Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Lena Merkel"'
Autor:
Linus A. Völker, Jessica Kaufeld, Gesa Balduin, Lena Merkel, Lucas Kühne, Dennis A. Eichenauer, Thomas Osterholt, Holger Hägele, Martin Kann, Franziska Grundmann, Benedikt Kolbrink, Kevin Schulte, Anja Gäckler, Andreas Kribben, Kristina Boss, Sebastian A. Potthoff, Lars C. Rump, Tilman Schmidt, Anja S. Mühlfeld, Karsten Schulmann, Matthias Hermann, Jens Gaedeke, Kristin Sauerland, Jörn Bramstedt, Ulrich P. Hinkel, Wolfgang Miesbach, Frederic Bauer, Timm H. Westhoff, Heike Bruck, Veronika Buxhofer-Ausch, Tobias J. Müller, Ralph Wendt, Ana Harth, Adrian Schreiber, Evelyn Seelow, Markus Tölle, Christopher Gohlisch, Markus Bieringer, Gesa Geuther, Wolfram J. Jabs, Michael Fischereder, Anke von Bergwelt-Baildon, Ulf Schönermarck, Paul Knoebl, Jan Menne, Paul T. Brinkkoetter, Fedai Özcan, Silke Markau, Matthias Girndt, Helmut Felten, Martin Hausberg, Marcus Brand, Jens Gerth, Martin Bommer, Stefan Zschiedrich, Johanna Schneider, Saban Elitok, Alexander Gawlik, Vedat Schwenger, Maximilian Roeder, Jörg Radermacher, Anke Morgner, Regina Herbst, Charis von Auer
Publikováno v:
Journal of Thrombosis and Haemostasis. 21:559-572
BACKGROUND: The von Willebrand factor-directed nanobody caplacizumab has greatly changed the treatment of immune thrombotic thrombocytopenic purpura (iTTP) in recent years. Data from randomized controlled trials established efficacy and safety. OBJEC
Autor:
Anna Lena Merkel, Lena Kastl, Adina Vultur, Kathrin Wähler, Batool Shannan, Matthias Ocker, Wolfgang J. Parak, Klaus Harms, Sandra Dieckmann, Timo Völker, Anja Kastl, Meenhard Herlyn, Eric Meggers
Publikováno v:
ChemMedChem. 8:924-927
Metal complexes constitute an attractive class of compounds for applications in medicinal chemistry and chemical biology due to features such as unusual reactivities, tunable ligand exchange kinetics, stereochemical diversity, structural complexity,
Publikováno v:
Expert opinion on investigational drugs. 21(4)
Inhibition of protein kinases has become a standard of modern clinical oncology. PIM1 belongs to a novel class of serine/threonine kinases with distinct molecular and biochemical features regulating various oncogenic pathways, for example hypoxia res
Autor:
Ansgar Schmidt, Matthias Ocker, Daniel Neureiter, Beate Alinger, Roberta Montalbano, Anna Lena Merkel, Karl Quint, Pietro Di Fazio
Publikováno v:
Experimental cell research. 318(15)
Inhibitors of protein deacetylases represent a novel therapeutic option for cancer diseases due to their effects on transcriptional regulation by interfering with histones acetylation and on several other cellular pathways. Recently, their ability to
Autor:
Alexander Wilbuer, Anja Kastl, Matthias Ocker, Pietro Di Fazio, Li Feng, Eric Meggers, Anna Lena Merkel
Publikováno v:
Chemical communications (Cambridge, England). 48(13)
A metal complex is identified in which the metal fulfills two independent functions: as a structural scaffold for the specific molecular recognition of protein kinases resulting in antiangiogenic properties, together with a visible-light-induced phot