Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Lena Deuper"'
Autor:
Marina Kaiser, Timo H. Lüdtke, Lena Deuper, Carsten Rudat, Vincent M. Christoffels, Andreas Kispert, Mark-Oliver Trowe
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Inner hair cells are essential for hearing but the molecular drivers of their differentiation have remained enigmatic. Here, the authors show that the transcription factor TBX2 has a key function in inducing and maintaining inner hair cell fate.
Externí odkaz:
https://doaj.org/article/a1ed0988f76a43e0ad9f7df5cbd56ffb
Autor:
Jennifer Kurz, Anna-Carina Weiss, Timo H.-W. Lüdtke, Lena Deuper, Mark-Oliver Trowe, Hauke Thiesler, Herbert Hildebrandt, Joerg Heineke, Stephen A. Duncan, Andreas Kispert
Publikováno v:
Development. 149
Smooth muscle cells (SMCs) are a crucial component of the mesenchymal wall of the ureter, as they account for the efficient removal of the urine from the renal pelvis to the bladder by means of their contractile activity. Here, we show that the zinc-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bdaec208a31d331c1d6429e767c9f2e
https://doi.org/10.1242/dev.200522
https://doi.org/10.1242/dev.200522
Autor:
Lena Deuper, Max Meuser, Hauke Thiesler, Ulrich W. H. Jany, Carsten Rudat, Herbert Hildebrandt, Mark-Oliver Trowe, Andreas Kispert
Publikováno v:
Development (Cambridge, England). 149(17)
The coordinated development of the mesenchymal and epithelial progenitors of the murine ureter depends on a complex interplay of diverse signaling activities. We have recently shown that epithelial FGFR2 signaling regulates stratification and differe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c02155dda0386de1d9047052459d7c2b
https://pubmed.ncbi.nlm.nih.gov/36094016
https://pubmed.ncbi.nlm.nih.gov/36094016
Autor:
Max Meuser, Lena Deuper, Carsten Rudat, Nurullah Aydoğdu, Hauke Thiesler, Patricia Zarnovican, Herbert Hildebrandt, Mark-Oliver Trowe, Andreas Kispert
Publikováno v:
Development. 149
The patterned array of basal, intermediate and superficial cells in the urothelium of the mature ureter arises from uncommitted epithelial progenitors of the distal ureteric bud. Urothelial development requires signaling input from surrounding mesenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7b99f927da9aee2b01b28de1653722d
https://doi.org/10.1242/dev.200021
https://doi.org/10.1242/dev.200021
Autor:
Jennifer Kurz, Anna-Carina Weiss, Hauke Thiesler, Fairouz Qasrawi, Lena Deuper, Jaskiran Kaur, Carsten Rudat, Timo H. Lüdtke, Irina Wojahn, Herbert Hildebrandt, Mark-Oliver Trowe, Andreas Kispert
Publikováno v:
Development (Cambridge, England). 149(4)
The contractile phenotype of smooth muscle cells (SMCs) is transcriptionally controlled by a complex of the DNA-binding protein SRF and the transcriptional co-activator MYOCD. The pathways that activate expression of Myocd and of SMC structural genes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c3b1f29b816fad34da3a013120fde21
https://pubmed.ncbi.nlm.nih.gov/35103284
https://pubmed.ncbi.nlm.nih.gov/35103284
Autor:
Johanna Flach, Dieter Kube, Zuzanna Rydzynska, Gerburg M. Wulf, Bjoern Chapuy, Raphael Koch, Sabrina Becker, Ursula Sinzig, Andreas Leha, Brigitte Maruschak, Kamil Bojarczuk, Pablo Trigo-Mouriño, Christina Kiecke, Gerald Wulf, Christian Griesinger, Mateus de Oliveira Taveira, Sascha Dierks, Hanibal Bohnenberger, Holger Bastians, Vivek Venkataramani, Frederike von Bonin, Eva Schaefer, Lorenz Trümper, Lena Deuper
Publikováno v:
Molecular cancer research : MCR. 18(6)
Tightly regulated activity of the transcription factor MYC is essential for orderly cell proliferation. Upon deregulation, MYC elicits and promotes cancer progression. Proteasomal degradation is an essential element of MYC regulation, initiated by ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e49d9fba8dc865c39cc03f459cf450c4
https://pubmed.ncbi.nlm.nih.gov/32161139
https://pubmed.ncbi.nlm.nih.gov/32161139
Autor:
Jennifer Kurz, Patrick Blank, Timo H. Lüdtke, Lena Deuper, Thomas von Hahn, Andreas Kispert, Marc-Jens Kleppa, Marina Kaiser, Anna-Carina Weiss, Tamrat M. Mamo, Tobias Bohnenpoll, Mark-Oliver Trowe, Rui Costa, Rannar Airik
Publikováno v:
The Journal of pathology. 248(4)
The establishment of the peristaltic machinery of the ureter is precisely controlled to cope with the onset of urine production in the fetal kidney. Retinoic acid (RA) has been identified as a signal that maintains the mesenchymal progenitors of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01be0211606371a31a16050db8ff7d20
https://pubmed.ncbi.nlm.nih.gov/30916783
https://pubmed.ncbi.nlm.nih.gov/30916783
Autor:
Kaiser, Marina, Lüdtke, Timo H., Deuper, Lena, Rudat, Carsten, Christoffels, Vincent M., Kispert, Andreas, Trowe, Mark-Oliver
Publikováno v:
Nature Communications; 12/9/2022, Vol. 13 Issue 1, p1-12, 12p
Autor:
Weiss, Anna‐Carina, Bohnenpoll, Tobias, Kurz, Jennifer, Blank, Patrick, Airik, Rannar, Lüdtke, Timo H, Kleppa, Marc‐Jens, Deuper, Lena, Kaiser, Marina, Mamo, Tamrat M, Costa, Rui, Hahn, Thomas, Trowe, Mark‐Oliver, Kispert, Andreas
Publikováno v:
Journal of Pathology; Aug2019, Vol. 248 Issue 4, p452-463, 12p