Cytomegalovirus inhibitors of programmed cell death restrict antigen cross-presentation in the priming of antiviral CD8 T cells.

Autor: Ebert S; Institute for Virology, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany., Böhm V; Institute for Virology, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany., Büttner JK; Institute for Virology, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany., Brune W; Leibniz Institute of Virology (LIV), Hamburg, Germany., Brinkmann MM; Institute of Genetics, Technische Universität Braunschweig, Braunschweig, Germany.; Virology and Innate Immunity Research Group, Helmholtz Centre for Infection Research, Braunschweig, Germany., Holtappels R; Institute for Virology, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.; Research Center for Immunotherapy (FZI), University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany., Reddehase MJ; Institute for Virology, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.; Research Center for Immunotherapy (FZI), University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany., Lemmermann NAW; Institute for Virology, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.; Research Center for Immunotherapy (FZI), University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.; Institute of Virology, Medical Faculty, University of Bonn, Bonn, Germany.

Publikováno v: PLoS pathogens [PLoS Pathog] 2024 Aug 15; Vol. 20 (8), pp. e1012173. Date of Electronic Publication: 2024 Aug 15 (Print Publication: 2024).

Efficient Delivery of Human Cytomegalovirus T Cell Antigens by Attenuated Sendai Virus Vectors

Autor: Christine Kaufmann, Lemmermann Naw, Richard Kiener, Ralf Wagner, Marian Wiegand, Schwegler C, Angélique Renzaho, Benedikt Asbach, Felder E, Fleischmann M, Hans-Helmut Niller, Simone Thomas

Publikováno v: Journal of virology. 92(15)

Human cytomegalovirus (HCMV) represents a major cause of clinical complications during pregnancy as well as immunosuppression, and the licensing of a protective HCMV vaccine remains an unmet global need. Here, we designed and validated novel Sendai v

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6908cb42b06a1a50466a1c0162f07ee
https://pubmed.ncbi.nlm.nih.gov/29769344

Therapeutic Vaccination of Hematopoietic Cell Transplantation Recipients Improves Protective CD8 T-Cell Immunotherapy of Cytomegalovirus Infection.

Autor: Gergely KM; Institute for Virology and Research Center for Immunotherapy (FZI) at the University Medical Center of the Johannes Gutenberg-University of Mainz, Mainz, Germany., Podlech J; Institute for Virology and Research Center for Immunotherapy (FZI) at the University Medical Center of the Johannes Gutenberg-University of Mainz, Mainz, Germany., Becker S; Institute for Virology and Research Center for Immunotherapy (FZI) at the University Medical Center of the Johannes Gutenberg-University of Mainz, Mainz, Germany., Freitag K; Institute for Virology and Research Center for Immunotherapy (FZI) at the University Medical Center of the Johannes Gutenberg-University of Mainz, Mainz, Germany., Krauter S; Institute for Virology and Research Center for Immunotherapy (FZI) at the University Medical Center of the Johannes Gutenberg-University of Mainz, Mainz, Germany., Büscher N; Institute for Virology and Research Center for Immunotherapy (FZI) at the University Medical Center of the Johannes Gutenberg-University of Mainz, Mainz, Germany., Holtappels R; Institute for Virology and Research Center for Immunotherapy (FZI) at the University Medical Center of the Johannes Gutenberg-University of Mainz, Mainz, Germany., Plachter B; Institute for Virology and Research Center for Immunotherapy (FZI) at the University Medical Center of the Johannes Gutenberg-University of Mainz, Mainz, Germany., Reddehase MJ; Institute for Virology and Research Center for Immunotherapy (FZI) at the University Medical Center of the Johannes Gutenberg-University of Mainz, Mainz, Germany., Lemmermann NAW; Institute for Virology and Research Center for Immunotherapy (FZI) at the University Medical Center of the Johannes Gutenberg-University of Mainz, Mainz, Germany.

