Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Lena Nitsch"'
Autor:
Caleb A. Lareau, Vincent Liu, Christoph Muus, Samantha D. Praktiknjo, Lena Nitsch, Pauline Kautz, Katalin Sandor, Yajie Yin, Jacob C. Gutierrez, Karin Pelka, Ansuman T. Satpathy, Aviv Regev, Vijay G. Sankaran, Leif S. Ludwig
Publikováno v:
Nat Protoc
Natural sequence variation within mitochondrial DNA (mtDNA) contributes to human phenotypes and may serve as natural genetic markers in human cells for clonal and lineage tracing. We recently developed a single-cell multi-omic approach, called ‘mit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6805399f4011424e33d01a02bff16c83
https://europepmc.org/articles/PMC10317201/
https://europepmc.org/articles/PMC10317201/
Autor:
Caleb A. Lareau, Sonia M. Dubois, Frank A. Buquicchio, Yu-Hsin Hsieh, Kopal Garg, Pauline Kautz, Lena Nitsch, Samantha D. Praktiknjo, Patrick Maschmeyer, Jeffrey M. Verboon, Jacob C. Gutierrez, Yajie Yin, Evgenij Fiskin, Wendy Luo, Eleni Mimitou, Christoph Muus, Rhea Malhotra, Sumit Parikh, Mark D. Fleming, Lena Oevermann, Johannes Schulte, Cornelia Eckert, Anshul Kundaje, Peter Smibert, Ansuman T. Satpathy, Aviv Regev, Vijay G. Sankaran, Suneet Agarwal, Leif S. Ludwig
Cells experience intrinsic and extrinsic pressures that affect their proclivity to expand and persistin vivo. In congenital disorders caused by loss-of-function mutations in mitochondrial DNA (mtDNA), metabolic vulnerabilities may result in cell-type
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a302a84cd1a039a55e3622f979122067
https://doi.org/10.1101/2022.11.20.517242
https://doi.org/10.1101/2022.11.20.517242
Autor:
Shourya S. Roy Burman, Rohan Sharma, Moritz Hunkeler, Peter Miller, Benjamin L. Ebert, Stefan Fröhling, Andrew A Guirguis, Claudia Scholl, Lena Nitsch, Priya Chudasama, Radosław P. Nowak, Hojong Yoon, Katherine A. Donovan, Cristina Di Genua, Charles Zou, Adam S. Sperling, Jessica A. Gasser, Eric S. Fischer, Jonathan M. Tsai, Mikolaj Slabicki, Jonas Koeppel
Publikováno v:
Nature
Effective and sustained inhibition of non-enzymatic oncogenic driver proteins is a major pharmacological challenge. The clinical success of thalidomide analogues demonstrates the therapeutic efficacy of drug-induced degradation of transcription facto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::593ed3b388c12a2bea67b34032dc473b
https://doi.org/10.1038/s41586-020-2925-1
https://doi.org/10.1038/s41586-020-2925-1
Autor:
Lena Nitsch, Patrizia Jensen, Hojong Yoon, Jonas Koeppel, Shourya Sonkar Roy Burman, Eric Sebastian Fischer, Claudia Scholl, Stefan Fröhling, Mikołaj Słabicki
Publikováno v:
Cell Reports Methods. 2:100193
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::32be918ffdb049aae1ad31d7e4991898
https://doi.org/10.1016/j.crmeth.2022.100193
https://doi.org/10.1016/j.crmeth.2022.100193
Autor:
Mikołaj Słabicki, Hojong Yoon, Jonas Koeppel, Lena Nitsch, Shourya S. Roy Burman, Cristina Di Genua, Katherine A. Donovan, Adam S. Sperling, Moritz Hunkeler, Jonathan M. Tsai, Rohan Sharma, Andrew Guirguis, Charles Zou, Priya Chudasama, Jessica A. Gasser, Peter G. Miller, Claudia Scholl, Stefan Fröhling, Radosław P. Nowak, Eric S. Fischer, Benjamin L. Ebert
Effective and sustained inhibition of non-enzymatic oncogenic driver proteins represents a major pharmacologic challenge. The clinical success of thalidomide analogs demonstrates the therapeutic efficacy of drug-induced degradation of transcription f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2659::aaa03efa24b32ea1a2fffde143552f85
https://zenodo.org/record/4412260
https://zenodo.org/record/4412260
Autor:
Karen Linnemannstöns, Lena Nitsch, Adi Danieli, Ferdinand Grawe, Andreas Wodarz, Pradhipa Karuna, Julia Christina Gross, Denise Müller, Mona Honemann-Capito, Jeanette Clarissa Kittel, Leonie Witte
Publikováno v:
Development (Cambridge, England)
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Morphogens are important signalling molecules for tissue development and their secretion requires tight regulation. In the wing imaginal disc of flies, the morphogen Wnt/Wingless is apically presented by the secreting cell and re-internalized before
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a69b596948233d89374a84f8537bb4f7
https://doi.org/10.1242/dev.185421
https://doi.org/10.1242/dev.185421
Autor:
Leonie Witte, Denise Müller, Andreas Wodarz, Mona Honemann-Capito, Adi Danieli, Ferdi Grawe, Pradhipa Karuna M, Julia Christina Gross, Lena Nitsch, Jeanette Clarissa Kittel, Karen Linnemannstöns
Protein trafficking in the secretory pathway, for example the secretion of Wnt proteins, requires tight regulation. These ligands activate Wnt signaling pathways and are crucially involved in development and disease. Wnt is transported to the plasma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::558b2904fae2e3242df36e8af09a2d1b
https://doi.org/10.1101/485565
https://doi.org/10.1101/485565