Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Lena Erlandsson"'
Autor:
Lena Erlandsson, Lena Ohlsson, Zahra Masoumi, Mimmi Rehnström, Tina Cronqvist, Lars Edvinsson, Stefan R. Hansson
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Preeclampsia (PE) is a pregnancy syndrome characterized by hypertension and organ damage manifesting after 20 gestational weeks. The etiology is of multifactorial origin, where placental stress causes increased levels of placenta-derived ext
Externí odkaz:
https://doaj.org/article/51db3ac41da54a339005083b4ddb8bd5
Publikováno v:
Hypertension in Pregnancy, Vol 43, Iss 1 (2024)
ABSTRACTBackground Predicting severe preeclampsia with need for intensive care is challenging. To better predict high-risk pregnancies to prevent adverse outcomes such as eclampsia is still an unmet need worldwide. In this study we aimed to develop a
Externí odkaz:
https://doaj.org/article/902fb8c1b1ce409693b07bc16d50e4be
Autor:
Sofie Meijer, Elena Pasquinelli, Sonia Renzi, Shahram Lavasani, Mehrnaz Nouri, Lena Erlandsson, Duccio Cavalieri, Stefan R. Hansson
Publikováno v:
Biomolecules, Vol 13, Iss 2, p 346 (2023)
Preeclampsia is a severe pregnancy-related inflammatory disease without an effective treatment. The pathophysiology remains partly unknown. However, an increased inflammatory response and oxidative stress are part of the maternal systemic reaction. R
Externí odkaz:
https://doaj.org/article/0da19b72957d40cc934e2f28fc6c59b6
Autor:
Yumjirmaa Mandakh, Anna Oudin, Lena Erlandsson, Christina Isaxon, Stefan R. Hansson, Karin Broberg, Ebba Malmqvist
Publikováno v:
Frontiers in Toxicology, Vol 3 (2021)
Background: Studies have shown that ambient air pollution is linked to preeclampsia (PE), possibly via generation of oxidative stress in the placenta. Telomere length and mitochondrial DNA copy number (mtDNAcn) are sensitive to oxidative stress damag
Externí odkaz:
https://doaj.org/article/fecdc492ac77435c83a64fdbf93fcc84
Autor:
Karin Engström, Yumjirmaa Mandakh, Lana Garmire, Zahra Masoumi, Christina Isaxon, Ebba Malmqvist, Lena Erlandsson, Stefan R. Hansson
Publikováno v:
Toxics, Vol 9, Iss 12, p 338 (2021)
Exposure to ambient air pollution during pregnancy has been associated with an increased risk of preeclampsia (PE). Some suggested mechanisms behind this association are changes in placental DNA methylation and gene expression. The objective of this
Externí odkaz:
https://doaj.org/article/68cdf7c27b0c4a8bbbe14e05667f609d
Autor:
Åsa Nääv, Lena Erlandsson, Christina Isaxon, Eleonor Åsander Frostner, Johannes Ehinger, Moa K. Sporre, Annette M. Krais, Bo Strandberg, Thomas Lundh, Eskil Elmér, Ebba Malmqvist, Stefan R. Hansson
Publikováno v:
Frontiers in Endocrinology, Vol 11 (2020)
Objective: Epidemiological studies have found air pollution to be a driver of adverse pregnancy outcomes, including gestational diabetes, low term birth weight and preeclampsia. It is unknown what biological mechanisms are involved in this process. A
Externí odkaz:
https://doaj.org/article/f606257b414e4486b152249ac5dfdef4
Autor:
Lina Youssef, Lena Erlandsson, Bo Åkerström, Jezid Miranda, Cristina Paules, Francesca Crovetto, Fatima Crispi, Eduard Gratacos, Stefan R Hansson
Publikováno v:
PLoS ONE, Vol 15, Iss 9, p e0239030 (2020)
Hemopexin and α1-microglobulin act as scavengers to eliminate free heme-groups responsible for hemoglobin-induced oxidative stress. The present study evaluated maternal and fetal plasma concentrations of these scavengers in the different phenotypes
Externí odkaz:
https://doaj.org/article/45d7176e13f24d69a73ad9d2ff40b357
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 7, p 3357 (2021)
Preeclampsia (PE) is a pregnancy disorder associated with placental dysfunction and elevated fetal hemoglobin (HbF). Early in pregnancy the placenta harbors hematopoietic stem and progenitor cells (HSPCs) and is an extramedullary source of erythropoi
Externí odkaz:
https://doaj.org/article/a0942670df38446fac99195487075fe3
Autor:
Mary Familari, Åsa Nääv, Lena Erlandsson, Robb U de Iongh, Christina Isaxon, Bo Strandberg, Thomas Lundh, Stefan R Hansson, Ebba Malmqvist
Publikováno v:
PLoS ONE, Vol 14, Iss 7, p e0218799 (2019)
Ambient air pollution is considered a major environmental health threat to pregnant women. Our previous work has shown an association between exposure to airborne particulate matter (PM) and an increased risk of developing pre-eclamspia. It is now re
Externí odkaz:
https://doaj.org/article/d6d13cb7ccd1482cb08a9b1b19d997d4
Autor:
Tsehayneh Kelemu, Lena Erlandsson, Daniel Seifu, Markos Abebe, Sisay Teklu, Jill R. Storry, Stefan R. Hansson
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 16, p 5837 (2020)
Preeclampsia (PE) is a human specific syndrome with unknown etiology causing maternal and fetal morbidities and mortalities. In PE, maternal inflammatory responses are more exaggerated if the fetus is male than female. Other pregnancy complications s
Externí odkaz:
https://doaj.org/article/dc17b10ac7eb4766b1f9c25c3c3afce5