Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Lena Staszewski"'
Autor:
Fernando Echeverri, Bianca Laita, Hong Xu, Raymond D. Smith, Nancy Hwang, Peter H. Li, Walter Keung, Lena Staszewski, Erika Patron, Andrew Patron, Jing Ling, Rachel D.A. Kimmich, Min Lu, Bryan D. Moyer, David Dahan, Dalia Kalabat, Jeff Yamamoto
Publikováno v:
Journal of Biological Chemistry. 283:11981-11994
The epithelial sodium channel (ENaC), a heterotrimeric complex composed of alpha, beta, and gamma subunits, belongs to the ENaC/degenerin family of ion channels and forms the principal route for apical Na(+) entry in many reabsorbing epithelia. Altho
Publikováno v:
Proceedings of the National Academy of Sciences. 101:14258-14263
The T1R receptors, a family of taste-specific class C G proteincoupled receptors, mediate mammalian sweet and umami tastes. The structure–function relationships of T1R receptors remain largely unknown. In this study, we demonstrate the different fu
Autor:
Anna Krones, Wen-Ming Yang, Yu-Der Wen, Valentina Perissi, Lena Staszewski, Christopher K. Glass, Edward Seto, Michael G. Rosenfeld
Publikováno v:
Proceedings of the National Academy of Sciences. 97:7202-7207
Acetylation and deacetylation of nucleosomal histones have profound effects on gene transcription in all eukaryotes. In humans, three highly homologous class I and four class II histone deacetylase (HDAC) enzymes have been identified to date. The cla
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 99(7)
The three members of the T1R class of taste-specific G protein-coupled receptors have been hypothesized to function in combination as heterodimeric sweet taste receptors. Here we show that human T1R2/T1R3 recognizes diverse natural and synthetic swee
Autor:
Riki Kurokawa, David W. Rose, Anna Krones, Valentina Perissi, Michael V. Milburn, Christopher K. Glass, Mill H. Lambert, Eileen M. McInerney, Lena Staszewski, Michael G. Rosenfeld
Retinoic acid and thyroid hormone receptors can act alternatively as ligand-independent repressors or ligand-dependent activators, based on an exchange of N-CoR or SMRT-containing corepressor complexes for coactivator complexes in response to ligands
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::250ff21e849c311e41f5568305cfe5b1
https://europepmc.org/articles/PMC317209/
https://europepmc.org/articles/PMC317209/
Publikováno v:
BMC Cell Biology. 5:34
Research on olfactory G-protein coupled receptors (GPCRs) has been severely impeded by poor functional expression in heterologous systems. Previously, we demonstrated that inefficient olfactory receptor (OR) expression at the plasma membrane is attri