Výsledky vyhledávání - "Lena R. Bartell"

Microscale frictional strains determine chondrocyte fate in loaded cartilage

Autor: Edward D. Bonnevie, Lena R. Bartell, Naveen Jasty, Lawrence J. Bonassar, Lisa A. Fortier, Itai Cohen, M.L. Delco

Publikováno v: Journal of Biomechanics. 74:72-78

Mounting evidence suggests that altered lubricant levels within synovial fluid have acute biological consequences on chondrocyte homeostasis. While these responses have been connected to increased friction, the mechanisms behind this response remain

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68b11cf3eb6f51a26b46bc90cb3c14a0
https://doi.org/10.1016/j.jbiomech.2018.04.020

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Three-dimensional microscale flow of polymer coatings on glass during indentation

Autor: Lena R. Bartell, M. L. Sorensen, J. R. Matthews, Neil Y. C. Lin, G. S. Glaesemann, M. E. DeRosa, J. L. Lyon, M. J. Lockhart, D. A. Clark, Itai Cohen

Publikováno v: MRS Communications. 7:896-903

We present an indentation-scope that interfaces with confocal microscopy, enabling direct observation of the three-dimensional (3D) microstructural response of coatings on substrates. Using this method, we compared microns-thick polymer coatings on g

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7a60a09b357bfd07fb35ff2711facd7c
https://doi.org/10.1557/mrc.2017.114

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A rigidity percolation framework to explain how composition changes alter cartilage shear mechanics

Autor: Itai Cohen, Lena R. Bartell, Moumita Das, Lisa A. Fortier, Pancy Lwin, T. Wyse Jackson, Jonathan Michel, Lawrence J. Bonassar

Publikováno v: Osteoarthritis and Cartilage. 29:S115-S116

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c29c6dc0aa62cbfec01d219897739e4a
https://doi.org/10.1016/j.joca.2021.02.161

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The shear mechanics of enzymatically degraded articular cartilage are predicted by a rigidity percolation model

Autor: T. Wyse Jackson, Moumita Das, Itai Cohen, Lawrence J. Bonassar, Lena R. Bartell

Publikováno v: Osteoarthritis and Cartilage. 27:S163-S164

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d8f23e0a4b06fe78fafce661c577aabc
https://doi.org/10.1016/j.joca.2019.02.243

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In vitro culture increases mechanical stability of human tissue engineered cartilage constructs by prevention of microscale scaffold buckling

Autor: Itai Cohen, Lawrence J. Bonassar, Stephen Kennedy, Caroline Dugopolski, Jill M. Middendorf, Joseph Siemiatkoski, Sonya Shortkroff, Lena R. Bartell

Publikováno v: Journal of biomechanics. 64

Many studies have measured the global compressive properties of tissue engineered (TE) cartilage grown on porous scaffolds. Such scaffolds are known to exhibit strain softening due to local buckling under loading. As matrix is deposited onto these sc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36afc3b30bc949993b1d516b940f9704
https://pubmed.ncbi.nlm.nih.gov/28964498

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Multiscale Strain as a Predictor of Impact-Induced Fissuring in Articular Cartilage

Autor: Itai Cohen, Lena R. Bartell, Lawrence J. Bonassar, Corinne R. Henak

Mechanical damage is central to both initiation and progression of osteoarthritis (OA). However, specific causal links between mechanics and cartilage damage are incompletely understood, which results in an inability to predict failure. The lack of u

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9972063cffd0d1d7c534c2d8f607cc0
https://europepmc.org/articles/PMC5395913/

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