Zobrazeno 1 - 6 of 6 pro vyhledávání: '"Lena C. E. Ohlson"'
1
Loss of Nuclear p53 Protein in Preneoplastic Rat Hepatocytes Is Accompanied by Mdm2 and Bcl-2 Overexpression and by Defective Response to DNA Damage In Vivo
Autor: John H. N. Meerman, Gerard J. Mulder, Inger Porsch-Hällström, Lennart Eriksson, Hilde E. van Gijssel, Ulla-Britta Torndal, Lena C. E. Ohlson
Publikováno v: Hepatology. 32:701-710
Previous studies have indicated that isolated preneoplastic rat hepatocytes in vitro fail to induce nuclear p53 protein and fail to block replication in response to genotoxic compounds. This suggests that defects in the protection of genomic integrit
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbb9a5a5978c170f08f7379e03432440
https://doi.org/10.1053/jhep.2000.17660
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2
Inhibition ofin vivorat liver regeneration by 2-acetylaminofluorene affects the regulation of cell cycle-related proteins
Autor: Lena Koroxenidou, Lena C. E. Ohlson, Inger Porsch Hällström
Publikováno v: Hepatology. 27:691-696
The effects of dietary 2-acetylaminofluorene (2-AAF) on cell cycle-related proteins was studied in regenerating livers from male Wistar rats. The levels of cyclins, cyclin dependent kinases (cdks), and related proteins were studied at different times
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e2fe936e37dd4d74c641cf7851a019c5
https://doi.org/10.1002/hep.510270309
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4
Mitoinhibitory effects of the tumor promoter 2-acetylaminofluorene in rat liver: loss of E2F-1 and E2F-3 expression and cdk 2 kinase activity in late G1
Autor: Inger Porsch-Hällström, Lena Koroxenidou, Lena C. E. Ohlson
Publikováno v: Journal of hepatology. 40(6)
Examine the mitoinhibitory effect of the liver tumor promoter 2-acetylaminofluorene (2-AAF) in vivo, with focus on the proteins regulating G1- and S progression.cdk 2 kinase assay to examine histone H1 phosphorylation. cdk 4 kinase assay to examine w
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e9238575111ed3c2edc6f03497fb10c
https://pubmed.ncbi.nlm.nih.gov/15158336
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5
Nuclear Protein Binding to the AP-1 and CRE Sites During Sex-Differentiated Promotion of Rat Liver Carcinogenesis
Autor: Lena C. E. Ohlson, Inger Porsch Hällström
Publikováno v: Hormonal Carcinogenesis II ISBN: 9781461275060
The binding of liver nuclear proteins to the AP-1 and CRE sites was studied. Decreased binding to both sites was observed in liver extracts from 2-AAF-promoted and unpromoted male and female rats initiated with DEN. Overall, binding to the AP-1 and C
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::01b7cd1220bbf05d2851e7f6f6b9947e
https://doi.org/10.1007/978-1-4612-2332-0_61
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6
Regulation of Growth-Associated Nuclear Transcription Factors During Growth Hormone-Regulated, Sex-Differentiated Rat Liver Carcinogenesis
Autor: Agneta Blanck, Dezhong Liao, Lena C. E. Ohlson, Inger Porsch Hällström
Publikováno v: Hormonal Carcinogenesis II ISBN: 9781461275060
The incidence of hepatocellular carcinoma (HCC) in man is markedly sex differentiated, with a higher frequency in men than in women, in both high-risk and low-incidence areas (1, 2). Furthermore, both androgens and synthetic estrogens are potential r
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2d177306a34efea12c54e4496978a357
https://doi.org/10.1007/978-1-4612-2332-0_27
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