Human anergic/suppressive CD4+CD25+ T cells: a highly differentiated and apoptosis-prone population

Autor: Leonie S. Taams, Arne N. Akbar, Mike Salmon, Jay Smith, Malcolm H.A. Rustin, Len W. Poulter

Publikováno v: European Journal of Immunology. 31:1122-1131

Anergic/suppressive CD4+CD25+ T cells exist in animal models but their presence has not yet been demonstrated in humans. We have identified and characterized a human CD4+CD25+ T cell subset, which constitutes 7–10 % of CD4+ T cells in peripheral bl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dd54f06f292c424f320153fb119649d9
https://doi.org/10.1002/1521-4141(200104)31:4<1122::aid-immu1122>3.0.co

1–14 Prélude: Macrophages in Inflammation / 15–35 Macrophages in Anti-Inflammation: Molecular Mechanisms / 36–46 Macrophages in Anti-Inflammation: Apoptosis / 47–56 Macrophages in Anti-Inflammation: Induction of Tolerance

Autor: F. Henry, Nahid Hakiy, F. Petersen, Edgar Dippel, Claus Kerkhoff, Gert Riethmüller, Kerstin Wolk, Claus-Detlev Klemke, Claudia Poppe, D.-H. Kalden, Andrew J. Rees, Christine Schütt, Kai Schledzewski, Vitam Kodelja, Ines Eue, K. Meflah, Len W. Poulter, G. Schmitz, M. Kauer, M. Ritter, Knut Schäkel, Robert Birk, Lukas Perler, M. Bodzioch, Thomas W. Jungi, T.A. Hamilton, T. Brzoska, Bernard Uitdehaag, Volker von Baehr, W. Drobnik, B. Scheuerer, Leonie S. Taams, Birgit Klein, E. Grage-Griebenow, P'ng Loke, H. Horowitz, Li Li, H. Tabel, T. Orlikowsky, Robert Sabat, R.S. Kaushik, J. Uzonna, E. Orsó, S. Martin, E. Brandt, Hans-Dieter Volk, J. Pryjma, Manfred Kauer, B. Lieubeau, G.E. Dannecker, M. Ernst, Ernst Peterhans, T. Vogl, Abalokita Chakraborty, Sergij Goerdt, Anne Devine, Andrew S. MacDonald, Wayne P. Pearce, C. Büchler, M. Porsch-Özcürümez, Ernst Peter Rieber, I. Barbieux, J. Baran, Clemens Sorg, Jan W. Koper, K. Steinbrink, Arne N. Akbar, C. Buechler, Z.-Q. Wang, Nitya G. Chakraborty, W.E. Kaminski, R. Kishore, J.M. Tebo, Gabriele Zwadlo-Klarwasser, Miguel J. Stadecker, Constantin E. Orfanos, R. Stumpo, J. Klucken, Judith E. Allen, Wolf-Dietrich Döcke, E. Macher, Bijay Mukherji, Y. Ohmori, H.-D. Flad, M. Grégoire, M.K. Hoffmann, Ruth Schiffer, Malcolm H.A. Rustin, T.E. Scholzen, Bernd Klosterhalfen, Hubert Kolb, T. Langmann, Oliver Politz, C. Sorg, J. Pior, Jurgen Jansen, L. Bretaudeau, H. Kolb, Pierre Guillot, Yoong-Eun Kim, Lars-Peter Erwig, A. Hequet, Christine Federle, Timo K. van den Berg, Alexej Gratchev, Volker Burkart, Michael S. McGrath, T.A. Luger, Elfriede Mayer, Robert N. Barker, D. Niethammer, Matthias Schweizer

Publikováno v: Pathobiology. 67:322-340

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6ccffb421a2cc6fc74b4beeaacb98c53
https://doi.org/10.1159/000028090

Functionally relevant changes occur in HIV-infected individualsʼ alveolar macrophages prior to the onset of respiratory disease

Autor: Margaret A. Johnson, Marc Lipman, Len W. Poulter

Publikováno v: AIDS. 11:765-772

Objective: We have compared the phenotypic and functional changes found in alveolar macrophages recovered from the lungs of 39 HIV-positive individuals with no respiratory disease with those from 33 HIV-positive individuals with pneumonitis and 31 he

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::480eb9b31d05fdd1a05ec0a1e573c483
https://doi.org/10.1097/00002030-199706000-00010

The inhibition of cutaneous T cell apoptosis may prevent resolution of inflammation in atopic eczema

Autor: M.H.A. Rustin, C. H. Orteu, Mike Salmon, E. O'toole, Caroline A. Sabin, Len W. Poulter, Arne N. Akbar

Publikováno v: Clinical and experimental immunology. 122(2)

SUMMARYAtopic eczema (AE) is characterized by the persistence of infiltrating T lymphocytes in the dermis. To test the hypothesis that dysregulation of normal T cell apoptosis may contribute to the pathogenesis and chronicity of AE we compared patien

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29a586d8f54827962235f06ddfe67900
https://pubmed.ncbi.nlm.nih.gov/11091268

Immunology of infection edited by H.E. Kaufmann and D. Kabelitz

Autor: Len W Poulter

Publikováno v: Immunology Today. 20:385

Academic Press, 1998. $59.95 (xiv+705 pages)ISBN 0 12 402305 3This volume represents number 25 in the series Methods in Microbiology. It is a multiauthor book that includes contributions from a worldwide selection of experts in microbiology and immun

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f6b56442855436a0680f7810cd889e5d
https://doi.org/10.1016/s0167-5699(99)01487-5