NKG2D promotes CD8 memory T cell formation by modulating PI3K signaling and enhancing survival of memory precursors

Autor: Wensveen, Felix Martinus, Gulin, Maja, Jelenčić, Vedrana, Lemmermann, NAW, Ten Brinke, Anja, Jonjić, Stipan, Colonna, M, Polić, Bojan

Memory T cell formationa is the result of an intricate balance between extracellular cues and intracellular signaling components. NKG2D (coded by Klrk1) is an activating receptor which potentiates cytotoxic cell function by stimulating PI3K pathway.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::b666ce34f0cf718980cbe418b8dd96cb
https://www.bib.irb.hr/680826

Rapid protection against viral infections by chemokine-accelerated post-exposure vaccination.

Autor: Heine A; Institute of Experimental Immunology, University of Bonn, Bonn, Germany.; Medical Clinic III, University of Bonn, Bonn, Germany., Lemmermann NAW; Institute for Virology and Research Center for Immunotherapy (FZI) at the University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.; Institute for Virology, University of Bonn, Bonn, Germany., Flores C; Institute of Experimental Immunology, University of Bonn, Bonn, Germany.; Medical Clinic III, University of Bonn, Bonn, Germany., Becker-Gotot J; Institute of Experimental Immunology, University of Bonn, Bonn, Germany., Garbi N; Institute of Experimental Immunology, University of Bonn, Bonn, Germany., Brossart P; Medical Clinic III, University of Bonn, Bonn, Germany., Kurts C; Institute of Experimental Immunology, University of Bonn, Bonn, Germany.; Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, VIC, Australia.

Publikováno v: Frontiers in immunology [Front Immunol] 2024 Jan 29; Vol. 15, pp. 1338499. Date of Electronic Publication: 2024 Jan 29 (Print Publication: 2024).

Therapeutic Vaccination of Hematopoietic Cell Transplantation Recipients Improves Protective CD8 T-Cell Immunotherapy of Cytomegalovirus Infection.

Autor: Gergely KM; Institute for Virology and Research Center for Immunotherapy (FZI) at the University Medical Center of the Johannes Gutenberg-University of Mainz, Mainz, Germany., Podlech J; Institute for Virology and Research Center for Immunotherapy (FZI) at the University Medical Center of the Johannes Gutenberg-University of Mainz, Mainz, Germany., Becker S; Institute for Virology and Research Center for Immunotherapy (FZI) at the University Medical Center of the Johannes Gutenberg-University of Mainz, Mainz, Germany., Freitag K; Institute for Virology and Research Center for Immunotherapy (FZI) at the University Medical Center of the Johannes Gutenberg-University of Mainz, Mainz, Germany., Krauter S; Institute for Virology and Research Center for Immunotherapy (FZI) at the University Medical Center of the Johannes Gutenberg-University of Mainz, Mainz, Germany., Büscher N; Institute for Virology and Research Center for Immunotherapy (FZI) at the University Medical Center of the Johannes Gutenberg-University of Mainz, Mainz, Germany., Holtappels R; Institute for Virology and Research Center for Immunotherapy (FZI) at the University Medical Center of the Johannes Gutenberg-University of Mainz, Mainz, Germany., Plachter B; Institute for Virology and Research Center for Immunotherapy (FZI) at the University Medical Center of the Johannes Gutenberg-University of Mainz, Mainz, Germany., Reddehase MJ; Institute for Virology and Research Center for Immunotherapy (FZI) at the University Medical Center of the Johannes Gutenberg-University of Mainz, Mainz, Germany., Lemmermann NAW; Institute for Virology and Research Center for Immunotherapy (FZI) at the University Medical Center of the Johannes Gutenberg-University of Mainz, Mainz, Germany.

Publikováno v: Frontiers in immunology [Front Immunol] 2021 Aug 19; Vol. 12, pp. 694588. Date of Electronic Publication: 2021 Aug 19 (Print Publication: 2021).

