Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Lemke CT"'
Akademický článek
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K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Kwon JJ; Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA, 02115, USA.; Harvard Medical School, Boston, MA, 02115, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA., Dilly J; Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA, 02115, USA.; Harvard Medical School, Boston, MA, 02115, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA., Liu S; Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA, 02115, USA.; Harvard Medical School, Boston, MA, 02115, USA., Kim E; Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA, 02115, USA.; Harvard Medical School, Boston, MA, 02115, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA., Bian Y; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA., Dharmaiah S; NCI RAS Initiative, Cancer Research Technology Program, Frederick National Laboratory for Cancer Research, Frederick, MD, USA., Tran TH; NCI RAS Initiative, Cancer Research Technology Program, Frederick National Laboratory for Cancer Research, Frederick, MD, USA., Kapner KS; Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA, 02115, USA.; Harvard Medical School, Boston, MA, 02115, USA., Ly SH; Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA, 02115, USA.; Harvard Medical School, Boston, MA, 02115, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA., Yang X; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA., Rabara D; NCI RAS Initiative, Cancer Research Technology Program, Frederick National Laboratory for Cancer Research, Frederick, MD, USA., Waybright TJ; NCI RAS Initiative, Cancer Research Technology Program, Frederick National Laboratory for Cancer Research, Frederick, MD, USA., Giacomelli AO; Humber Polytechnic, Toronto, ON, Canada., Hong AL; Department of Pediatrics, Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, GA, USA., Misek S; Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA, 02115, USA.; Harvard Medical School, Boston, MA, 02115, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA., Wang B; Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA, 02115, USA.; Harvard Medical School, Boston, MA, 02115, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA., Ravi A; Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA, 02115, USA.; Harvard Medical School, Boston, MA, 02115, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA., Doench JG; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA., Beroukhim R; Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA, 02115, USA.; Harvard Medical School, Boston, MA, 02115, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA., Lemke CT; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA., Haigis KM; Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA, 02115, USA.; Harvard Medical School, Boston, MA, 02115, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA., Esposito D; NCI RAS Initiative, Cancer Research Technology Program, Frederick National Laboratory for Cancer Research, Frederick, MD, USA., Root DE; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA., Nissley DV; NCI RAS Initiative, Cancer Research Technology Program, Frederick National Laboratory for Cancer Research, Frederick, MD, USA., Stephen AG; NCI RAS Initiative, Cancer Research Technology Program, Frederick National Laboratory for Cancer Research, Frederick, MD, USA., McCormick F; NCI RAS Initiative, Cancer Research Technology Program, Frederick National Laboratory for Cancer Research, Frederick, MD, USA.; University of California, San Francisco Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, CA, USA., Simanshu DK; NCI RAS Initiative, Cancer Research Technology Program, Frederick National Laboratory for Cancer Research, Frederick, MD, USA., Hahn WC; Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA, 02115, USA.; Harvard Medical School, Boston, MA, 02115, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA., Aguirre AJ; Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA, 02115, USA.; Harvard Medical School, Boston, MA, 02115, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.
Publikováno v:
BioRxiv : the preprint server for biology [bioRxiv] 2024 Oct 25. Date of Electronic Publication: 2024 Oct 25.
Autor:
Rauh U; Trueline Therapeutics Inc., Cambridge, MA, USA. ulla@truelinetx.com., Wei G; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Serrano-Wu M; Anji Pharmaceuticals Inc., Cambridge, MA, USA., Kosmidis G; Ncardia, Leiden, The Netherlands., Kaulfuss S; Nuvisan Innovation Campus Berlin, Berlin, Germany., Siegel F; Bayer AG R&D, Berlin, Germany., Thede K; Nuvisan Innovation Campus Berlin, Berlin, Germany., McFarland J; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Lemke CT; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Werbeck N; Bayer AG R&D, Berlin, Germany., Nowak-Reppel K; Nuvisan Innovation Campus Berlin, Berlin, Germany., Pilari S; Independent Consultant, Pharmacometrics Modeling and Simulation, Berlin, Germany., Menz S; Bayer AG R&D, Berlin, Germany., Ocker M; Trueline Therapeutics Inc., Cambridge, MA, USA., Zhang W; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Davis K; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Poncet-Montange G; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Roth J; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Daniels D; Trueline Therapeutics Inc., Cambridge, MA, USA., Kaushik VK; Trueline Therapeutics Inc., Cambridge, MA, USA., Hubbard B; Anji Pharmaceuticals Inc., Cambridge, MA, USA., Ziegelbauer K; Almirall R&D, Sant Feliu de Llobregat, Spain., Golub TR; Broad Institute of MIT and Harvard, Cambridge, MA, USA. golub@broadinstitute.org.; Department of Pediatric Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA, USA. golub@broadinstitute.org.
