Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Lena Jaki"'
Autor:
Julian Fischer, Ariana Fedotova, Lena Jaki, Erwan Sallard, Anja Erhardt, Jonas Fuchs, Zsolt Ruzsics
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 32, Iss 2, Pp 101241- (2024)
While recombinant adenoviruses (rAds) are widely used in both laboratory and medical gene transfer, library-based applications using this vector platform are not readily available. Recently, we developed a new method, the CRISPR-Cas9 mediated in vivo
Externí odkaz:
https://doaj.org/article/3d35861727e64f9e8b96af043b0c6bc8
Autor:
Lena Jaki, Sebastian Weigang, Lisa Kern, Stefanie Kramme, Antoni G. Wrobel, Andrea B. Grawitz, Philipp Nawrath, Stephen R. Martin, Theo Dähne, Julius Beer, Miriam Disch, Philipp Kolb, Lisa Gutbrod, Sandra Reuter, Klaus Warnatz, Martin Schwemmle, Steven J. Gamblin, Elke Neumann-Haefelin, Daniel Schnepf, Thomas Welte, Georg Kochs, Daniela Huzly, Marcus Panning, Jonas Fuchs
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Monoclonal antibodies (mAbs) directed against the spike of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are effective therapeutic options to combat infections in high-risk patients. Here, we report the adaptation of SARS-CoV-
Externí odkaz:
https://doaj.org/article/d61edc8bae2d4d3c8f29f4fd3b6b89ba
Autor:
Tamara Kaleta, Lisa Kern, Samuel Leandro Hong, Martin Hölzer, Georg Kochs, Julius Beer, Daniel Schnepf, Martin Schwemmle, Nena Bollen, Philipp Kolb, Magdalena Huber, Svenja Ulferts, Sebastian Weigang, Gytis Dudas, Alice Wittig, Lena Jaki, Abdou Padane, Adamou Lagare, Mounerou Salou, Egon Anderson Ozer, Ndodo Nnaemeka, John Kofi Odoom, Robert Rutayisire, Alia Benkahla, Chantal Akoua-Koffi, Abdoul-Salam Ouedraogo, Etienne Simon-Lorière, Vincent Enouf, Stefan Kröger, Sébastien Calvignac-Spencer, Guy Baele, Marcus Panning, Jonas Fuchs
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
The A.27 SARS-CoV-2 lineage spread globally in 2021 but did not become dominant. Here, the authors show that A.27 shares some mutations in the spike gene that are present in variants of concern, but lacks the D614G mutation, indicating independent ev
Externí odkaz:
https://doaj.org/article/95413bc995ee4d938afb0a7f4c3cfaa7
Autor:
Julia Lang-Meli, Jonas Fuchs, Philipp Mathé, Hsi-en Ho, Lisa Kern, Lena Jaki, Giuseppe Rusignuolo, Susanne Mertins, Vivien Somogyi, Christoph Neumann-Haefelin, Frederik Trinkmann, Michael Müller, Robert Thimme, Markus Umhau, Isabella Quinti, Dirk Wagner, Marcus Panning, Charlotte Cunningham-Rundles, Katharina Laubner, Klaus Warnatz
Publikováno v:
Journal of Clinical Immunology
Patients with primary antibody deficiency are at risk for severe and in many cases for prolonged COVID-19. Convalescent plasma treatment of immunocompromised individuals could be an option especially in countries with limited access to monoclonal ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ba1dab979ef23eb52815765efc6dc12
http://hdl.handle.net/11573/1611980
http://hdl.handle.net/11573/1611980
Autor:
Daniel, Hornuss, Theo, Daehne, Veronika, Goetz, Matthias, Mueller, Susanne, Usadel, Alexandra, Lorz, Maja, Mockenhaupt, Daniela, Huzly, Sibylle, Bierbaum, Jonas, Fuchs, Lena, Jaki, Valeria, Falcone, Georg, Kochs, Marcus, Panning, Siegbert, Rieg
Publikováno v:
Clinical Microbiology and Infection. 29:112.e5-112.e9
Since April 2022, increasing numbers of monkeypox (MPX) cases have been reported outside endemic areas as part of an international outbreak. Our study shows aspects of clinical manifestations as well as epidemiological and virological features impact
Autor:
Martin Schwemmle, Guy Baele, Georg Kochs, Etienne Simon-Loriere, Sebastian Weigang, Martin Hölzer, Samuel L. Hong, Julius Beer, Jonas Fuchs, Mounerou Salou, Alice Wittig, Philipp Kolb, Lisa Kern, Stefan Kröger, Adamou Lagare, Abdou Padane, Ndodo Nnaemeka, Magdalena Huber, Gytis Dudas, Lena Jaki, Svenja Ulferts, Daniel Schnepf, Abdoul-Salam Ouédraogo, Egon Ozer, Alia Benkahla, Tamara Kaleta, Sébastien Calvignac-Spencer, Vincent Enouf, Robert Rutayisire, Nena Bollen, John Odoom, Marcus Panning, Chantal Akoua-Koffi
Publikováno v:
Nature communications. 13(1)
In spring 2021, an increasing number of infections was observed caused by the hitherto rarely described SARS-CoV-2 variant A.27 in south-west Germany. From December 2020 to June 2021 this lineage has been detected in 31 countries. Phylogeographic ana