Zobrazeno 1 - 10
of 205
pro vyhledávání: '"Lena Öhman"'
Autor:
Samira Salihovic, Niklas Nyström, Charlotte Bache-Wiig Mathisen, Robert Kruse, Christine Olbjørn, Svend Andersen, Alexandra J. Noble, Maria Dorn-Rasmussen, Igor Bazov, Gøri Perminow, Randi Opheim, Trond Espen Detlie, Gert Huppertz-Hauss, Charlotte R. H. Hedin, Marie Carlson, Lena Öhman, Maria K. Magnusson, Åsa V. Keita, Johan D. Söderholm, Mauro D’Amato, Matej Orešič, Vibeke Wewer, Jack Satsangi, Carl Mårten Lindqvist, Johan Burisch, Holm H. Uhlig, Dirk Repsilber, Tuulia Hyötyläinen, Marte Lie Høivik, Jonas Halfvarson
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Improved biomarkers are needed for pediatric inflammatory bowel disease. Here we identify a diagnostic lipidomic signature for pediatric inflammatory bowel disease by analyzing blood samples from a discovery cohort of incident treatment-naï
Externí odkaz:
https://doaj.org/article/8a477108fc6e4a34a2cccb17d607374e
Autor:
Maria K. Magnusson, Anna Bas Forsberg, Alexandra Verveda, Maria Sapnara, Julie Lorent, Otto Savolainen, Yvonne Wettergren, Hans Strid, Magnus Simrén, Lena Öhman
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 18, p 9886 (2024)
Microbiota and luminal components may affect epithelial integrity and thus participate in the pathophysiology of colon cancer (CC) and inflammatory bowel disease (IBD). Therefore, we aimed to determine the effects of fecal luminal factors derived fro
Externí odkaz:
https://doaj.org/article/be778374bd1142b0a97e16ddcd6b73e9
Autor:
Frida Gorreja, Mia Bendix, Stephen T. A. Rush, Lujain Maasfeh, Otto Savolainen, Anders Dige, Jorgen Agnholt, Lena Öhman, Maria K. Magnusson
Publikováno v:
Cells, Vol 13, Iss 1, p 60 (2023)
Intestinal macrophages and fibroblasts act as microenvironmental sentinels mediating inflammation and disease progression in Crohn’s disease (CD). We aimed to establish the effects of fecal supernatants (FSs) from patients with CD on macrophage and
Externí odkaz:
https://doaj.org/article/e621b314c63240b4b7241ae70d60f38b
Autor:
Lena Öhman, Anders Lasson, Anna Strömbeck, Stefan Isaksson, Marcus Hesselmar, Magnus Simrén, Hans Strid, Maria K. Magnusson
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract Patients with ulcerative colitis (UC) have an altered gut microbiota composition, but the microbial relationship to disease activity needs to be further elucidated. Therefore, temporal dynamics of the fecal microbial community during remissi
Externí odkaz:
https://doaj.org/article/888e6863e5fa45338bf1f85f53a2768b
Autor:
Julien Tap, Stine Störsrud, Boris Le Nevé, Aurélie Cotillard, Nicolas Pons, Joël Doré, Lena Öhman, Hans Törnblom, Muriel Derrien, Magnus Simrén
Publikováno v:
Microbiome, Vol 9, Iss 1, Pp 1-13 (2021)
Abstract Background While several studies have documented associations between dietary habits and microbiota composition and function in healthy individuals, no study explored these associations in patients with irritable bowel syndrome (IBS), and es
Externí odkaz:
https://doaj.org/article/3644c9c1c608407b9034846adf041168
Autor:
Annikka Polster, Lena Öhman, Julien Tap, Muriel Derrien, Boris Le Nevé, Johanna Sundin, Hans Törnblom, Marija Cvijovic, Magnus Simrén
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Although incompletely understood, microbiota-host interactions are assumed to be altered in irritable bowel syndrome (IBS). We, therefore, aimed to develop a novel analysis pipeline tailored for the integrative analysis of microbiota-host in
Externí odkaz:
https://doaj.org/article/06b022d47b4b4e6d98e7d0e4754ed30b
Autor:
Lujain Maasfeh, Anetta Härtlova, Stefan Isaksson, Johanna Sundin, Georgios Mavroudis, Otto Savolainen, Hans Strid, Lena Öhman, Maria K. Magnusson
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 4, Pp 1415-1432 (2021)
Background & Aims: Intestinal macrophages adopt a hyporesponsive phenotype through education by local signals. Lack of proper macrophage maturation in patients with ulcerative colitis (UC) in remission may initiate gut inflammation. The aim, therefor
Externí odkaz:
https://doaj.org/article/cb556344adb14d9b9261e46d9bcea45c
Publikováno v:
Therapeutic Advances in Gastroenterology, Vol 15 (2022)
Introduction: Ulcerative colitis (UC) contributes to impaired health-related quality of life (HRQoL). Although disease activity is the most important factor, reduced HRQoL has been reported even in quiescent UC. We aimed to determine HRQoL, and ident
Externí odkaz:
https://doaj.org/article/ba19e655b6c0455aa075cc436808836e
Autor:
Anna Strömbeck, Anders Lasson, Hans Strid, Johanna Sundin, Per-Ove Stotzer, Magnus Simrén, Maria K. Magnusson, Lena Öhman
Publikováno v:
BMC Gastroenterology, Vol 20, Iss 1, Pp 1-10 (2020)
Abstract Background The role of the fecal microbiota composition for the postoperative disease course of patients with Crohn’s disease (CD) who have undergone ileocecal resection remains to be established. In this study, we investigated if the feca
Externí odkaz:
https://doaj.org/article/a6cdc09f169c47f8a3f251fc72ebbce0
Publikováno v:
Gut Microbiome, Vol 3 (2022)
Irritable bowel syndrome (IBS) is a disorder of gut–brain interaction with a complex pathophysiology. Growing evidence suggests that alterations of the gut microenvironment, including microbiota composition and function, may be involved in symptom
Externí odkaz:
https://doaj.org/article/5b7e918b1a9f4e1cb924c706e340b8b8