana S Hasan, Markus Jabs, Jacqueline Taylor, Lena Wiedmann, Thomas Leibing, Viola Nordström, Giuseppina Federico, Leticia P Roma, Christopher Carlein, Gretchen Wolff, Bilgen Ekim‐Üstünel, Maik Brune, Iris Moll, Fabian Tetzlaff, Hermann‐Josef Gröne, Thomas Fleming, Cyrill Géraud, Stephan Herzig, Peter P Nawroth, Andreas Fischer
Publikováno v:
EMBO Molecular Medicine, Vol 12, Iss 4, Pp n/a-n/a (2020)
Abstract The role of the endothelium is not just limited to acting as an inert barrier for facilitating blood transport. Endothelial cells (ECs), through expression of a repertoire of angiocrine molecules, regulate metabolic demands in an organ‐spe
Externí odkaz:
https://doaj.org/article/1ed45c1818f945c4851ba741b9225b1a
Autor:
Juan Rodriguez-Vita, Andreas Fischer, Tilman Borggrefe, Adelheid Cerwenka, Benedetto Daniele Giaimo, Adrian Stögbauer, Francesca De Angelis Rigotti, Jacqueline Taylor, Eleni Zimmer, Tara Ziegelbauer, Lorea Jordana-Urriza, Lena Wiedmann, Sarah Böhn, Iris Moll, Ronja Mülfarth, Elisenda Alsina-Sanchis
Epithelial ovarian cancer (EOC) is one of the most lethal gynecologic cancers worldwide. EOC cells educate tumor-associated macrophages (TAM) through CD44-mediated cholesterol depletion to generate an immunosuppressive tumor microenvironment (TME). I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eee1b23eccf95afa3f52802589d35780
https://doi.org/10.1158/0008-5472.c.6514245.v1
https://doi.org/10.1158/0008-5472.c.6514245.v1
Autor:
Juan Rodriguez-Vita, Andreas Fischer, Tilman Borggrefe, Adelheid Cerwenka, Benedetto Daniele Giaimo, Adrian Stögbauer, Francesca De Angelis Rigotti, Jacqueline Taylor, Eleni Zimmer, Tara Ziegelbauer, Lorea Jordana-Urriza, Lena Wiedmann, Sarah Böhn, Iris Moll, Ronja Mülfarth, Elisenda Alsina-Sanchis
It includes extended material and methods, and supplementary figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1029341a0d2ff1ed3e5aa52aaeb1e46a
https://doi.org/10.1158/0008-5472.22432767
https://doi.org/10.1158/0008-5472.22432767
Autor:
Lena Wiedmann, Francesca De Angelis Rigotti, Nuria Vaquero-Siguero, Elisa Donato, Elisa Espinet, Iris Moll, Elisenda Alsina-Sanchis, Ronja Mülfarth, Margherita Vacca, Jennifer Gerwing, Andreas Trumpp, Andreas Fischer, Juan Rodriguez-Vita
Pancreatic ductal adenocarcinoma (PDAC) frequently metastasizes into the peritoneum, which contributes to poor prognosis. Metastatic spreading is promoted by cancer cell plasticity, yet its regulation by the microenvironment is incompletely understoo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::20b0f1635b0716df2f41998701769e62
https://doi.org/10.1101/2022.05.30.493185
https://doi.org/10.1101/2022.05.30.493185
Autor:
Elisenda Alsina-Sanchis, Ronja Mülfarth, Iris Moll, Sarah Böhn, Lena Wiedmann, Lorea Jordana-Urriza, Tara Ziegelbauer, Eleni Zimmer, Jacqueline Taylor, Francesca De Angelis Rigotti, Adrian Stögbauer, Benedetto Daniele Giaimo, Adelheid Cerwenka, Tilman Borggrefe, Andreas Fischer, Juan Rodriguez-Vita
Publikováno v:
Cancer research. 82(23)
Epithelial ovarian cancer (EOC) is one of the most lethal gynecologic cancers worldwide. EOC cells educate tumor-associated macrophages (TAM) through CD44-mediated cholesterol depletion to generate an immunosuppressive tumor microenvironment (TME). I
Autor:
Ronja Mülfarth, Elisenda Alsina-Sanchis, Iris Moll, Sarah Böhn, Lena Wiedmann, Lorea Jordana, Tara Ziegelbauer, Jacqueline Taylor, Francesca De Angelis Rigotti, Adrian Stögbauer, Benedetto Daniele Giaimo, Adelheid Cerwenka, Tilman Borggrefe, Andreas Fischer, Juan Rodriguez-Vita
Epithelial ovarian cancer (EOC) is one of the most lethal gynaecological cancers worldwide. EOC cells educate tumour-associated macrophages (TAMs) through CD44-mediated cholesterol depletion to generate an immunosuppressive tumour microenvironment (T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::769a47ac197ab36971b2b6ed817da53b
https://doi.org/10.1101/2021.12.20.473423
https://doi.org/10.1101/2021.12.20.473423