Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Lena Oppenländer"'
Autor:
Lena Oppenländer, Subarna Palit, Kerstin Stemmer, Tobias Greisle, Michael Sterr, Ciro Salinno, Aimée Bastidas-Ponce, Annette Feuchtinger, Anika Böttcher, Ansarullah, Fabian J. Theis, Heiko Lickert
Publikováno v:
Molecular Metabolism, Vol 54, Iss , Pp 101330- (2021)
Objective: The effectiveness of bariatric surgery in restoring β-cell function has been described in type-2 diabetes (T2D) patients and animal models for years, whereas the mechanistic underpinnings are largely unknown. The possibility of vertical s
Externí odkaz:
https://doaj.org/article/7aabff75bb9a47158f336af1b4279a0f
Autor:
Michal Grzybek, Matthias H. Tschöp, Oliver Plettenburg, Sara Bilekova, Lena Oppenländer, Johanna Siehler, Michael Sterr, Amir Morshedi, Sarah Homberg, Timo D. Müller, Aurelia Raducanu, Katharina Wißmiller, Felizitas Gräfin von Hahn, Ansarullah, Chirag Jain, Julius Wiener, Ünal Coskun, Johannes Beckers, Heiko Lickert, Gustav Collden, Fataneh Fathi Far, Silvia Schirge, Aimée Bastidas-Ponce, Christin Ahlbrecht, Annette Feuchtinger, Matthias Meier, Martin Irmler, Regina Feederle
Publikováno v:
Nature 590, 326–331 (2021)
Journal of Diabetes Investigation
Journal of Diabetes Investigation
Resistance to insulin and insulin-like growth factor 1 (IGF1) in pancreatic β-cells causes overt diabetes in mice; thus, therapies that sensitize β-cells to insulin may protect patients with diabetes against β-cell failure1–3. Here we identify a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28cffb16a5b0db7181203ac08e24aad3
https://doi.org/10.1038/s41586-021-03225-8
https://doi.org/10.1038/s41586-021-03225-8
Autor:
Johannes Beckers, Fabian J. Theis, Wolfgang Enard, Maren Büttner, Christoph Ziegenhain, Heiko Lickert, Fien M. Verhamme, Lena Oppenländer, Anika Böttcher, Sophie Tritschler, Oliver Eickelberg, Michael Sterr, Andrea C. Schamberger, Alexandra Aliluev, Martin Irmler, Steffen Sass, Ingo Burtscher
Publikováno v:
Nat. Cell Biol. 23, 23-31 (2021)
A detailed understanding of intestinal stem cell (ISC) self-renewal and differentiation is required to treat chronic intestinal diseases. However, the different models of ISC lineage hierarchy1–6 and segregation7–12 are subject to debate. Here, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b15847ba51c5ee6f9baf2b0a1d5082f
https://doi.org/10.1038/s41556-020-00617-2
https://doi.org/10.1038/s41556-020-00617-2
Autor:
Aimée Bastidas-Ponce, Lena Oppenländer, Anika Böttcher, Ansarullah, Fabian J. Theis, Tobias Greisle, Ciro Salinno, Subarna Palit, Annette Feuchtinger, Heiko Lickert, Kerstin Stemmer, Michael Sterr
Publikováno v:
Molecular Metabolism, Vol 54, Iss, Pp 101330-(2021)
Molecular Metabolism
Mol. Metab. 54:101330 (2021)
Molecular Metabolism
Mol. Metab. 54:101330 (2021)
Objective The effectiveness of bariatric surgery in restoring β-cell function has been described in type-2 diabetes (T2D) patients and animal models for years, whereas the mechanistic underpinnings are largely unknown. The possibility of vertical sl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::caa18575fb577b45efcc674a3caabd85
http://www.sciencedirect.com/science/article/pii/S2212877821001770
http://www.sciencedirect.com/science/article/pii/S2212877821001770
Autor:
Diego Benusiglio, Sophia Probst, Valery Grinevich, Yan Tang, Thomas Grund, Ferdinand Althammer, Inga D. Neumann, Lena Oppenländer
Publikováno v:
Psychoneuroendocrinology. 106:77-84
Chemogenetics provides cell type-specific remote control of neuronal activity. Here, we describe the application of chemogenetics used to specifically activate oxytocin (OT) neurons as representatives of a unique class of neuroendocrine cells. We inj
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31931a4427fc6b0f30cf5900549b0e71
https://doi.org/10.1016/j.psyneuen.2019.03.019
https://doi.org/10.1016/j.psyneuen.2019.03.019
Autor:
Johannes Beckers, Alexandra Aliluev, Sophie Tritschler, Michael Sterr, Alida S.D. Kindt, Malte D Luecken, Anika Böttcher, Julia Hinterdobler, Fabian J. Theis, Lena Oppenländer, Axel Walch, Kerstin Stemmer, Heiko Lickert, Na Sun, Tobias Greisle, Matthias H. Tschöp, Jan Krumsiek, Martin Irmler
Publikováno v:
Nat. Metab. 3, 1202-1216 (2021)
Tritschler, S.
Nature Metabolism
Tritschler, S.
Nature Metabolism
Excess nutrient uptake and altered hormone secretion in the gut contribute to a systemic energy imbalance, which causes obesity and an increased risk of type 2 diabetes and colorectal cancer. This functional maladaptation is thought to emerge at the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::767abad9568e2eb456aa33e6c7c17403
https://mediatum.ub.tum.de/doc/1639725/document.pdf
https://mediatum.ub.tum.de/doc/1639725/document.pdf
Autor:
Alexandra Aliluev, Fien M. Verhamme, Lena Oppenländer, Heiko Lickert, Maren Büttner, Sophie Tritschler, Johannes Beckers, Christoph Ziegenhain, Wolfgang Enard, Andrea C. Schamberger, Michael Sterr, Ingo Burtscher, Anika Böttcher, Oliver Eickelberg, Fabian J. Theis, Martin Irmler, Steffen Sass
SUMMARYA detailed understanding of intestinal stem cell (ISC) self-renewal and differentiation is required to better treat chronic intestinal diseases. However, different models of ISC lineage hierarchy1–6 and segregation7–12 are debated. Here we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::117073789a81aa6c4330c4b27d264a26
https://doi.org/10.1101/2020.08.12.247585
https://doi.org/10.1101/2020.08.12.247585