Publikováno v: Frontiers in immunology [Front Immunol] 2021 Aug 19; Vol. 12, pp. 694588. Date of Electronic Publication: 2021 Aug 19 (Print Publication: 2021).

Direct Evidence for Viral Antigen Presentation during Latent Cytomegalovirus Infection.

Autor: Lemmermann NAW; Institute for Virology and Research Center for Immunotherapy (FZI), University Medical Center of the Johannes Gutenberg-University Mainz, 55131 Mainz, Germany., Reddehase MJ; Institute for Virology and Research Center for Immunotherapy (FZI), University Medical Center of the Johannes Gutenberg-University Mainz, 55131 Mainz, Germany.

Publikováno v: Pathogens (Basel, Switzerland) [Pathogens] 2021 Jun 10; Vol. 10 (6). Date of Electronic Publication: 2021 Jun 10.

No Evidence for Classic Thrombotic Microangiopathy in COVID-19.

Autor: Falter T; Institute of Clinical Chemistry and Laboratory medicine, University Medical Center of the Johannes Gutenberg University Mainz, 55131 Mainz, Germany., Rossmann H; Institute of Clinical Chemistry and Laboratory medicine, University Medical Center of the Johannes Gutenberg University Mainz, 55131 Mainz, Germany., Menge P; Medical Department I, University Medical Center of the Johannes Gutenberg University Mainz, 55131 Mainz, Germany., Goetje J; Medical Department I, University Medical Center of the Johannes Gutenberg University Mainz, 55131 Mainz, Germany., Groenwoldt S; Medical Department I, University Medical Center of the Johannes Gutenberg University Mainz, 55131 Mainz, Germany., Weinmann A; Medical Department I, University Medical Center of the Johannes Gutenberg University Mainz, 55131 Mainz, Germany.; Clinical Registry Unit, University Medical Center of the Johannes Gutenberg University Mainz, 55131 Mainz, Germany., Sivanathan V; Medical Department I, University Medical Center of the Johannes Gutenberg University Mainz, 55131 Mainz, Germany., Schulz A; Center for Thrombosis and Hemostasis, University Medical Center of the Johannes Gutenberg University Mainz, 55131 Mainz, Germany., Lemmermann NAW; Institute of Virology, University Medical Center of the Johannes Gutenberg University Mainz, 55131 Mainz, Germany., Danckwardt S; Institute of Clinical Chemistry and Laboratory medicine, University Medical Center of the Johannes Gutenberg University Mainz, 55131 Mainz, Germany.; Center for Thrombosis and Hemostasis, University Medical Center of the Johannes Gutenberg University Mainz, 55131 Mainz, Germany., Lackner KJ; Institute of Clinical Chemistry and Laboratory medicine, University Medical Center of the Johannes Gutenberg University Mainz, 55131 Mainz, Germany., Galle PR; Medical Department I, University Medical Center of the Johannes Gutenberg University Mainz, 55131 Mainz, Germany., Scharrer I; Center for Thrombosis and Hemostasis, University Medical Center of the Johannes Gutenberg University Mainz, 55131 Mainz, Germany., Lämmle B; Center for Thrombosis and Hemostasis, University Medical Center of the Johannes Gutenberg University Mainz, 55131 Mainz, Germany.; Department of Hematology and Central Hematology Laboratory, Inselspital, Bern University Hospital, University of Bern, CH 3010 Bern, Switzerland.; Haemostasis Research Unit, University College London, London WC1E 6BT, UK., Sprinzl MF; Institute of Clinical Chemistry and Laboratory medicine, University Medical Center of the Johannes Gutenberg University Mainz, 55131 Mainz, Germany.; Medical Department I, University Medical Center of the Johannes Gutenberg University Mainz, 55131 Mainz, Germany.; Clinical Registry Unit, University Medical Center of the Johannes Gutenberg University Mainz, 55131 Mainz, Germany.

Publikováno v: Journal of clinical medicine [J Clin Med] 2021 Feb 09; Vol. 10 (4). Date of Electronic Publication: 2021 Feb 09.