Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Lena Schaffert"'
Autor:
Denise Bachmann, Upasana Pal, Julia A. Bockwoldt, Lena Schaffert, Robin Roentgen, Jochen Büchs, Jörn Kalinowski, Lars M. Blank, Till Tiso
Publikováno v:
Applied Microbiology, Vol 3, Iss 1, Pp 175-198 (2023)
Modern biotechnology benefits from the introduction of novel chassis organisms in remedying the limitations of already-established strains. For this, Paracoccus pantotrophus was chosen for in-depth assessment. Its unique broad metabolism and robustne
Externí odkaz:
https://doaj.org/article/987ec91d53104af68fc368e907fa57e0
Autor:
Lena Schaffert, Camilla März, Lisa Burkhardt, Julian Droste, David Brandt, Tobias Busche, Winfried Rosen, Susanne Schneiker-Bekel, Marcus Persicke, Alfred Pühler, Jörn Kalinowski
Publikováno v:
Microbial Cell Factories, Vol 18, Iss 1, Pp 1-16 (2019)
Abstract Background Actinoplanes sp. SE50/110 is a natural producer of acarbose. It has been extensively studied in the last decades, which has led to the comprehensive analysis of the whole genome, transcriptome and proteome. First genetic and micro
Externí odkaz:
https://doaj.org/article/06fc22940a8d490ea4714e557b6cfb5e
Autor:
Lena Schaffert, Susanne Schneiker-Bekel, Saskia Dymek, Julian Droste, Marcus Persicke, Tobias Busche, David Brandt, Alfred Pühler, Jörn Kalinowski
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
Actinoplanes sp. SE50/110 is the wild type of industrial production strains of the fine-chemical acarbose (acarviosyl-maltose), which is used as α-glucosidase inhibitor in the treatment of type II diabetes. Although maltose is an important building
Externí odkaz:
https://doaj.org/article/776f825ee4b74dc48d0e327737eceb89
Autor:
Yannick Branson, Simone Söltl, Carolin Buchmann, Ren Wei, Lena Schaffert, Christoffel P. S. Badenhorst, Lukas Reisky, Gernot Jäger, Uwe T. Bornscheuer
Publikováno v:
Angewandte Chemie. 135
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::856f3fb1674924bbcafc8c43ee4822af
https://doi.org/10.1002/ange.202216220
https://doi.org/10.1002/ange.202216220
Autor:
Yannick Branson, Simone Söltl, Carolin Buchmann, Ren Wei, Lena Schaffert, Christoffel P. S. Badenhorst, Lukas Reisky, Gernot Jäger, Uwe T. Bornscheuer
Publikováno v:
Angewandte Chemie (International ed. in English).
Enzymatic degradation and recycling can reduce the environmental impact of plastics. Despite decades of research, no enzymes for the efficient hydrolysis of polyurethanes have been reported. Whereas the hydrolysis of the ester bonds in polyester-poly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36b1ee7a64412caa52d1a4ba6d3d0c6e
https://pubmed.ncbi.nlm.nih.gov/36591907
https://pubmed.ncbi.nlm.nih.gov/36591907
Autor:
Lena Schaffert, Julian Droste, Alfred Pühler, Susanne Schneiker-Bekel, Timo Wolf, Martin Kulisch, Jörn Kalinowski
Publikováno v:
Applied Microbiology and Biotechnology
Abstract Actinoplanes sp. SE50/110 is the industrially relevant producer of acarbose, which is used in the treatment of diabetes mellitus. Recent studies elucidated the expression dynamics in Actinoplanes sp. SE50/110 during growth. From these data,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c429e7b6729d4bf10dd2a564720977d1
https://doi.org/10.1007/s00253-020-10923-2
https://doi.org/10.1007/s00253-020-10923-2
Autor:
Jessica Gierhake, Julian Droste, Alfred Pühler, Susanne Schneiker-Bekel, Lena Schaffert, Jörn Kalinowski, Marcus Persicke, Winfried Dipl Chem Dr Rosen
Publikováno v:
Applied Microbiology and Biotechnology
Actinoplanes sp. SE50/110 (ATCC 31044) is the wild type of industrial producer strains of acarbose. Acarbose has been used since the early 1990s as an inhibitor of intestinal human α-glucosidases in the medical treatment of type II diabetes mellitus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d506a25e60a8fd60a2da636dba7b2bb
http://europepmc.org/articles/PMC7275007
http://europepmc.org/articles/PMC7275007
Autor:
Lena, Schaffert, Matthias, Ruwe, Johanna, Milse, Katharina, Hanuschka, Vera, Ortseifen, Julian, Droste, David, Brandt, Laura, Schlüter, Yvonne, Kutter, Svenja, Vinke, Prisca, Viehöfer, Lucas, Jacob, Nils-Christian, Lübke, Eva, Schulte-Berndt, Carsten, Hain, Marten, Linder, Pascal, Schmidt, Lars, Wollenschläger, Tobias, Luttermann, Eric, Thieme, Julia, Hassa, Markus, Haak, Manuel, Wittchen, Almut, Mentz, Marcus, Persicke, Tobias, Busche, Christian, Rückert
Publikováno v:
International journal of systematic and evolutionary microbiology. 71(8)
Three novel corynebacterial species were isolated from soil sampled at a paddock in Vilsendorf, North Rhine-Westphalia, Germany. The strains were coccoid or irregular rod-shaped, catalase-positive and pale white to yellow-orange in colour. By whole g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2e54fa8da9a48a91f2a45153aed17781
https://pubmed.ncbi.nlm.nih.gov/34342562
https://pubmed.ncbi.nlm.nih.gov/34342562
Autor:
Julian Droste, Vera Ortseifen, Lena Schaffert, Marcus Persicke, Susanne Schneiker-Bekel, Alfred Pühler, Jörn Kalinowski
Background: Actinoplanes sp. SE50/110 is the natural producer of the diabetes mellitus drug acarbose, which is highly produced during the growth phase and ceases during the stationary phase. In previous works, the growth-dependency of acarbose format
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e36493c21d023986b7726c5c444623ab
https://doi.org/10.21203/rs.3.rs-41287/v2
https://doi.org/10.21203/rs.3.rs-41287/v2
Autor:
Lena, Schaffert, Lucas, Jacob, Susanne, Schneiker-Bekel, Marcus, Persicke, Camilla, März, Christian, Rückert, Alfred, Pühler, Jörn, Kalinowski
Publikováno v:
Microbiology resource announcements. 9(39)
The pSETT4 vector integrates into the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9ef8f6dff54f687f76c67fa6f7307550
https://pubmed.ncbi.nlm.nih.gov/32972929
https://pubmed.ncbi.nlm.nih.gov/32972929