Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Lena Hauberg-Lotte"'
Autor:
Amin Ardestani, Sijia Li, Karthika Annamalai, Blaz Lupse, Shirin Geravandi, Aleksandra Dobrowolski, Shan Yu, Siying Zhu, Tyler D. Baguley, Murali Surakattula, Janina Oetjen, Lena Hauberg-Lotte, Raquel Herranz, Sushil Awal, Delsi Altenhofen, Van Nguyen-Tran, Sean Joseph, Peter G. Schultz, Arnab K. Chatterjee, Nikki Rogers, Matthew S. Tremblay, Weijun Shen, Kathrin Maedler
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Type 1 as well as type 2 diabetes are characterized by a loss of insulin-producing β-cells. Here the authors show that the FDA-approved drug neratinib has beneficial effects on β-cell survival, insulin secretion, and glycemic control in mouse model
Externí odkaz:
https://doaj.org/article/627d0ae36e6e4ac994b3607b5e658ae4
Autor:
Charlotte Janßen, Tobias Boskamp, Jean Le’Clerc Arrastia, Daniel Otero Baguer, Lena Hauberg-Lotte, Mark Kriegsmann, Katharina Kriegsmann, Georg Steinbuß, Rita Casadonte, Jörg Kriegsmann, Peter Maaß
Publikováno v:
Cancers, Vol 14, Iss 24, p 6181 (2022)
Artificial intelligence (AI) has shown potential for facilitating the detection and classification of tumors. In patients with non-small cell lung cancer, distinguishing between the most common subtypes, adenocarcinoma (ADC) and squamous cell carcino
Externí odkaz:
https://doaj.org/article/11d22729f861406ea83017b8d8584f5a
Autor:
Jean Le’Clerc Arrastia, Nick Heilenkötter, Daniel Otero Baguer, Lena Hauberg-Lotte, Tobias Boskamp, Sonja Hetzer, Nicole Duschner, Jörg Schaller, Peter Maass
Publikováno v:
Journal of Imaging, Vol 7, Iss 4, p 71 (2021)
Accurate and fast assessment of resection margins is an essential part of a dermatopathologist’s clinical routine. In this work, we successfully develop a deep learning method to assist the dermatopathologists by marking critical regions that have
Externí odkaz:
https://doaj.org/article/4ce6abaf685c4ae9b692fe1cc3c512f4
Autor:
Lena Hauberg-Lotte, Hannah Klingenberg, Christian Scharf, Melanie Böhm, Jörg Plessl, Frauke Friedrich, Uwe Völker, Anke Becker, Barbara Reinhold-Hurek
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e30421 (2012)
BackgroundBacterial communication is involved in regulation of cellular mechanisms such as metabolic processes, microbe-host interactions or biofilm formation. In the nitrogen-fixing model endophyte of grasses Azoarcus sp. strain BH72, known cell-cel
Externí odkaz:
https://doaj.org/article/a2fd387757334b7ba27bd9f871805b57
Autor:
Charlotte Janßen, Tobias Boskamp, Lena Hauberg‐Lotte, Jens Behrmann, Sören‐Oliver Deininger, Mark Kriegsmann, Katharina Kriegsmann, Georg Steinbuß, Hauke Winter, Thomas Muley, Rita Casadonte, Jörg Kriegsmann, Peter Maaß
Publikováno v:
Proteomics. Clinical applicationsREFERENCES. 16(4)
Subtyping of the most common non-small cell lung cancer (NSCLC) tumor types adenocarcinoma (ADC) and squamous cell carcinoma (SqCC) is still a challenge in the clinical routine and a correct diagnosis is crucial for an adequate therapy selection. Mat
Autor:
Tobias Boskamp, Lena Hauberg-Lotte, Peter Maass, Sören Deininger, Jörg Kriegsmann, Rita Casadonte
Publikováno v:
Analytical chemistry. 93(30)
Matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI MSI) is an established tool for the investigation of formalin-fixed paraffin-embedded (FFPE) tissue samples and shows a high potential for applications in clinical research
Publikováno v:
Mathematics in Industry ISBN: 9783030814540
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0cd1a23a244657814c90c60d7a3cc196
https://doi.org/10.1007/978-3-030-81455-7_17
https://doi.org/10.1007/978-3-030-81455-7_17
Autor:
Tobias Boskamp, Jan Hendrik Kobarg, Lena Hauberg-Lotte, Delf Lachmund, Peter Maass, Jörg Kriegsmann, Rita Casadonte
Publikováno v:
Analytical chemistry. 92(1)
Matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI MSI) is an established tool for the investigation of formalin fixed paraffin embedded (FFPE) tissue samples and shows a high potential for applications in clinical research
Autor:
Mark Kriegsmann, Katharina Kriegsmann, Delf Lachmund, Dennis Trede, Tobias Boskamp, Lena Hauberg-Lotte, Annette Peter, Janina Oetjen, Peter Maass, Jörg Kriegsmann, Rita Casadonte, Yovany Cordero Hernandez
Publikováno v:
Proteomics. Clinical applications. 13(1)
Purpose To develop a mass spectrometry imaging (MSI) based workflow for extracting m/z values related to putative protein biomarkers and using these for reliable tumor classification. Experimental design Given a list of putative breast and ovarian ca
Autor:
Lena Hauberg-Lotte, Günther Ernst, Dennis Trede, Michael Becker, von Eggeling F, Orlando Guntinas-Lichius, Theodore Alexandrov
Publikováno v:
Head & Neck. 37:1014-1021
Background Despite efforts in localization of key proteins using immunohistochemistry, the complex proteomic composition of pleomorphic adenomas has not yet been characterized. Matrix-assisted laser desorption/ionization imaging mass spectrometry (MA