Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Lena Tjeldhorn"'
Autor:
Lena Tjeldhorn, Nina Iversen, Kirsten Sandvig, Jonas Bergan, Per Morten Sandset, Grethe Skretting
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e24009 (2011)
BACKGROUND: Protein C (PC) deficiency is associated with a high risk of venous thrombosis. Recently, we identified the PC-A267T mutation in a patient with PC deficiency and revealed by in vitro studies decreased intracellular and secreted levels of t
Externí odkaz:
https://doaj.org/article/a203a448586343ae9abe61329060c98d
Autor:
Thomas Larsen Titze, Lars Henrik Dahl Hamnvik, Inga Marie Hauglum, Anne Elisabeth Tonay Carlsen, Lena Tjeldhorn, Nhan Trung Nguyen, Çiğdem Akalın Akkök
Publikováno v:
International Journal of Women's Health. 15:1-6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b5936857d2903c79ce4f30f17560380
https://doi.org/10.2147/ijwh.s390661
https://doi.org/10.2147/ijwh.s390661
Autor:
Svend Rand-Hendriksen, Benedicte Paus, Tuva Barøy, Eirik Frengen, Silja Svanstrøm Amundsen, Odd Geiran, Lena Tjeldhorn
Publikováno v:
BMC Medical Genetics
Background Pathogenic mutations in FBN1, encoding the glycoprotein, fibrillin-1, cause Marfan syndrome (MFS) and related connective tissue disorders. In the present study, qualitative and quantitative effects of 16 mutations, identified in FBN1 in MF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01d22d2ed300610bbb22605edc625790
https://doi.org/10.1186/s12881-015-0260-4
https://doi.org/10.1186/s12881-015-0260-4
Autor:
Svein Dueland, Wolfgang Lilleby, Iris Bigalke, Anne Merete Aaland Tryggestad, Grete S Andreassen, Lisbeth Skoge, Dag Josefsen, Ulrika Axcrona, Steinar Aamadal, Jens A L Jørgensen, Gjertrud Skorstad, Bjørn Brennhovd, Lena Tjeldhorn, Karol Axcrona, Lene Mowinckel, Gunnar Kvalheim, Stein Saeboe-Larsen, T Kirsti Hønnåshagen
Publikováno v:
Cancer Research. 78:CT016-CT016
Prostate cancer patients diagnosed with high Gleason score (≥ 8) and large tumors (≥T2c) are considered high-risk patients and >50% will develop an early biochemical relapse following radical surgery. Presently, there is no curative therapy avail
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::78feef0b7b43e700a7108613cd865d37
https://doi.org/10.1158/1538-7445.am2018-ct016
https://doi.org/10.1158/1538-7445.am2018-ct016
Autor:
Dag Josefsen, Wolfgang Lilleby, J.L. Jørgensen, Gunnar Kvalheim, Lena Tjeldhorn, Karol Axcrona, A.A. Tryggestad, Ulrika Axcrona, S. Sæbø-Larse, Lisbeth Skoge, Steinar Aamdal, Iris Bigalke, L. Mowinckel, Gjertrud Skorstad, Kirsti Hønnåshagen, Svein Dueland, Else Marit Inderberg, Bjørn Brennhovd, G.S. Andreassen
Publikováno v:
Cytotherapy. 19:S15
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::555e61724ad6c57d53e0585f0d5c3754
https://doi.org/10.1016/j.jcyt.2017.02.025
https://doi.org/10.1016/j.jcyt.2017.02.025
Autor:
Grethe Skretting, Nina Iversen, Kirsten Sandvig, Per Morten Sandset, Jonas Bergan, Lena Tjeldhorn
Publikováno v:
PLoS ONE
PLoS ONE, Vol 6, Iss 8, p e24009 (2011)
PLoS ONE, Vol 6, Iss 8, p e24009 (2011)
Background Protein C (PC) deficiency is associated with a high risk of venous thrombosis. Recently, we identified the PC-A267T mutation in a patient with PC deficiency and revealed by in vitro studies decreased intracellular and secreted levels of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ce3540c111adfd45d3ad154f7aa97e9
http://europepmc.org/articles/PMC3162024
http://europepmc.org/articles/PMC3162024
Autor:
Nina Iversen, Lena Tjeldhorn, Per Morten Sandset, Kirsten Sandvig, Jonas Bergan, Grethe Skretting
Publikováno v:
BMC Cell Biology
BMC Cell Biology, Vol 11, Iss 1, p 67 (2010)
BMC Cell Biology, Vol 11, Iss 1, p 67 (2010)
Background Activated protein C (PC) is a serine protease that regulates blood coagulation by inactivating coagulation factors Va and VIIIa. PC deficiency is an autosomally inherited disorder associated with a high risk of recurrent venous thrombosis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c63b4c9ae58746c0898de0469e0122f2
http://hdl.handle.net/10852/46685
http://hdl.handle.net/10852/46685
Autor:
Benedicte Paus, Svend Rand-Hendriksen, Kai Andersen, Odd Geiran, Lena Tjeldhorn, Hans-Jørgen Smith, Svein Ove Semb, Jon Offstad, Rigmor Lundby
The prevalence of each single feature in the Ghent criteria in patients with Marfan syndrome (MFS) is not known. To elucidate this, a cross-sectional study of 105 adults with presumed MFS was carried out. All patients were examined by the same group
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7b58c159fe50e96fbae38c9233e3f0e
https://europepmc.org/articles/PMC2986674/
https://europepmc.org/articles/PMC2986674/
Publikováno v:
Thrombosis research. 125(3)
Introduction Protein C (PC) is a key anticoagulant that regulates hemostasis, and inherited deficiency of PC is an established risk factor for venous thrombosis (VT). The factor V Leiden mutation causing activated PC (APC) resistance is an additional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5714841caff17b7731362ce83fbf892a
https://pubmed.ncbi.nlm.nih.gov/19535131
https://pubmed.ncbi.nlm.nih.gov/19535131
Autor:
Benedicte Paus, Svein Ove Semb, Svend Rand-Hendriksen, Kai Andersen, Odd Geiran, Jon Offstad, Rigmor Lundby, Lena Tjeldhorn
Publikováno v:
American journal of medical genetics. Part A. (17)
In monogenic disorders, correlation between genotype and phenotype is a premise for predicting prognosis in affected patients. Predictive genetic testing may enable prophylaxis and promote clinical follow-up. Although Marfan syndrome (MFS) is known a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51c576a12f97d11f2ea213820b2803ef
https://pubmed.ncbi.nlm.nih.gov/17663468
https://pubmed.ncbi.nlm.nih.gov/17663468