Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Lena, Lau"'
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Despite advancements in understanding cancer pathogenesis and the development of many effective therapeutic agents, resistance to drug treatment remains a widespread challenge that substantially limits curative outcomes. The historical focus on genet
Externí odkaz:
https://doaj.org/article/8371b0dfbd894045b742fef485f3f5bc
Publikováno v:
Oncogene
The acquisition of novel detrimental cellular properties following exposure to cytotoxic drugs leads to aggressive and metastatic tumors that often translates into an incurable disease. While the bulk of the primary tumor is eliminated upon exposure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19e6c6d3ed8866932246c4a967480c51
https://europepmc.org/articles/PMC9482949/
https://europepmc.org/articles/PMC9482949/
The acquisition of novel detrimental cellular properties following exposure to cytotoxic drugs leads to aggressive and metastatic tumors that often translates into an incurable disease. While the bulk of the primary tumor is eliminated upon exposure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::822d477f66db04b31d3156bbdce16755
https://doi.org/10.1101/2022.03.08.483463
https://doi.org/10.1101/2022.03.08.483463
Autor:
Shuai Wu, Katherine M. Aird, Joseph A. Zundell, David W. Speicher, Takeshi Fukumoto, David C. Schultz, Ken-ichi Noma, Zachary T. Schug, Osamu Iwasaki, Lena Lau, Rugang Zhang, Timothy Nacarelli, Nail Fatkhutdinov, Hsin Yao Tang, Joseph A. Baur, Andrew V. Kossenkov, Gregory David
Publikováno v:
Nature Cell Biology. 21:397-407
Cellular senescence is a stable growth arrest that is implicated in tissue ageing and cancer. Senescent cells are characterized by an upregulation of proinflammatory cytokines, which is termed the senescence-associated secretory phenotype (SASP). NAD
Autor:
Gregory David, Lena Lau
Publikováno v:
Expert Opin Ther Targets
INTRODUCTION: Cellular senescence is a stable form of cell-cycle exit. Though they no longer divide, senescent cells remain metabolically active and secrete a plethora of proteins collectively termed the senescence-associated secretory phenotype (SAS
Publikováno v:
Molecular and cellular biology. 39(12)
Cellular senescence has emerged as a potent tumor suppressor mechanism in numerous human neoplasias. Senescent cells secrete a distinct set of factors, collectively termed the senescence-associated secretory phenotype (SASP), which has been postulate
Autor:
Timothy, Nacarelli, Lena, Lau, Takeshi, Fukumoto, Joseph, Zundell, Nail, Fatkhutdinov, Shuai, Wu, Katherine M, Aird, Osamu, Iwasaki, Andrew V, Kossenkov, David, Schultz, Ken-Ichi, Noma, Joseph A, Baur, Zachary, Schug, Hsin-Yao, Tang, David W, Speicher, Gregory, David, Rugang, Zhang
Publikováno v:
Nature cell biology
Cellular senescence is a stable growth arrest that is implicated in tissue ageing and cancer. Senescent cells are characterized by an upregulation of proinflammatory cytokines, which is termed the senescence-associated secretory phenotype (SASP). NAD
Autor:
Lena, Lau, Gregory, David
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1534
Cellular senescence is defined as a state of stable cell-cycle arrest that is distinct from quiescence and terminal differentiation. Many stimuli can induce senescence, including telomere shortening and oncogene activation. The phenotypes elicited by
Autor:
Gregory David, Lena Lau
Publikováno v:
Methods in Molecular Biology ISBN: 9781493966684
Cellular senescence is defined as a state of stable cell-cycle arrest that is distinct from quiescence and terminal differentiation. Many stimuli can induce senescence, including telomere shortening and oncogene activation. The phenotypes elicited by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82a7c3e10d11b6376e7365ad201af295
https://doi.org/10.1007/978-1-4939-6670-7_2
https://doi.org/10.1007/978-1-4939-6670-7_2