Direct Evidence for Viral Antigen Presentation during Latent Cytomegalovirus Infection.

Autor: Lemmermann NAW; Institute for Virology and Research Center for Immunotherapy (FZI), University Medical Center of the Johannes Gutenberg-University Mainz, 55131 Mainz, Germany., Reddehase MJ; Institute for Virology and Research Center for Immunotherapy (FZI), University Medical Center of the Johannes Gutenberg-University Mainz, 55131 Mainz, Germany.

Publikováno v: Pathogens (Basel, Switzerland) [Pathogens] 2021 Jun 10; Vol. 10 (6). Date of Electronic Publication: 2021 Jun 10.

No Evidence for Classic Thrombotic Microangiopathy in COVID-19.

Autor: Falter T; Institute of Clinical Chemistry and Laboratory medicine, University Medical Center of the Johannes Gutenberg University Mainz, 55131 Mainz, Germany., Rossmann H; Institute of Clinical Chemistry and Laboratory medicine, University Medical Center of the Johannes Gutenberg University Mainz, 55131 Mainz, Germany., Menge P; Medical Department I, University Medical Center of the Johannes Gutenberg University Mainz, 55131 Mainz, Germany., Goetje J; Medical Department I, University Medical Center of the Johannes Gutenberg University Mainz, 55131 Mainz, Germany., Groenwoldt S; Medical Department I, University Medical Center of the Johannes Gutenberg University Mainz, 55131 Mainz, Germany., Weinmann A; Medical Department I, University Medical Center of the Johannes Gutenberg University Mainz, 55131 Mainz, Germany.; Clinical Registry Unit, University Medical Center of the Johannes Gutenberg University Mainz, 55131 Mainz, Germany., Sivanathan V; Medical Department I, University Medical Center of the Johannes Gutenberg University Mainz, 55131 Mainz, Germany., Schulz A; Center for Thrombosis and Hemostasis, University Medical Center of the Johannes Gutenberg University Mainz, 55131 Mainz, Germany., Lemmermann NAW; Institute of Virology, University Medical Center of the Johannes Gutenberg University Mainz, 55131 Mainz, Germany., Danckwardt S; Institute of Clinical Chemistry and Laboratory medicine, University Medical Center of the Johannes Gutenberg University Mainz, 55131 Mainz, Germany.; Center for Thrombosis and Hemostasis, University Medical Center of the Johannes Gutenberg University Mainz, 55131 Mainz, Germany., Lackner KJ; Institute of Clinical Chemistry and Laboratory medicine, University Medical Center of the Johannes Gutenberg University Mainz, 55131 Mainz, Germany., Galle PR; Medical Department I, University Medical Center of the Johannes Gutenberg University Mainz, 55131 Mainz, Germany., Scharrer I; Center for Thrombosis and Hemostasis, University Medical Center of the Johannes Gutenberg University Mainz, 55131 Mainz, Germany., Lämmle B; Center for Thrombosis and Hemostasis, University Medical Center of the Johannes Gutenberg University Mainz, 55131 Mainz, Germany.; Department of Hematology and Central Hematology Laboratory, Inselspital, Bern University Hospital, University of Bern, CH 3010 Bern, Switzerland.; Haemostasis Research Unit, University College London, London WC1E 6BT, UK., Sprinzl MF; Institute of Clinical Chemistry and Laboratory medicine, University Medical Center of the Johannes Gutenberg University Mainz, 55131 Mainz, Germany.; Medical Department I, University Medical Center of the Johannes Gutenberg University Mainz, 55131 Mainz, Germany.; Clinical Registry Unit, University Medical Center of the Johannes Gutenberg University Mainz, 55131 Mainz, Germany.

Publikováno v: Journal of clinical medicine [J Clin Med] 2021 Feb 09; Vol. 10 (4). Date of Electronic Publication: 2021 Feb 09.