Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Lena Behrmann"'
Autor:
Malwine J. Barz, Lena Behrmann, Danaëlle Capron, Gabriele Zuchtriegel, Fabio D. Steffen, Leo Kunz, Yang Zhang, Iria Jimenez Vermeerbergen, Blerim Marovca, Moritz Kirschmann, Antonia Zech, César Nombela-Arrieta, Urs Ziegler, Timm Schroeder, Beat Bornhauser, Jean-Pierre Bourquin
Publikováno v:
Haematologica, Vol 108, Iss 5 (2022)
Persistence of residual disease after induction chemotherapy is a strong predictor of relapse in acute lymphoblastic leukemia (ALL). The bone marrow microenvironment may support escape from treatment. Using three-dimensional fluorescence imaging of t
Externí odkaz:
https://doaj.org/article/92a284cf059b4741ba558a277a2f6d2a
Publikováno v:
Frontiers in Oncology, Vol 8 (2018)
The bone marrow is the home of hematopoiesis and is therefore a hotspot for the development of hematopoietic diseases. Complex interactions between the bone marrow microenvironment and hematopoietic stem cells must find a balance between proliferatio
Externí odkaz:
https://doaj.org/article/96caab90eaed41088cff41b8aea34e81
Autor:
Karthiga Santhana Kumar, Anuja Neve, Ana S. Guerreiro Stucklin, Claudia M. Kuzan-Fischer, Elisabeth J. Rushing, Michael D. Taylor, Dimitra Tripolitsioti, Lena Behrmann, Daniel Kirschenbaum, Michael A. Grotzer, Martin Baumgartner
Publikováno v:
Cell Reports, Vol 23, Iss 13, Pp 3798-3812.e8 (2018)
Summary: The microenvironment shapes cell behavior and determines metastatic outcomes of tumors. We addressed how microenvironmental cues control tumor cell invasion in pediatric medulloblastoma (MB). We show that bFGF promotes MB tumor cell invasion
Externí odkaz:
https://doaj.org/article/ad1dfc8404584a9ca70dfeba989e2baf
Autor:
Veronika Lysenko, Donal McHugh, Lena Behrmann, Mary-Aude Rochat, Christian M. Wilk, Larisa Kovtonyuk, Jean-Pierre Bourquin, Christian Münz, Markus G. Manz, Roberto Speck, Alexandre P.A. Theocharides
Publikováno v:
Swiss Medical Weekly, Vol 147, Iss 4142 (2017)
“Humanised” mouse models have emerged over past years as powerful tools for investigating human haematopoiesis and immunity. They allowed the identification of key factors for the maintenance and function of normal and leukaemic human haematopoie
Externí odkaz:
https://doaj.org/article/048e3235ab2d4f718f460f7898cb3bcd
Autor:
Lena Behrmann, Scott McComb, Júlia Aguadé-Gorgorió, Yun Huang, Mario Hermann, Pawel Pelczar, Adriano Aguzzi, Jean Bourquin, Beat Bornhauser
Publikováno v:
Bio-Protocol, Vol 7, Iss 7 (2017)
CRISPR-Cas9 based knockout strategies are increasingly used to analyze gene function. However, redundancies and overlapping functions in biological signaling pathways can call for generating multi-gene knockout cells, which remains a relatively labor
Externí odkaz:
https://doaj.org/article/1b47fe1a935c45e28f8717171c989e5f
Autor:
Malwine J. Barz, Lena Behrmann, Danaëlle Capron, Gabriele Zuchtriegel, Fabio D. Steffen, Leo Kunz, Yang Zhang, Iria Jimenez Vermeerbergen, Blerim Marovca, Moritz Kirschmann, Antonia Zech, César Nombela-Arrieta, Urs Ziegler, Timm Schroeder, Beat Bornhauser, Jean-Pierre Bourquin
Publikováno v:
Haematologica, 108 (5)
Persistence of residual disease after induction chemotherapy is a strong predictor of relapse in acute lymphoblastic leukemia (ALL). The bone marrow microenvironment may support escape from treatment. Using three-dimensional fluorescence imaging of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bb4965a9ce5d1619bb216022bfcd419
Publikováno v:
Expert Opinion on Therapeutic Targets. 24:451-462
Introduction: Myeloid malignancies are caused by uncontrolled proliferation of neoplastic cells and lack of mature hematopoietic cells. Beside intrinsic genetic and epigenetic alterations within the neoplastic population, abnormal function of the bon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f99cf6787e4fb09803a31feaa2b40e6
https://doi.org/10.1080/14728222.2020.1744850
https://doi.org/10.1080/14728222.2020.1744850
Autor:
Jana Muschhammer, Lena Behrmann, Walter Fiedler, Franziska Brauneck, Eric Campeau, Franziska Modemann, Carsten Bokemeyer, Kais Khoury, Jasmin Wellbrock
Publikováno v:
Annals of Hematology
Modern cancer therapies increased the survival rates of acute myeloid leukemia (AML) patients tremendously. However, the complexity of the disease and the identification of new targets require the adaptation of treatment protocols to reduce side effe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5031ff37d4dd0c1881fe3fca4bdd9fd
https://pubmed.ncbi.nlm.nih.gov/34333666
https://pubmed.ncbi.nlm.nih.gov/34333666
Autor:
Jasmin Wellbrock, Fabian Freisleben, Vanessa Thaden, Walter Fiedler, Jana Muschhammer, Carsten Bokemeyer, Lena Behrmann
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 5084, p 5084 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 14
International Journal of Molecular Sciences
Volume 21
Issue 14
Aberrant activation of the hedgehog (HH) pathway is observed in many neoplasms, including acute myeloid leukemia (AML). The glioma-associated oncogene homolog (GLI) transcription factors are the main downstream effectors of the HH signaling cascade a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f46af50016ad930e6aac2c30b94d4fc6
https://www.mdpi.com/1422-0067/21/14/5084
https://www.mdpi.com/1422-0067/21/14/5084
Publikováno v:
Frontiers in Oncology, Vol 8 (2018)
Frontiers in Oncology
Frontiers in Oncology
The bone marrow is the home of hematopoiesis and is therefore a hotspot for the development of hematopoietic diseases. Complex interactions between the bone marrow microenvironment and hematopoietic stem cells must find a balance between proliferatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::377d7ba2779ea9a8777fc4e4a7c429d7
https://www.frontiersin.org/article/10.3389/fonc.2018.00444/full
https://www.frontiersin.org/article/10.3389/fonc.2018.00444/full