Publikováno v:
Nature cancer [Nat Cancer] 2024 Oct; Vol. 5 (10), pp. 1479-1493. Date of Electronic Publication: 2024 Aug 23.
Autor:
Rubinson DA; Dana Farber Cancer Institute and Department of Medicine, Harvard Medical School, Boston, Massachusetts., Tanaka N; Massachusetts General Hospital Cancer Center and Department of Medicine, Harvard Medical School, Boston, Massachusetts., Fece de la Cruz F; Massachusetts General Hospital Cancer Center and Department of Medicine, Harvard Medical School, Boston, Massachusetts., Kapner KS; Dana Farber Cancer Institute and Department of Medicine, Harvard Medical School, Boston, Massachusetts.; The Broad Institute of Harvard and MIT, Cambridge, Massachusetts., Rosenthal MH; Dana Farber Cancer Institute and Brigham and Women's Hospital, Department of Radiology, Boston, Massachusetts.; Harvard Medical School, Boston, Massachusetts., Norden BL; Massachusetts General Hospital Cancer Center and Department of Medicine, Harvard Medical School, Boston, Massachusetts., Barnes H; Massachusetts General Hospital Cancer Center and Department of Medicine, Harvard Medical School, Boston, Massachusetts., Ehnstrom S; Massachusetts General Hospital Cancer Center and Department of Medicine, Harvard Medical School, Boston, Massachusetts., Morales-Giron AA; Massachusetts General Hospital Cancer Center and Department of Medicine, Harvard Medical School, Boston, Massachusetts., Brais LK; Dana Farber Cancer Institute and Department of Medicine, Harvard Medical School, Boston, Massachusetts., Lemke CT; The Broad Institute of Harvard and MIT, Cambridge, Massachusetts., Aguirre AJ; Dana Farber Cancer Institute and Department of Medicine, Harvard Medical School, Boston, Massachusetts.; The Broad Institute of Harvard and MIT, Cambridge, Massachusetts., Corcoran RB; Massachusetts General Hospital Cancer Center and Department of Medicine, Harvard Medical School, Boston, Massachusetts.
Publikováno v:
Cancer discovery [Cancer Discov] 2024 May 01; Vol. 14 (5), pp. 727-736.
Autor:
Babbe H; Janssen Research and Development, LLC., Spring House, PA 19477., Sundberg TB; Broad Institute of MIT and Harvard, Center for the Development of Therapeutics, Cambridge, MA 02142., Tichenor M; Janssen Research and Development, LLC., San Diego, CA 92121., Seierstad M; Janssen Research and Development, LLC., San Diego, CA 92121., Bacani G; Janssen Research and Development, LLC., San Diego, CA 92121., Berstler J; Broad Institute of MIT and Harvard, Center for the Development of Therapeutics, Cambridge, MA 02142., Chai W; Janssen Research and Development, LLC., San Diego, CA 92121., Chang L; Janssen Research and Development, LLC., San Diego, CA 92121., Chung M; Janssen Research and Development, LLC., San Diego, CA 92121., Coe K; Janssen Research and Development, LLC., San Diego, CA 92121., Collins B; Janssen Research and Development, LLC., San Diego, CA 92121., Finley M; Janssen Research and Development, LLC., Spring House, PA 19477., Guletsky A; Broad Institute of MIT and Harvard, Center for the Development of Therapeutics, Cambridge, MA 02142., Lemke CT; Broad Institute of MIT and Harvard, Center for the Development of Therapeutics, Cambridge, MA 02142., Mak PA; Janssen Research and Development, LLC., San Diego, CA 92121., Mathur A; Janssen Research and Development, LLC., Spring House, PA 19477., Mercado-Marin EV; Janssen Research and Development, LLC., San Diego, CA 92121., Metkar S; Broad Institute of MIT and Harvard, Center for the Development of Therapeutics, Cambridge, MA 02142., Raymond DD; Broad Institute of MIT and Harvard, Center for the Development of Therapeutics, Cambridge, MA 02142., Rives ML; Janssen Research and Development, LLC., San Diego, CA 92121., Rizzolio M; Janssen Research and Development, LLC., San Diego, CA 92121., Shaffer PL; Janssen Research and Development, LLC., Spring House, PA 19477., Smith R; Janssen Research and Development, LLC., San Diego, CA 92121., Smith J; Janssen Research and Development, LLC., San Diego, CA 92121., Steele R; Janssen Research and Development, LLC., Spring House, PA 19477., Steffens H; Janssen Research and Development, LLC., San Diego, CA 92121., Suarez J; Janssen Research and Development, LLC., Spring House, PA 19477., Tian