Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Lena Weiß"'
Autor:
Meinolf Karthaus, Volker Heinemann, Jorge Riera-Knorrenschild, Albrecht Kretzschmar, Manfred Welslau, Ulrich Kaiser, Henning Pelz, Thomas J. Ettrich, Swantje Held, Linde Kehmann, Jürgen Hess, Timo Reisländer, Lena Weiss, on behalf of the TALLISUR study group
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-11 (2024)
Abstract Background In the pivotal phase III RECOURSE trial, trifluridine/tipiracil (FTD/TPI) improved progression-free and overall survival (PFS, OS) of patients with pre-treated metastatic colorectal cancer (mCRC). Subsequently, the TALLISUR trial
Externí odkaz:
https://doaj.org/article/bfc837e7c22d4f35917763b74a09a350
Autor:
Maria Pouyiourou, Bianca N. Kraft, Timothy Wohlfromm, Michael Stahl, Boris Kubuschok, Harald Löffler, Ulrich T. Hacker, Gerdt Hübner, Lena Weiss, Michael Bitzer, Thomas Ernst, Philipp Schütt, Thomas Hielscher, Stefan Delorme, Martina Kirchner, Daniel Kazdal, Markus Ball, Klaus Kluck, Albrecht Stenzinger, Tilmann Bochtler, Alwin Krämer
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)
Abstract Cancer of unknown primary has a dismal prognosis, especially following failure of platinum-based chemotherapy. 10-20% of patients have a high tumor mutational burden (TMB), which predicts response to immunotherapy in many cancer types. In th
Externí odkaz:
https://doaj.org/article/cf29f4d0ded648268fe0196b4aa79152
Autor:
Laura E. Fischer, Sebastian Stintzing, Volker Heinemann, Ulrich Keilholz, Dietmar Keune, Claudia Vollbrecht, Thomas Burmeister, Andreas Kind, Lena Weiss, David Horst, Thomas Kirchner, Frederick Klauschen, Andreas Jung, Christoph Benedikt Westphalen, Ivan Jelas
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
ObjectivesThe use of liquid biopsies (LB) in patients with solid malignancies enables comprehensive genomic profiling (CGP) of circulating tumor DNA (ctDNA) and has the potential to guide therapy stratification and support disease monitoring. To exam
Externí odkaz:
https://doaj.org/article/965735d49d9549379321a45c09777ab9
Autor:
Jessica V. Redfern, Kelly A. Kryc, Lena Weiss, Brooke C. Hodge, Orfhlaith O’Brien, Scott D. Kraus, Ester Quintana-Rizzo, Peter J. Auster
Publikováno v:
Frontiers in Marine Science, Vol 8 (2021)
One of today’s greatest conservation challenges is balancing policies, laws, and management strategies established to achieve economic goals that depend on extracting ocean resources with those established to conserve marine biodiversity. We use th
Externí odkaz:
https://doaj.org/article/25ffc603d8494e6b801841c8592f73c1
Autor:
Ulrich Hegerl, Edward Watkins, Miquel Roca, Matthew Owens, Mariska Bot, Ingeborg Annemarie Brouwer, Elisabeth Kohls, Brenda Penninx, Gerard van Grootheest, Mieke Cabout, Margalida Gili, Marjolein Visser, Bep Verkerk, Nadine Paans, Carisha Thesing, Deborah Gibson-Smith, Melany Horsfall, Lena Weiss, Amy Romijn, Hannah Bunce, Owain Winfield, Harriet Bunker-Smith, Fern Durbridge, Caterina Versari Molinares, Atikah Sapar, Miquel Tortella, Clara Homar Covas, M Angeles Pérez-Ara, Adoración Castro Gracia, José Luis Reig, Jana Hoesel, Ezgi Dogan, Sabrina Baldofski, Nicole Mauche
Publikováno v:
BMJ Open, Vol 10, Iss 9 (2020)
Objectives We report on the acceptability, feasibility, dose-response relationship and adherence of two nutritional strategies to improve mood (multinutrient supplements; food-related behavioural activation (F-BA)) studied in a randomised controlled
Externí odkaz:
https://doaj.org/article/aa46b99282c0420587493e020347d60e
Publikováno v:
Biomolecular NMR Assignments. 17:121-127
The family of AT-rich interactive domain (ARID) containing proteins -Arids- contains 15 members that have almost exclusively been described as DNA-binding proteins. Interestingly, a decade ago the family member Arid5a was found to bind and stabilize
Autor:
Klara Dorman, Danmei Zhang, Kathrin Heinrich, Laurens Reeh, Lena Weiss, Michael Haas, Georg Beyer, Daniel Rössler, Elisabetta Goni, Bernhard W. Renz, Jan G. D’Haese, Wolfgang G. Kunz, Max Seidensticker, Stefanie Corradini, Maximilian Niyazi, Steffen Ormanns, Jörg Kumbrink, Andreas Jung, Frederick Klauschen, Jens Werner, Julia Mayerle, Michael von Bergwelt-Baildon, Stefan Boeck, Volker Heinemann, C. Benedikt Westphalen
Publikováno v:
Targeted Oncology. 18:257-267
Autor:
Danmei Zhang, Stephan Kruger, Karoline Schirle, Volker Heinemann, Klara Dorman, Christoph Benedikt Westphalen, Lena Weiss, Leonie Gebauer, Michael Günther, Steffen Ormanns, Jens Werner, Michael von Bergwelt-Baildon, Stefan Boeck, Michael Haas
Publikováno v:
Oncology Research and Treatment. 46:106-115
Introduction: To this date, surgery remains the only potentially curative approach in the treatment of pancreatic cancer. To analyse the clinical impact of a structured post-operative follow-up programme, we retrospectively analysed a cohort of resec
Autor:
Klara Dorman, Miriam Gerckens, Stephan Kruger, Kimberly Krueger, Zsuzsanna Mayer, Alexander Rupp, Danmei Zhang, Lena Weiss, C. Benedikt Westphalen, Michael Haas, Michael Guenther, Steffen Ormanns, Frank Klawonn, Jens Werner, Michael von Bergwelt-Baildon, Volker Heinemann, Stefan Boeck, Stefan Holdenrieder
Publikováno v:
Journal of Cancer Research and Clinical Oncology. 149:2463-2474
Purpose Novel biomarkers to better predict outcome and select the best therapeutic strategy for the individual patient are necessary for pancreatic ductal adenocarcinoma (PDAC). Methods Using a panel assay, multiple biomarkers (IFN-γ, IL-10, IL-6, I
Autor:
Qiang Li, Jutta Weitz, Chao Li, Josefine Schardey, Lena Weiss, Ulrich Wirth, Petra Zimmermann, Alexandr V. Bazhin, Jens Werner, Florian Kühn
Publikováno v:
International Journal of Colorectal Disease. 38
Background and aims Early-onset colorectal neoplasms (EoCRN) include both benign and malign colorectal tumors, which occur before the age of 50. The incidence of EoCRN is rising worldwide. Tobacco smoking has previously been proven to be related to t