Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Lena Rauch"'
Autor:
Kübra Kaygisiz, Lena Rauch-Wirth, Arghya Dutta, Xiaoqing Yu, Yuki Nagata, Tristan Bereau, Jan Münch, Christopher V. Synatschke, Tanja Weil
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Gene therapy via retroviral vectors holds great promise for treating a variety of serious diseases. It requires the use of additives to boost infectivity. Amyloid-like peptide nanofibers (PNFs) were shown to efficiently enhance retroviral ge
Externí odkaz:
https://doaj.org/article/a0c4158a505641c896321aabc2aea5ad
Autor:
Lena Rauch-Wirth, Alexander Renner, Kübra Kaygisiz, Tatjana Weil, Laura Zimmermann, Armando A. Rodriguez-Alfonso, Desiree Schütz, Sebastian Wiese, Ludger Ständker, Tanja Weil, Dominik Schmiedel, Jan Münch
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Chimeric antigen receptor (CAR)-T cell therapy is a groundbreaking immunotherapy for cancer. However, the intricate and costly manufacturing process remains a hurdle. Improving the transduction rate is a potential avenue to cut down costs and boost t
Externí odkaz:
https://doaj.org/article/c58f124f37b74c4d8faf65ee2ec09a7e
Autor:
Rüdiger Groß, Lívia Mesquita Dias Loiola, Leila Issmail, Nadja Uhlig, Valentina Eberlein, Carina Conzelmann, Lia‐Raluca Olari, Lena Rauch, Jan Lawrenz, Tatjana Weil, Janis A. Müller, Mateus Borba Cardoso, Andrea Gilg, Olivia Larsson, Urban Höglund, Sandra Axberg Pålsson, Anna Selch Tvilum, Kaja Borup Løvschall, Maria M. Kristensen, Anna‐Lena Spetz, Fortune Hontonnou, Marie Galloux, Thomas Grunwald, Alexander N. Zelikin, Jan Münch
Publikováno v:
Advanced Science, Vol 9, Iss 20, Pp n/a-n/a (2022)
Abstract Inhibitors of viral cell entry based on poly(styrene sulfonate) and its core–shell nanoformulations based on gold nanoparticles are investigated against a panel of viruses, including clinical isolates of SARS‐CoV‐2. Macromolecular inhi
Externí odkaz:
https://doaj.org/article/efb36e92da2449a5bac3fba657c93ca6
Autor:
Kübra Kaygisiz, Arghya Dutta, Lena Rauch-Wirth, Christopher V. Synatschke, Jan Münch, Tristan Bereau, Tanja Weil
Publikováno v:
Biomaterials Science
Amyloid-like nanofibers from self-assembling peptides can promote viral gene transfer for therapeutic applications. Traditionally, new sequences are discovered either from screening large libraries or by creating derivatives of known active peptides.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94774d67547e73b3824753ba8080b9a7
https://hdl.handle.net/21.11116/0000-000D-6BD6-A21.11116/0000-000D-5C51-1
https://hdl.handle.net/21.11116/0000-000D-6BD6-A21.11116/0000-000D-5C51-1
Autor:
Lia-Raluca Olari, Richard Bauer, Marta Gil Miró, Verena Vogel, Laura Cortez Rayas, Rüdiger Groß, Andrea Gilg, Raphael Klevesath, Armando A. Rodríguez Alfonso, Kübra Kaygisiz, Ulrich Rupp, Pradeep Pant, Joel Mieres-Pérez, Lena Steppe, Ramona Schäffer, Lena Rauch-Wirth, Carina Conzelmann, Janis A. Müller, Fabian Zech, Fabian Gerbl, Jana Bleher, Nico Preising, Ludger Ständker, Sebastian Wiese, Dietmar R. Thal, Christian Haupt, Hendrik R. A. Jonker, Manfred Wagner, Elsa Sanchez-Garcia, Tanja Weil, Steffen Stenger, Marcus Fändrich, Jens von Einem, Clarissa Read, Paul Walther, Frank Kirchhoff, Barbara Spellerberg, Jan Münch
Publikováno v:
Cellular and Molecular Life Sciences
Antimicrobial peptides (AMPs) are major components of the innate immune defense. Accumulating evidence suggests that the antibacterial activity of many AMPs is dependent on the formation of amyloid-like fibrils. To identify novel fibril forming AMPs,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bbe8105cd8417e0164731a868a792e3
https://www.ncbi.nlm.nih.gov/pubmed/37198527
https://www.ncbi.nlm.nih.gov/pubmed/37198527
Autor:
Tatjana Weil, Abbna Kirupakaran, My-Hue Le, Philipp Rebmann, Joel Mieres-Perez, Leila Issmail, Carina Conzelmann, Janis A. Müller, Lena Rauch, Andrea Gilg, Lukas Wettstein, Rüdiger Groß, Clarissa Read, Tim Bergner, Sandra Axberg Pålsson, Nadja Uhlig, Valentina Eberlein, Heike Wöll, Frank-Gerrit Klärner, Steffen Stenger, Beate M. Kümmerer, Hendrik Streeck, Giorgio Fois, Manfred Frick, Peter Braubach, Anna-Lena Spetz, Thomas Grunwald, James Shorter, Elsa Sanchez-Garcia, Thomas Schrader, Jan Münch
Publikováno v:
JACS Au
The COVID-19 pandemic caused by SARS-CoV-2 presents a global health emergency. Therapeutic options against SARS-CoV-2 are still very limited but urgently required. Molecular tweezers are supramolecular agents that destabilize the envelope of viruses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05e23a0fa6926dc7b1800439d47a6417