G; Janssen Research and Development, LLC., Spring House, PA 19477., Majewski N; Janssen Research and Development, LLC., Spring House, PA 19477., Volak LP; Janssen Research and Development, LLC., San Diego, CA 92121., Wei J; Janssen Research and Development, LLC., San Diego, CA 92121., Desai PT; Janssen Research and Development, LLC., Spring House, PA 19477., Ong LL; Janssen Research and Development, LLC., Spring House, PA 19477., Koudriakova T; Janssen Research and Development, LLC., San Diego, CA 92121., Goldberg SD; Janssen Research and Development, LLC., San Diego, CA 92121., Hirst G; Janssen Research and Development, LLC., San Diego, CA 92121., Kaushik VK; Broad Institute of MIT and Harvard, Center for the Development of Therapeutics, Cambridge, MA 02142., Ort T; Janssen Research and Development, LLC., Spring House, PA 19477., Seth N; Janssen Research and Development, LLC., Spring House, PA 19477., Graham DB; Center for Computational and Integrative Biology, Massachusetts General Hospital, Boston, MA 02114.; Department of Molecular Biology, Massachusetts General Hospital, Boston, MA 02114.; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA 02142., Plevy S; Janssen Research and Development, LLC., Spring House, PA 19477., Venable JD; Janssen Research and Development, LLC., San Diego, CA 92121., Xavier RJ; Center for Computational and Integrative Biology, Massachusetts General Hospital, Boston, MA 02114.; Department of Molecular Biology, Massachusetts General Hospital, Boston, MA 02114.; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA 02142., Towne JE; Janssen Research and Development, LLC., San Diego, CA 92121.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2024 Jan 02; Vol. 121 (1), pp. e2307086120. Date of Electronic Publication: 2023 Dec 26.
Autor:
Orsi DL; Center for the Development of Therapeutics, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Ferrara SJ; Center for the Development of Therapeutics, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Siegel S; Research and Development, Pharmaceuticals, Bayer AG, 13353 Berlin, Germany., Friberg A; Nuvisan ICB GmbH, 13353 Berlin, Germany., Bouché L; Research and Development, Pharmaceuticals, Bayer AG, 13353 Berlin, Germany., Pook E; Research and Development, Pharmaceuticals, Bayer AG, 42113 Wuppertal, Germany., Lienau P; Research and Development, Pharmaceuticals, Bayer AG, 13353 Berlin, Germany., Bluck JP; Research and Development, Pharmaceuticals, Bayer AG, 13353 Berlin, Germany., Lemke CT; Center for the Development of Therapeutics, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Akcay G; Bayer US LLC, Research and Development Precision Molecular Oncology, Cambridge, MA 02142, USA., Stellfeld T; Nuvisan ICB GmbH, 13353 Berlin, Germany., Meyer H; Nuvisan ICB GmbH, 13353 Berlin, Germany., Pütter V; Nuvisan ICB GmbH, 13353 Berlin, Germany., Holton SJ; Nuvisan ICB GmbH, 13353 Berlin, Germany., Korr D; Nuvisan ICB GmbH, 13353 Berlin, Germany., Jerchel-Furau I; Bayer US LLC, Research and Development Precision Molecular Oncology, Cambridge, MA 02142, USA., Pantelidou C; Bayer US LLC, Research and Development Precision Molecular Oncology, Cambridge, MA 02142, USA., Strathdee CA; Cancer Program, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Meyerson M; Cancer Program, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Center for Cancer Genomics, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Department of Genetics and Medicine, Harvard Medical School, Boston, MA 02115, USA., Eis K; Research and Development, Pharmaceuticals, Bayer AG, 13353 Berlin, Germany., Goldstein JT; Cancer Program, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA. Electronic address: jgold@broadinstitute.org.
Publikováno v:
Bioorganic & medicinal chemistry [Bioorg Med Chem] 2023 Jan 15; Vol. 78, pp. 117130. Date of Electronic Publication: 2022 Dec 13.
Autor:
Orsi DL, Pook E, Bräuer N, Friberg A, Lienau P, Lemke CT, Stellfeld T, Brüggemeier U, Pütter V, Meyer H, Baco M, Tang S, Cherniack AD, Westlake L, Bender SA, Kocak M, Strathdee CA, Meyerson M, Eis K, Goldstein JT
Publikováno v:
Journal of medicinal chemistry [J Med Chem] 2023 Jan 12; Vol. 66 (1), pp. 1082. Date of Electronic Publication: 2022 Dec 21.