Membrane remodelling triggers maturation of excitation–contraction coupling in 3D-shaped human-induced pluripotent stem cell-derived cardiomyocytes.

Autor: Kermani, Fatemeh, Mosqueira, Matias, Peters, Kyra, Lemma, Enrico D., Rapti, Kleopatra, Grimm, Dirk, Bastmeyer, Martin, Laugsch, Magdalena, Hecker, Markus, Ullrich, Nina D.

Publikováno v: Basic Research in Cardiology; Dec2023, Vol. 118 Issue 1, p1-16, 16p

Mechanical stimulation of single cells by reversible host-guest interactions in 3D microscaffolds

Autor: Hippler, Marc, Weißenbruch, Kai, Richler, Kai, Lemma, Enrico D., Nakahata, Masaki, Richter, Benjamin, Barner-Kowollik, Christopher, Takashima, Yoshinori, Harada, Akira, Blasco, Eva, Wegener, Martin, Tanaka, Motomu, Bastmeyer, Martin

Publikováno v: Science advances, 6 (39), Art. Nr.: eabc2648
Science Advances

Using stimuli-responsive hydrogels, we 3D print composite microscaffolds to analyze mechanobiology on the single-cell level.
Many essential cellular processes are regulated by mechanical properties of their microenvironment. Here, we introduce s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e2a27875e547f91e6d22707cd02bb8c
https://publikationen.bibliothek.kit.edu/1000125343

Mechanical stimulation of single cells by reversible host-guest interactions in 3D microscaffolds.

Autor: Hippler M; Institute of Applied Physics, Karlsruhe Institute of Technology (KIT), 76128 Karlsruhe, Germany. marc.hippler@kit.edu martin.wegener@kit.edu tanaka@uni-heidelberg.de martin.bastmeyer@kit.edu.; Zoological Institute, Karlsruhe Institute of Technology (KIT), 76128 Karlsruhe, Germany., Weißenbruch K; Zoological Institute, Karlsruhe Institute of Technology (KIT), 76128 Karlsruhe, Germany.; Institute of Functional Interfaces, Karlsruhe Institute of Technology (KIT), 76128 Karlsruhe, Germany., Richler K; Zoological Institute, Karlsruhe Institute of Technology (KIT), 76128 Karlsruhe, Germany., Lemma ED; Zoological Institute, Karlsruhe Institute of Technology (KIT), 76128 Karlsruhe, Germany., Nakahata M; Department of Materials Engineering Science, Graduate School of Engineering Science, Osaka University, Toyonaka, Osaka 560-8531, Japan., Richter B; Zoological Institute, Karlsruhe Institute of Technology (KIT), 76128 Karlsruhe, Germany., Barner-Kowollik C; Centre for Materials Science, Queensland University of Technology (QUT), 2 George Street, Brisbane, QLD 4000, Australia.; School of Chemistry and Physics, Queensland University of Technology (QUT), 2 George Street, Brisbane, QLD 4000, Australia.; Institute of Nanotechnology, Karlsruhe Institute of Technology (KIT), 76128 Karlsruhe, Germany., Takashima Y; Department of Macromolecular Science, Graduate School of Science, Osaka University, 1-1 Machikaneyama-cho, Toyonaka, Osaka 560-0043, Japan., Harada A; Department of Macromolecular Science, Graduate School of Science, Osaka University, 1-1 Machikaneyama-cho, Toyonaka, Osaka 560-0043, Japan., Blasco E; Institute of Nanotechnology, Karlsruhe Institute of Technology (KIT), 76128 Karlsruhe, Germany.; Institute for Chemical Technology and Polymer Chemistry, Karlsruhe Institute of Technology (KIT), 76128 Karlsruhe, Germany., Wegener M; Institute of Applied Physics, Karlsruhe Institute of Technology (KIT), 76128 Karlsruhe, Germany. marc.hippler@kit.edu martin.wegener@kit.edu tanaka@uni-heidelberg.de martin.bastmeyer@kit.edu.; Institute for Chemical Technology and Polymer Chemistry, Karlsruhe Institute of Technology (KIT), 76128 Karlsruhe, Germany., Tanaka M; Institute of Physical Chemistry, Heidelberg University, Im Neuenheimer Feld 253, 69120 Heidelberg, Germany. marc.hippler@kit.edu martin.wegener@kit.edu tanaka@uni-heidelberg.de martin.bastmeyer@kit.edu.; Center for Integrative Medicine and Physics, Institute for Advanced Study, Kyoto University, Kyoto 606-8501, Japan., Bastmeyer M; Zoological Institute, Karlsruhe Institute of Technology (KIT), 76128 Karlsruhe, Germany. marc.hippler@kit.edu martin.wegener@kit.edu tanaka@uni-heidelberg.de martin.bastmeyer@kit.edu.; Institute of Functional Interfaces, Karlsruhe Institute of Technology (KIT), 76128 Karlsruhe, Germany.

Publikováno v: Science advances [Sci Adv] 2020 Sep 23; Vol. 6 (39). Date of Electronic Publication: 2020 Sep 23 (Print Publication: 2020).