Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Lena Tanaka"'
Autor:
Ying Zheng, Xizhang Sun, Lena Tanaka, Keith B Elkon, Jie An, Andrea Kalus, Sarah Chung, Brandon Seaton, Ata Moshiri, Daniel Lih, Hari Krishnamurthy
Publikováno v:
Lupus Science and Medicine, Vol 8, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/def6645ee4904fce8a45d081ec0e50e3
Autor:
Brandon Seaton, Ying Zheng, Andrea Kalus, Lena Tanaka, Sarah Chung, Jie An, Xizhang Sun, Keith B. Elkon, Daniel Lih, Ata S. Moshiri, Hari Krishnamurthy
Publikováno v:
Lupus Science and Medicine, Vol 8, Iss Suppl 2 (2021)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cb7cfaf36fcedae0fe415ecacc149b0
https://doi.org/10.1136/lupus-2021-lupus21century.70
https://doi.org/10.1136/lupus-2021-lupus21century.70
Autor:
James A. Kuchenbecker, Jessica M. Snyder, Tomas Mustelin, Joyce Tai, Sladjana Skopelja-Gardner, Keith B. Elkon, Xizhang Sun, Lena Tanaka, Paul Kubes
Publikováno v:
Proceedings of the National Academy of Sciences. 118
Photosensitivity to ultraviolet (UV) light affects up to ∼80% of lupus patients. Sunlight exposure can exacerbate local as well as systemic manifestations of lupus, including nephritis, by mechanisms that are poorly understood. Here, we report that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::456136ebf73df537cb78ed93a9ae5e1f
https://doi.org/10.1073/pnas.2019097118
https://doi.org/10.1073/pnas.2019097118
Autor:
Sladjana Skopelja-Gardner, Keith B. Elkon, James A. Kuchenbecker, Jessica M. Snyder, Paul Kubes, Joyce Tai, Tomas Mustelin, Xizhang Sun, Lena Tanaka
Photosensitivity to ultraviolet (UV) light affects up to ~80% of lupus patients and can exacerbate local skin disease as well as systemic disease, including lupus nephritis. While neutrophils have been implicated in local tissue injury in lupus in re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f399ccb072917ae5044d2958c09c1131
https://doi.org/10.1101/2020.05.25.115204
https://doi.org/10.1101/2020.05.25.115204
Autor:
Keith B. Elkon, YuFeng Peng, Anne Davidson, Sladjana Skopelja-Gardner, Lucrezia Colonna, Lena Tanaka, David J. Salant, Xizhang Sun
Publikováno v:
Tissue Damage.
Background Lupus nephritis (LN) affects ∼70% of systemic lupus erythematosus (SLE) patients and is one of the main contributors to morbidity and mortality. While defective clearance of apoptotic cells (AC), immune complexes, and type 1 interferons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d4cdc012e5e45d741f73b0db3a50fd7c
https://doi.org/10.1136/lupus-2018-lsm.121
https://doi.org/10.1136/lupus-2018-lsm.121
Autor:
Xizhang Sun, Jinoh Kim, Nikita S. Kolhatkar, Edward A. Clark, Matthew B. Buechler, Craig P. Chappell, Keith B. Elkon, Lena Tanaka, Thereza Imanishi-Kari, Natalia V. Giltiay, Jessica A. Hamerman, Thomas H. Teal, Alice E. Wiedeman
Publikováno v:
The Journal of Experimental Medicine
Transgenic expression of TLR7 results in the expansion and hyperactivation of T1 B cells in response to endogenous RNA complexes, leading to increased autoantibody production.
Toll-like receptor (TLR), a ligand for single-stranded RNA, has been
Toll-like receptor (TLR), a ligand for single-stranded RNA, has been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5328468f1736fcc1295756d1ad47c4db
https://doi.org/10.1084/jem.20122798
https://doi.org/10.1084/jem.20122798
Increased Ribonuclease Expression Reduces Inflammation and Prolongs Survival in TLR7 Transgenic Mice
Autor:
Jessica A. Hamerman, Jeffrey A. Ledbetter, Nalini Agrawal, Thomas H. Teal, Denny Liggitt, Charles E. Alpers, Matthew B. Buechler, Lena Tanaka, Kelly L. Hudkins, Xizhang Sun, Keith B. Elkon, Alice E. Wiedeman, Silvia Bolland
Publikováno v:
The Journal of Immunology. 190:2536-2543
TLR7 activation is implicated in the pathogenesis of systemic lupus erythematosus. Mice that overexpress TLR7 develop a lupus-like disease with autoantibodies and glomerulonephritis and early death. To determine whether degradation of the TLR7 ligand
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28023e6f1ab801f1b07e90265f621e57
https://doi.org/10.4049/jimmunol.1202689
https://doi.org/10.4049/jimmunol.1202689
Autor:
Sladjana Skopelja-Gardner, YuFeng Peng, Lucrezia Colonna, Xizhang Sun, Lena Tanaka, David Salant, Keith B. Elkon
Publikováno v:
The Journal of Immunology. 200:45.12-45.12
Lupus nephritis (LN) is a common and serious complication of systemic lupus erythematosus (SLE). While defective clearance of apoptotic cells (AC) and immune complexes (IC) is implicated in LN pathogenesis, the precise way in which different compleme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9742152df28b65aebe939dee781b10af
https://doi.org/10.4049/jimmunol.200.supp.45.12
https://doi.org/10.4049/jimmunol.200.supp.45.12
Autor:
Masaoki Kawasumi, S.L. Wolin, Xizhang Sun, Lena Tanaka, D. Rokunohe, Keith B. Elkon, E. Chiou
Publikováno v:
Journal of Investigative Dermatology. 138:S14
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3eadc9ccb41dffe0fe94f33714cf0697
https://doi.org/10.1016/j.jid.2018.03.088
https://doi.org/10.1016/j.jid.2018.03.088
Autor:
Jerome A. Zack, Ren Sun, Jesusa M.G. Arevalo, Lena Tanaka, Steve W. Cole, Helen Brown, Hongyu Deng, Tonia L. Symensma, Zoran Galić, Margaret H. Chang, Alicia Collado-Hidalgo
Publikováno v:
Journal of virology. 79(21)
Reactivation of Kaposi's sarcoma-associated herpesvirus (KSHV) lytic replication is mediated by the viral RTA transcription factor, but little is known about the physiological processes controlling its expression or activity. Links between autonomic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e70001d05a0b21e7e72c18ec99445dc
https://pubmed.ncbi.nlm.nih.gov/16227274
https://pubmed.ncbi.nlm.nih.gov/16227274